1.
Chem Commun (Camb)
; 46(15): 2656-8, 2010 Apr 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20461851
RESUMO
(E)-N-trimethylsilyloxyenamines, easily accessible from aldonitrones, proved to be excellent nucleophiles in TMSOTf-induced diastereoselective aldol reaction, both with ketals and acetals, proceeding via an extended transition state and leading to a new aldol C-C-bond in the aldonitrone products, that can be readily hydrolysed to the corresponding aldehydes.