Detalhe da pesquisa
1.
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease.
Biochem J
; 478(13): 2499-2515, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34198327
2.
Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity.
J Am Chem Soc
; 142(28): 12020-12026, 2020 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32579346
3.
Discovery of a novel fluorescent chemical probe suitable for evaluation of neuropilin-1 binding of small molecules.
Drug Dev Res
; 81(4): 491-500, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31958155
4.
Correction to "Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity".
J Am Chem Soc
; 142(35): 15199, 2020 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32812749
5.
Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes.
Biochem J
; 451(2): 329-42, 2013 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23418854
6.
A palmitoyl transferase chemical-genetic system to map ZDHHC-specific S-acylation.
Nat Biotechnol
; 2024 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38191663
7.
Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFß) Production in Regulatory T-Cells.
J Med Chem
; 61(9): 4135-4154, 2018 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29648813
8.
3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: highly potent and selective inhibitors of the type 5 17-ß-hydroxysteroid dehydrogenase AKR1C3.
J Med Chem
; 55(17): 7746-58, 2012 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22877157
9.
Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling.
PLoS One
; 7(1): e28568, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22253692