Detalhe da pesquisa
1.
Dynamics of broad H3K4me3 domains uncover an epigenetic switch between cell identity and cancer-related genes.
Genome Res
; 32(7): 1328-1342, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34162697
2.
Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers.
Genome Res
; 32(7): 1343-1354, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34933939
3.
IL-7 receptor expression is frequent in T-cell acute lymphoblastic leukemia and predicts sensitivity to JAK inhibition.
Blood
; 142(2): 158-171, 2023 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37023368
4.
Epromoters are new players in the regulatory landscape with potential pleiotropic roles.
Bioessays
; 45(10): e2300012, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37246247
5.
Short tandem repeats are important contributors to silencer elements in T cells.
Nucleic Acids Res
; 51(10): 4845-4866, 2023 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36929452
6.
PRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL.
Blood
; 138(19): 1855-1869, 2021 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34125178
7.
TAL1 activation in T-cell acute lymphoblastic leukemia: a novel oncogenic 3' neo-enhancer.
Haematologica
; 108(5): 1259-1271, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36632736
8.
Widespread Enhancer Activity from Core Promoters.
Trends Biochem Sci
; 43(6): 452-468, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29673772
9.
Identification of ATP2B4 Regulatory Element Containing Functional Genetic Variants Associated with Severe Malaria.
Int J Mol Sci
; 23(9)2022 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35563239
10.
Low level CpG island promoter methylation predicts a poor outcome in adult T-cell acute lymphoblastic leukemia.
Haematologica
; 105(6): 1575-1581, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31537687
11.
Understanding enhancer function to understand human disease.
Bioessays
; 45(10): e2300149, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37641890
12.
Protein complexes associated with ß-catenin differentially influence the differentiation profile of neonatal and adult CD8+ T cells.
J Cell Physiol
; 234(10): 18639-18652, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30924167
13.
Dynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation.
Nucleic Acids Res
; 44(8): 3567-85, 2016 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26673693
14.
Transcription-dependent generation of a specialized chromatin structure at the TCRß locus.
J Immunol
; 194(7): 3432-43, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25732733
15.
Integrative analysis of public ChIP-seq experiments reveals a complex multi-cell regulatory landscape.
Nucleic Acids Res
; 43(4): e27, 2015 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25477382
16.
An early thymic precursor phenotype predicts outcome exclusively in HOXA-overexpressing adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study.
Haematologica
; 101(6): 732-40, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26944475
17.
H3K4 tri-methylation provides an epigenetic signature of active enhancers.
EMBO J
; 30(20): 4198-210, 2011 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21847099
18.
CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters.
Genome Res
; 22(12): 2399-408, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23100115
19.
Active STAT5 regulates T-bet and eomesodermin expression in CD8 T cells and imprints a T-bet-dependent Tc1 program with repressed IL-6/TGF-ß1 signaling.
J Immunol
; 191(7): 3712-24, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24006458
20.
Extensive molecular mapping of TCRα/δ- and TCRß-involved chromosomal translocations reveals distinct mechanisms of oncogene activation in T-ALL.
Blood
; 120(16): 3298-309, 2012 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22948044