Prevalence of urinary incontinence in women with osteoporosis.

OBJECTIVE: To investigate the prevalence and frequency of urinary incontinence in women presenting to a specialist osteoporosis clinic. METHODS: Participants included 412 female patients aged 22 to 94 years (mean 62 years) presenting to a hospital-based specialist multidisciplinary osteoporosis clinic over one year. The presence or absence of urinary incontinence, urgency without leakage, type of symptoms (stress, urge, mixed) and frequency of urinary incontinence were recorded. RESULTS: Sixty-seven percent of patients (277/412) reported some symptoms of urinary incontinence, 23% reported no symptoms and 10% reported urgency without any leakage. Of those who reported some urinary incontinence, 51% reported symptoms of stress incontinence, urgency, and urge incontinence. Almost 40% of all patients (163/412) and 59% of those with any urinary incontinence (163/277) reported leakage at least once per week. CONCLUSION: The prevalence of at least weekly urinary incontinence in this population is much higher than that reported in studies of other older adult female populations. There is also a high prevalence of incontinence accompanied by urgency in women with osteoporosis. Based on these results and because urinary incontinence can limit a woman's ability to be physically active and increase the risk of falls and fractures, screening for incontinence should be a routine part of osteoporosis management. Clinicians seeing patients for osteoporosis should consider the presence of incontinence when prescribing exercise for bone health and fall prevention.

Regional trabecular morphology assessed by micro-CT is correlated with failure of aged thoracic vertebrae under a posteroanterior load and may determine the site of fracture.

INTRODUCTION: Spinal mobilization is commonly used in the treatment of patients with back pain, including individuals with osteoporosis. Previous data indicated that traditional predictors of skeletal failure-lateral or anteroposterior bone mineral density (BMD) by dual energy X-ray absorptiometry (DXA) or geometry of the spinous process or vertebral body-do not predict failure load during posteroanterior spinal mobilization. Morphological differences and inhomogeneities in BMD may have important effects on vertebral strength but integral BMD values by DXA cannot reflect these potentially important differences. We investigated the determinants of spinal fracture using muCT. MATERIALS AND METHODS: We measured failure load and failure site in 11 T5-8 cadaveric specimens (mean age 78 years) when a posteroanterior load was applied at the spinous process of T6 using a servohydraulic material testing machine. Radiography and CT scan were used to verify failure site. We observed no damage to the adjacent T7 vertebrae following the T6 posteroanterior failure test. The T7 vertebrae were sectioned to produce regional samples of the spinous process, the lamina and a vertebral body core. Each sample was scanned with muCT to measure bone microarchitectural parameters. We segmented and analysed four trabecular regions (spinous process base and middle, central lamina and central vertebral body). We used one-way repeated measures ANOVA to compare regions and computed Pearson correlations to assess the relation between PA failure load of T6 and the morphological parameters of T7. RESULTS: The BV/TV at the base or middle of the T7 spinous process (fracture sites), Tb.N and Tb.Th at the base were significantly correlated with posteroanterior failure load of T6 (BV/TV base: r=0.74, p=0.01; BV/TV middle: r=0.73, p=0.01; Tb.N base: r=0.64, p=0.03; Tb.Th base: r=0.65, p=0.03). The Tb.Th of the lamina was significantly greater than Tb.Th of the spinous process base (p=0.002). CONCLUSIONS: Whereas previous data indicated that BMD by DXA was not a good predictor of posteroanterior failure load, regional BV/TV of the spinous process base and middle regions, the sites of fracture, are correlated with posteroanterior failure load. Trabecular thickness differed significantly between the base of the spinous process and the lamina, and may have influenced the site of fracture.

Physical therapy for urinary incontinence in postmenopausal women with osteoporosis or low bone density: a randomized controlled trial.

OBJECTIVE: To assess the effectiveness of 12 weekly physical therapy sessions for urinary incontinence (UI) compared with a control intervention, for reducing the number of UI episodes measured with the 7-day bladder diary, at 3 months and 1 year postrandomization. METHODS: A single parallel-group randomized controlled trial was conducted at one outpatient public health center, in postmenopausal women aged 55 years and over with osteoporosis or low bone density and UI. Women were randomized to physical therapy (PT) for UI or osteoporosis education. The primary outcome measure was number of leakage episodes on the 7-day bladder diary, assessed at baseline, after treatment and at 1 year. The secondary outcome measures included the pad test and disease-specific quality of life and self-efficacy questionnaires assessed at the same timepoints. RESULTS: Forty-eight women participated (24 per group). Two participants dropped out of each group and one participant was deceased before 3-month follow-up. Intention-to-treat analysis was undertaken. At 3 months and 1 year, there was a statistically significant difference in the number of leakage episodes on the 7-day bladder diary (3 mo: P = 0.04; 1 y: P = 0.01) in favor of the PT group. The effect size was 0.34 at 1 year. There were no harms reported. CONCLUSIONS: After a 12-week course of PT once per week for UI, PT group participants had a 75% reduction in weekly median number of leakage episodes, whereas the control group's condition had no improvement. At 1 year, the PT group participants maintained this improvement, whereas the control group's incontinence worsened.

