Initiation of a ring approach to infection prevention and control at non-Ebola health care facilities - Liberia, January-February 2015.

From mid-January to mid-February 2015, all confirmed Ebola virus disease (Ebola) cases that occurred in Liberia were epidemiologically linked to a single index patient from the St. Paul Bridge area of Montserrado County. Of the 22 confirmed patients in this cluster, eight (36%) sought and received care from at least one of 10 non-Ebola health care facilities (HCFs), including clinics and hospitals in Montserrado and Margibi counties, before admission to an Ebola treatment unit. After recognition that three patients in this emerging cluster had received care from a non-Ebola treatment unit, and in response to the risk for Ebola transmission in non-Ebola treatment unit health care settings, a focused infection prevention and control (IPC) rapid response effort for the immediate area was developed to target facilities at increased risk for exposure to a person with Ebola (Ring IPC). The Ring IPC approach, which provided rapid, intensive, and short-term IPC support to HCFs in areas of active Ebola transmission, was an addition to Liberia's proposed longer term national IPC strategy, which focused on providing a comprehensive package of IPC training and support to all HCFs in the country. This report describes possible health care worker exposures to the cluster's eight patients who sought care from an HCF and implementation of the Ring IPC approach. On May 9, 2015, the World Health Organization (WHO) declared the end of the Ebola outbreak in Liberia.

Éclampsie en réanimation polyvalente: facteurs déterminants du décès / Eclampsia in polyvalent intensive care unit: determinants of death

Contexte et objectif . L'éclampsie étant une cause majeure de mortalité maternelle, notre objectif était de décrire l'évolution et identifi er les facteurs prono stics des éclampsies admises en réanimation. Méthodes. Etude rétrospective, analytique portant sur les cas d'éclampsie admis du 01 janvier 2015 au 31 décembre 2019. Les données étudiées étaient d'ordres épidémio-clinique, thérapeutique et évolutif. L'analyse a été réalisée à l'aide du test de Fisher au seuil de signifi cativité 5%. Résultats. Soixante-douze (72) dossiers ont été retenus et la prévalence était de 5,46%. L'âge moyen était de 23,87 ans ± 1,52. Les crises étaient survenues en anté partum à 52,78%. Une césarienne a été réalisée dans 65,28% des cas. Les anticonvulsivants les plus utilisés étaient le phénobarbital (51,39%), le sulfate de magnésium (38,89%) et le diazépam (26,39%). La ventilation mécanique a été indiquée dans certains cas : 38,89%. Nous avons observé des complications dans 59,72% des cas dont les plus fréquentes étaient le syndrome d'hémolyse, de cytolyse hépatique et de thrombopénie (30,56%), l'état de mal convulsif (25%) et l'insuffi sance rénale aigüe (19,44%). La mortalité était de 12,5%. Les facteurs de mauvais pronostic étaient la ventilation mécanique et la présence de certaines complications. Les facteurs améliorant le pronostic étaient l'éclampsie du post partum et le sulfate de magnésium. Conclusion. Les complications étaient fréquentes, la mortalité élevée et les facteurs pronostics concernaient la période de survenue des convulsions, le type de complications associées et les moyens de prise en charge

Context and objective. Eclampsia being a major cause of maternal mortality, our objective was to describe the evolution and identify the prognostic factors of eclampsia admitted to intensive care. Methods. R0etrospective, analytical study of cases of eclampsia admitted from January 1, 2015 to December 31, 2019. The data studied were epidemiologicalclinical, therapeutic and evolutionary. The analysis was carried out using Fisher's test at the 5% signifi cance level. Results. 72 fi les were retained and the prevalence was 5.46%. The mean age was 23.87 years ± 1.52. The seizures had occurred antepartum in 52.78%. A caesarean section was performed in 65.28% of cases. The most used anticonvulsants were phenobarbital (51.39%), magnesium sulphate (38.89%) and diazepam (26.39%). Mechanical ventilation was indicated in some cases: 38.89%. We observed complications in 59.72% of cases, the most frequent of which were hemolysis syndrome, hepatic cytolysis and thrombocytopenia (30.56%), convulsive status epilepticus (25%) and insufficiency acute renal (19.44%). Mortality was 12.5%. The poor prognostic factors were mechanical ventilation and the presence of certain complications. The factors improving the prognosis were postpartum eclampsia and magnesium sulphate. Conclusion. Complications were frequent, mortality high and the prognostic factors concerned the period of onset of the seizures, the type of associated complications and the means of management.