Detalhe da pesquisa
1.
A rapid and scalable system for studying gene function in mice using conditional RNA interference.
Cell
; 145(1): 145-58, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21458673
2.
Patient-derived xenografts and in vitro model show rationale for imatinib mesylate repurposing in HEY1-NCoA2-driven mesenchymal chondrosarcoma.
Lab Invest
; 102(9): 1038-1049, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34837064
3.
p53Ψ is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state.
Proc Natl Acad Sci U S A
; 111(32): E3287-96, 2014 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25074920
4.
Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.
Nat Genet
; 37(12): 1315-6, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16258541
5.
Dialogue between RhoA/ROCK and members of the Par complex in cell polarity.
Dev Cell
; 14(2): 150-2, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18267081
6.
TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer.
Proc Natl Acad Sci U S A
; 107(35): 15535-40, 2010 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-20713723
7.
A New Toolkit for Evaluating Gene Functions using Conditional Cas9 Stabilization.
J Vis Exp
; (175)2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34542533
8.
An epigenetic switch regulates the ontogeny of AXL-positive/EGFR-TKi-resistant cells by modulating miR-335 expression.
Elife
; 102021 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34254585
9.
Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.
Proc Natl Acad Sci U S A
; 104(50): 19936-41, 2007 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-18077425
10.
Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development.
Dev Cell
; 2(5): 553-65, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12015964
11.
Increased prevalence of EGFR-mutant lung cancer in women and in East Asian populations: analysis of estrogen-related polymorphisms.
Clin Cancer Res
; 14(13): 4079-84, 2008 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18593984
12.
Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib.
Cancer Res
; 67(5): 2325-30, 2007 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17332364
13.
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib.
N Engl J Med
; 350(21): 2129-39, 2004 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-15118073
14.
SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway.
Mol Cell Biol
; 24(12): 5340-52, 2004 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15169898
15.
Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization.
Nat Commun
; 8: 14370, 2017 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28224990
16.
TGF-ß reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24- cancer cells.
Elife
; 62017 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28092266
17.
The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein.
J Cell Biol
; 216(3): 641-656, 2017 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193700
18.
Effectors and potential targets selectively upregulated in human KRAS-mutant lung adenocarcinomas.
Sci Rep
; 6: 27891, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27301828
19.
The Evolution of TP53 Mutations: From Loss-of-Function to Separation-of-Function Mutants.
J Cancer Biol Res
; 4(4)2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-28191499
20.
TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions.
Elife
; 52016 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27759562