Detalhe da pesquisa
1.
Recovery of motor function is associated with rescue of glutamate biomarkers in the striatum and motor cortex following treatment with Mucuna pruriens in a murine model of Parkinsons disease.
Mol Cell Neurosci
; 126: 103883, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37527694
2.
Integrating High-Resolution Mass Spectral Data, Bioassays and Computational Models to Annotate Bioactives in Botanical Extracts: Case Study Analysis of C. asiatica Extract Associates Dicaffeoylquinic Acids with Protection against Amyloid-ß Toxicity.
Molecules
; 29(4)2024 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38398590
3.
Caffeoylquinic acids: chemistry, biosynthesis, occurrence, analytical challenges, and bioactivity.
Plant J
; 107(5): 1299-1319, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34171156
4.
Centella asiatica Water Extract Shows Low Potential for Cytochrome P450-Mediated Drug Interactions.
Drug Metab Dispos
; 48(10): 1053-1063, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32581050
5.
Integration of mass spectral fingerprinting analysis with precursor ion (MS1) quantification for the characterisation of botanical extracts: application to extracts of Centella asiatica (L.) Urban.
Phytochem Anal
; 31(6): 722-738, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32281154
6.
Centella asiatica attenuates hippocampal mitochondrial dysfunction and improves memory and executive function in ß-amyloid overexpressing mice.
Mol Cell Neurosci
; 93: 1-9, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30253196
7.
Centella asiatica - Phytochemistry and mechanisms of neuroprotection and cognitive enhancement.
Phytochem Rev
; 17(1): 161-194, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31736679
8.
Amelioration of age-related cognitive decline and anxiety in mice by Centella asiatica extract varies by sex, dose and mode of administration.
bioRxiv
; 2024 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38328129
9.
Mode of administration influences plasma levels of active Centella asiatica compounds in 5xFAD mice while markers of neuroinflammation remain unaltered.
Front Neurosci
; 18: 1277626, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38591068
10.
Amelioration of age-related cognitive decline and anxiety in mice by Centella asiatica extract varies by sex, dose and mode of administration.
Front Aging
; 5: 1357922, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38770167
11.
Chlorogenic Acids, Acting via Calcineurin, Are the Main Compounds in Centella asiatica Extracts That Mediate Resilience to Chronic Stress in Drosophila melanogaster.
Nutrients
; 15(18)2023 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37764799
12.
Quantification of Caffeoylquinic Acids and Triterpenes as Targeted Bioactive Compounds of Centella asiatica in Extracts and Formulations by Liquid Chromatography Mass Spectrometry.
J Chromatogr Open
; 42023 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37789901
13.
Bioanalytical method validation and application to a phase 1, double-blind, randomized pharmacokinetic trial of a standardized Centella asiatica (L.) Urban water extract product in healthy older adults.
Front Pharmacol
; 14: 1228030, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37680716
14.
Perspective: Council for Responsible Nutrition Science in Session. Optimizing Health with Nutrition-Opportunities, Gaps, and the Future.
Adv Nutr
; 14(5): 948-958, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37270030
15.
Centella asiatica promotes antioxidant gene expression and mitochondrial oxidative respiration in experimental autoimmune encephalomyelitis.
Res Sq
; 2023 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37886497
16.
Withania somnifera Extracts Promote Resilience against Age-Related and Stress-Induced Behavioral Phenotypes in Drosophila melanogaster; a Possible Role of Other Compounds besides Withanolides.
Nutrients
; 14(19)2022 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36235577
17.
Withania somnifera and Centella asiatica Extracts Ameliorate Behavioral Deficits in an In Vivo Drosophila melanogaster Model of Oxidative Stress.
Antioxidants (Basel)
; 11(1)2022 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35052625
18.
The Impact of the hAPP695SW Transgene and Associated Amyloid-ß Accumulation on Murine Hippocampal Biochemical Pathways.
J Alzheimers Dis
; 85(4): 1601-1619, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34958022
19.
Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Centella asiatica Product in Cognitively Impaired Older Adults: A Phase 1, Double-Blind, Randomized Clinical Trial.
Antioxidants (Basel)
; 11(2)2022 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35204098
20.
Effects of Withania somnifera (Ashwagandha) on Stress and the Stress- Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia.
Curr Neuropharmacol
; 19(9): 1468-1495, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34254920