Physiotherapy and osteoporosis: practice behaviors and clinicians' perceptions--a survey.

Physiotherapists typically use a variety of modes to treat their clients, including manual therapy. The literature cautions against the use of manual therapy in individuals with osteoporosis, (Musculoskeletal Manipulation: Evaluation of the Scientific Evidence, Charles C Thomas Publisher, Springfield, IL; Common Vertebral Joint Problems, 2nd Edition, Churchill Livingstone, New York; Maitland's Vertebral Manipulation, 6th Edition, Butterworth-Heinemann, Boston; Br. J. Sports Med. 37 (2003) 195-196) yet clinical experience (Br. J. Sports Med. 37 (2003) 195-196) and published cases (J. Manip. Physiol. Ther. 15(7) (1992) 450-454) suggest that these techniques are still being used by at least some clinicians. The purpose of this study was to measure the most common treatment modes used by a random sample of physiotherapists practicing in the province of British Columbia (BC) in the treatment of individuals with osteoporosis. To assess whether physiotherapists in BC have concerns about the use of manual therapy in individuals with osteoporosis, particularly whether physiotherapists have concerns about fracture as a complication of treatment. This cross-sectional study of 171 physiotherapists in BC used a questionnaire developed by the physiotherapist in the Osteoporosis Program at the BC Women's Health Centre (a part of the Children's & Women's Health Centre of BC). The response rate (67/171) was 39%. Ninety-seven per cent of respondents reported using strength exercises and postural reeducation, while 45% reported using manual therapy in this population. Ninety-one per cent of respondents reported having concerns about the use of manual therapy. Vertebral fracture and rib fracture were the most commonly reported concerns. These findings suggest that most physiotherapists practicing in BC, Canada use evidence-based methods (i.e. strength training) when treating individuals with osteoporosis, a large number use manual therapy, and most have concerns about its use. Physiotherapists are most concerned about fractures, in particular vertebral fracture, but injury to other musculoskeletal tissues is also of concern. Studies of safety and effectiveness of manual therapy in this population are needed to guide clinical practice.

Posteroanterior stiffness predicts sagittal plane midthoracic range of motion and three-dimensional flexibility in cadaveric spine segments.

BACKGROUND: Spinal joint mobilization is a mainstay of clinical assessment of individuals with back pain. The clinician manually assesses stiffness and joint motion relative to segments above and below. Although clinical theory suggests that manually performed techniques can predict or detect intervertebral motion, this hypothesis remains untested. METHODS: Using a precision opto-electronic camera system and a custom spine testing machine, we measured intervertebral range of motion, neutral zone motion and three-dimensional flexibility in eight T5-T8 cadaveric specimens (mean age=81 years). We then measured stiffness when a cyclic posteroanterior load was applied at the spinous process of T6 using a servohydraulic material testing machine (Instron 8874), simulating the posteroanterior spinal mobilization technique. FINDINGs. There was a strong significant inverse relationship between stiffness during cyclic posteroanterior loading of T6 and flexion or extension range of motion of T6 relative to T7 (r=-0.88, P<0.01, extension; r=-0.81, P=0.01, flexion), and T6-T7 flexibility in all six directions. INTERPRETATION: Stiffness during simulated central cyclic posteroanterior mobilization in the cadaveric midthoracic spine is inversely correlated with flexion and extension range of motion and three-dimensional flexibility at the level at which the technique is applied. These findings provide biomechanical support for the inclusion of specific joint mobilization in the assessment of older adults with back pain.

Transmission of force in the lumbosacral spine during backward falls.

