Detalhe da pesquisa
1.
Addressing Ancestry and Sex Bias in Pharmacogenomics.
Annu Rev Pharmacol Toxicol
; 64: 53-64, 2024 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37450899
2.
Causal effect of severe and non-severe malaria on dyslipidemia in African Ancestry individuals: A Mendelian randomization study.
Ann Hum Genet
; 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38488696
3.
Correction: Udosen et al. Meta-Analysis and Multivariate GWAS Analyses in 80,950 Individuals of African Ancestry Identify Novel Variants Associated with Blood Pressure Traits. Int. J. Mol. Sci. 2023, 24, 2164.
Int J Mol Sci
; 25(7)2024 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38612946
4.
Meta-analysis of African ancestry genome-wide association studies identified novel locus and validates multiple loci associated with kidney function.
BMC Genomics
; 24(1): 496, 2023 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37644460
5.
Benzimidazole compound abrogates SARS-COV-2 receptor-binding domain (RBD)/ACE2 interaction In vitro.
Microb Pathog
; 176: 105994, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36682669
6.
Meta-Analysis and Multivariate GWAS Analyses in 77,850 Individuals of African Ancestry Identify Novel Variants Associated with Blood Pressure Traits.
Int J Mol Sci
; 24(3)2023 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36768488
7.
Genetic loci implicated in meta-analysis of body shape in Africans.
Nutr Metab Cardiovasc Dis
; 32(6): 1511-1518, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35461751
8.
Metabolic Traits and Stroke Risk in Individuals of African Ancestry: Mendelian Randomization Analysis.
Stroke
; 52(8): 2680-2684, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34078102
9.
Insight into the Therapeutic Potential of a Bicyclic Hydroxypyridone Compound 2-[(2,4-Dichlorophenyl)methyl]-7-hydroxy-1,2,3,4-tetrahydro-8H-pyrido[1,2-a]pyrazin-8-one as COMT Inhibitor in the Treatment of Parkinson's Disease: A Molecular Dynamic Simulation Approach.
Chem Biodivers
; 18(9): e2100204, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34252268
10.
Investigating the Mechanistic Inhibitory Discrepancies of Novel Halogen and Alkyl Di-Substituted Oxadiazole-Based Dibenzo-Azepine-Dione Derivatives on Poly (ADP-Ribose) Polymerase-1.
Chem Biodivers
; 18(1): e2000802, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33289285
11.
Development of Halogenated Pyrazolines as Selective Monoamine Oxidase-B Inhibitors: Deciphering via Molecular Dynamics Approach.
Molecules
; 26(11)2021 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34071665
12.
Genetically Proxied Lipid-Lowering Drug Target Perturbation and Ischemic Stroke Risk in European and African Ancestry Individuals: Mendelian Randomization Study.
Stroke
; 2024 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38860386
13.
An in-silico analysis of OGT gene association with diabetes mellitus.
BMC Res Notes
; 17(1): 89, 2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38539217
14.
An In Silico Functional Analysis of Non-Synonymous Single-Nucleotide Polymorphisms of Bovine CMAH Gene and Potential Implication in Pathogenesis.
Pathogens
; 12(4)2023 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37111477
15.
Genetic heterogeneity in cardiovascular disease across ancestries: Insights for mechanisms and therapeutic intervention.
Camb Prism Precis Med
; 1: e8, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38550935
16.
Leveraging information between multiple population groups and traits improves fine-mapping resolution.
Nat Commun
; 14(1): 7279, 2023 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37949886
17.
Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations.
PLoS One
; 18(2): e0280344, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36809439
18.
Identification of promising high-affinity inhibitors of SARS-CoV-2 main protease from African Natural Products Databases by Virtual Screening.
Res Sq
; 2023 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36993208
19.
Therapeutic Path to Triple Knockout: Investigating the Pan-inhibitory Mechanisms of AKT, CDK9, and TNKS2 by a novel 2-Phenylquinazolinone derivative in Cancer Therapy- An In-Silico Investigation.
Curr Pharm Biotechnol
; 2023 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37581526
20.
Multi-dimensional structural footprint identification for the design of potential scaffolds targeting METTL3 in cancer treatment from natural compounds.
J Mol Model
; 29(4): 122, 2023 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36995499