Detalhe da pesquisa
1.
MICU3 Regulates Mitochondrial Calcium and Cardiac Hypertrophy.
Circ Res
; 135(1): 26-40, 2024 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38747181
2.
Loss of mitochondrial Ca2+ uptake protein 3 impairs skeletal muscle calcium handling and exercise capacity.
J Physiol
; 602(1): 113-128, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38018177
3.
SARS-CoV-2 ORF3a expression in brain disrupts the autophagy-lysosomal pathway, impairs sphingolipid homeostasis, and drives neuropathogenesis.
FASEB J
; 37(5): e22919, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37071464
4.
IFN-γ and androgens disrupt mitochondrial function in murine myocytes.
J Pathol
; 260(3): 276-288, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37185821
5.
Glb1 knockout mouse model shares natural history with type II GM1 gangliosidosis patients.
Mol Genet Metab
; 138(2): 107508, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36709532
6.
Therapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases.
Blood
; 137(18): 2509-2519, 2021 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33512384
7.
Baz1b Dosage Influences Cardiovascular Function, Predisposing to Dilated Cardiomyopathy.
FASEB J
; 36 Suppl 12022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35723872
8.
Neuron-specific ablation of eIF5A or deoxyhypusine synthase leads to impairments in growth, viability, neurodevelopment, and cognitive functions in mice.
J Biol Chem
; 297(5): 101333, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34688659
9.
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations.
Hum Mol Genet
; 29(9): 1547-1567, 2020 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32338760
10.
p53 prevents doxorubicin cardiotoxicity independently of its prototypical tumor suppressor activities.
Proc Natl Acad Sci U S A
; 116(39): 19626-19634, 2019 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31488712
11.
Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice.
PLoS Genet
; 15(10): e1008424, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31622341
12.
X-linked creatine transporter deficiency results in prolonged QTc and increased sudden death risk in humans and disease model.
Genet Med
; 23(10): 1864-1872, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34050321
13.
Conditional ablation and conditional rescue models for Casq2 elucidate the role of development and of cell-type specific expression of Casq2 in the CPVT2 phenotype.
Hum Mol Genet
; 27(9): 1533-1544, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29452352
14.
Systemic Succinate Homeostasis and Local Succinate Signaling Affect Blood Pressure and Modify Risks for Calcium Oxalate Lithogenesis.
J Am Soc Nephrol
; 30(3): 381-392, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30728179
15.
Compound D159687, a phosphodiesterase 4D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive function.
Biochem Biophys Res Commun
; 506(4): 1059-1064, 2018 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30409425
16.
Mice expressing reduced levels of hepatic glucose-6-phosphatase-α activity do not develop age-related insulin resistance or obesity.
Hum Mol Genet
; 24(18): 5115-25, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26089201
17.
MICU3 Plays an Important Role in Cardiovascular Function.
Circ Res
; 127(12): 1571-1573, 2020 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33059536
18.
SMAD3 negatively regulates serum irisin and skeletal muscle FNDC5 and peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) during exercise.
J Biol Chem
; 290(12): 7671-84, 2015 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25648888
19.
Assessment of cardiac function in mice lacking the mitochondrial calcium uniporter.
J Mol Cell Cardiol
; 85: 178-82, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26057074
20.
Neuronal nitric oxide synthase required for erythropoietin modulation of heart function in mice.
Front Physiol
; 15: 1338476, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38628440