Detalhe da pesquisa
1.
Renin and renin blockade have no role in complement activity.
Kidney Int
; 105(2): 328-337, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38008161
2.
Allosteric Tuning of Caspase-7: Establishing the Nexus of Structure and Catalytic Power.
Chemistry
; 29(40): e202301621, 2023 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37285583
3.
A stereochemical journey around spirocyclic glutamic acid analogs.
Org Biomol Chem
; 20(15): 3183-3200, 2022 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35348173
4.
Allosteric Tuning of Caspase-7: A Fragment-Based Drug Discovery Approach.
Angew Chem Int Ed Engl
; 56(46): 14443-14447, 2017 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28940929
5.
Inhibition of Pseudomonas aeruginosa ExsA DNA-Binding Activity by N-Hydroxybenzimidazoles.
Antimicrob Agents Chemother
; 60(2): 766-76, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26574012
6.
Contributions of the RAD51 N-terminal domain to BRCA2-RAD51 interaction.
Nucleic Acids Res
; 41(19): 9020-32, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23935068
7.
Flooding enzymes: quantifying the contributions of interstitial water and cavity shape to ligand binding using extended linear response free energy calculations.
J Chem Inf Model
; 53(9): 2349-59, 2013 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24111836
8.
Therapeutic disruption of RAD52-ssDNA complexation via novel drug-like inhibitors.
NAR Cancer
; 5(2): zcad018, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37139244
9.
Human RAD52 double-ring remodels replication forks restricting fork reversal.
bioRxiv
; 2023 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38014173
10.
A moving target for drug discovery: Structure activity relationship and many genome (de)stabilizing functions of the RAD52 protein.
DNA Repair (Amst)
; 120: 103421, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36327799
11.
Decrypting a Cryptic Allosteric Pocket in H. pylori Glutamate Racemase.
Commun Chem
; 42021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35673630
12.
Decrypting a cryptic allosteric pocket in H. pylori glutamate racemase.
Commun Chem
; 4(1): 172, 2021 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36697800
13.
An Atomistic Understanding of Allosteric Inhibition of Glutamate Racemase: a Dampening of Native Activation Dynamics.
ChemMedChem
; 15(4): 376-384, 2020 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31876113
14.
Biochemical analysis of a beta-D-xylosidase and a bifunctional xylanase-ferulic acid esterase from a xylanolytic gene cluster in Prevotella ruminicola 23.
J Bacteriol
; 191(10): 3328-38, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19304844
15.
Determinants of catalytic power and ligand binding in glutamate racemase.
J Am Chem Soc
; 131(14): 5274-84, 2009 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19309142
16.
Integrating Experimental and In Silico HTS in the Discovery of Inhibitors of Protein-Nucleic Acid Interactions.
Methods Enzymol
; 601: 243-273, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29523234
17.
Elucidating the Catalytic Power of Glutamate Racemase by Investigating a Series of Covalent Inhibitors.
ChemMedChem
; 13(23): 2514-2521, 2018 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30264520
18.
Small-Molecule Inhibitors Targeting DNA Repair and DNA Repair Deficiency in Research and Cancer Therapy.
Cell Chem Biol
; 24(9): 1101-1119, 2017 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28938088
19.
Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells.
Elife
; 52016 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27434671
20.
Biosynthesis of a Novel Glutamate Racemase Containing a Site-Specific 7-Hydroxycoumarin Amino Acid: Enzyme-Ligand Promiscuity Revealed at the Atomistic Level.
ACS Cent Sci
; 1(7): 364-373, 2015 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26539562