Detalhe da pesquisa
1.
Mechanistic insights into inter-chain disulfide bond reduction of IgG1 and IgG4 antibodies.
Appl Microbiol Biotechnol
; 106(3): 1057-1066, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35072737
2.
A Traceless Site-Specific Conjugation on Native Antibodies Enables Efficient One-Step Payload Assembly.
Angew Chem Int Ed Engl
; 61(36): e202204132, 2022 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35737596
3.
Understanding the pathway and kinetics of aspartic acid isomerization in peptide mapping methods for monoclonal antibodies.
Anal Bioanal Chem
; 413(8): 2113-2123, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33543314
4.
Online/at-line measurement, analysis and control of product titer and critical product quality attributes (CQAs) during process development.
Biotechnol Bioeng
; 117(12): 3757-3765, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32776503
5.
A CFD model for predicting protein aggregation in low-pH virial inactivation for mAb production.
Biotechnol Bioeng
; 117(11): 3400-3412, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32672835
6.
Technology outlook for real-time quality attribute and process parameter monitoring in biopharmaceutical development-A review.
Biotechnol Bioeng
; 117(10): 3182-3198, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32946122
7.
Control of antibody high and low molecular weight species by depth filtration-based cell culture harvesting.
Biotechnol Bioeng
; 116(10): 2610-2620, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31184373
8.
Purity Determination by Capillary Electrophoresis Sodium Hexadecyl Sulfate (CE-SHS): A Novel Application For Therapeutic Protein Characterization.
Anal Chem
; 90(4): 2542-2547, 2018 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29357216
9.
Impact of bilayer lipid composition on the structure and topology of the transmembrane amyloid precursor C99 protein.
J Am Chem Soc
; 136(11): 4093-6, 2014 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24564538
10.
Competition between homodimerization and cholesterol binding to the C99 domain of the amyloid precursor protein.
Biochemistry
; 52(30): 5051-64, 2013 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23865807
11.
The quiet renaissance of protein nuclear magnetic resonance.
Biochemistry
; 52(8): 1303-20, 2013 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23368985
12.
A hydrogen-deuterium exchange mass spectrometry-based protocol for protein-small molecule interaction analysis.
Biophys Rep
; 9(2): 99-111, 2023 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37753061
13.
Conjugation site characterization of antibody-drug conjugates using electron-transfer/higher-energy collision dissociation (EThcD).
Anal Chim Acta
; 1251: 340978, 2023 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36925279
14.
Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology.
Sci Transl Med
; 15(706): eadg3358, 2023 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37494474
15.
Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer.
J Med Chem
; 65(16): 11034-11057, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35925880
16.
Crystal structure of the nonerythroid alpha-spectrin tetramerization site reveals differences between erythroid and nonerythroid spectrin tetramer formation.
J Biol Chem
; 285(19): 14572-84, 2010 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20228407
17.
OsCD1 encodes a putative member of the cellulose synthase-like D sub-family and is essential for rice plant architecture and growth.
Plant Biotechnol J
; 9(4): 513-24, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20955181
18.
Systematic Development of a Size Exclusion Chromatography Method for a Monoclonal Antibody with High Surface Aggregation Propensity (SAP) Index.
J Pharm Sci
; 110(7): 2651-2660, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33812889
19.
Using continuous chromatography methodology to achieve high-productivity and high-purity enrichment of charge variants for analytical characterization.
J Chromatogr A
; 1643: 462008, 2021 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33780880
20.
Important residue (G46) in erythroid spectrin tetramer formation.
Cell Mol Biol Lett
; 15(1): 46-54, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-19756397