STUDY DESIGN: Mathematical model, combined with and verified using human subject data. OBJECTIVE: (1) To develop and verify a lumped-parameter mathematical model for prediction of spine forces during backward falls; (2) to use this model to evaluate the effect of floor stiffness on spine forces during falls; and (3) to compare predicted impact forces with forces previously measured to fracture the spine. SUMMARY OF BACKGROUND DATA: Vertebral fractures are the most common osteoporotic fractures and commonly result from falls from standing height. Compliant flooring reduces the force at the ground during a backward fall from standing; however, the effect on spine forces is unknown. METHODS: A 6-df model of the body was developed and verified using data from 10 human subjects falling from standing onto 3 types of compliant floors (soft: 59 kN/m, medium: 67 kN/m, and firm: 95 kN/m). The simulated ground forces were compared with those measured experimentally. The model was also used to assess the effect of floor stiffness on spine forces at various intervertebral levels. RESULTS: There was less than 14% difference between model predictions and experimentally measured peak ground reaction forces, when averaged over all floor conditions. When compared with the rigid floor, average peak spine force attenuations of 46%, 43%, and 41% were achieved with the soft, medium, and firm floors, respectively (3.7, 3.9, 4.1 kN vs. 6.9 kN at L4/L5). Spine forces were lower than those at the ground and decreased cranially (4.9, 3.9, 3.7, 3.5 kN at the ground, L5/S1, L4/L5, and L3/L4, respectively, for the soft floor). CONCLUSION: Lowering the floor stiffness (from 400 to 59 kN/m) can attenuate peak lumbosacral spine forces in a backward fall onto the buttocks from standing by 46% (average peak from 6.9 to 3.7 kN at L4/L5) to values closer to the average tolerance of the spine to fracture (3.4 kN).

Age differences in energy absorption in the upper extremity during a descent movement: implications for arresting a fall.

BACKGROUND: Falls are the number one cause of unintentional injury in older adults. The protective response of "breaking the fall" with the outstretched hand is often essential for avoiding injury to the hip and head. In this study, we compared the ability of young and older women to absorb the impact energy of a fall in the outstretched arms. METHODS: Twenty young (mean age = 21 years) and 20 older (M = 78 years) women were instructed to slowly lower their body weight, similar to the descent phase of a push-up, from body lean angles ranging from 15 degrees to 90 degrees . Measures were acquired of peak upper extremity energy absorption, arm deflection, and hand contact force. RESULTS: On average, older women were able to absorb 45% less energy in the dominant arm than young women (1.7 +/- 0.5% vs 3.1 +/- 0.4% of their body weight x body height; p < .001). These results suggest that, even when both arms participate equally, the average energy content of a forward fall exceeds by 5-fold the average energy that our older participants could absorb and exceeds by 2.7-fold the average energy that young participants could absorb. CONCLUSIONS: During a descent movement that simulates fall arrest, the energy-absorbing capacity of the upper extremities in older women is nearly half that of young women. Absorbing the full energy of a fall in the upper extremities is a challenging task even for healthy young women. Strengthening of upper extremity muscles should enhance this ability and presumably reduce the risk for injury to the hip and head during a fall.

Postgraduate physiotherapy training: interest and perceived barriers to participation in a clinical master's degree programme.

PURPOSE: To (1) assess whether physiotherapists in a large Canadian province support the offering of a clinical master's degree programme; (2) identify what sector of this population is interested in participating in a clinical master's degree programme; (3) identify the most common personal/professional reasons for enrolling; (4) identify the type of programme that would appeal; and (5) assess barriers to participation in such a programme. METHODS: The survey and accompanying cover letter explaining the study were sent by postal mail to all 2,552 physiotherapists registered with the College of Physical Therapists of British Columbia (CPTBC). RESULTS: The response rate was 17%; 90% of respondents support offering this type of physiotherapy degree in BC, and 14% reported that they were likely to enrol. Orthopaedics/manual therapy (41%) was the clinical area of most interest. CONCLUSIONS: There is strong support for a clinical master's degree in orthopaedic manual therapy in BC. There is greater support for a part-time programme with an inter-professional component, using a combination of e-learning and classroom teaching to reduce travel time and time away from family.

Preventing fall-related vertebral fractures: effect of floor stiffness on peak impact forces during backward falls.

STUDY DESIGN: In vivo biomechanical study of 11 male volunteers. OBJECTIVE: To measure the peak forces applied to the buttocks in a backward fall from standing, and to determine whether this force is lowered by reductions in floor stiffness. SUMMARY OF BACKGROUND DATA: Fall-related vertebral fractures are common and backward falls result in impact to the buttocks. Compliant flooring may reduce impact force and risk for vertebral fracture during a fall. However, we have little knowledge of the peak forces applied to the body during a backward fall, or how floor stiffness affects this force. METHODS: Eleven males, mean age 25 +/- 5 (SD) years, were suddenly released from a backward lean of 15 degrees , falling backward onto the ground which was covered with 4.5, 7.5, or 10.5 cm of ethylene vinyl acetate foam rubber. We measured 3-dimensional impact forces applied to the buttocks at 960 Hz with a force plate. We used repeated measures analysis of variance and post hoc t tests to compare peak forces between conditions. We also modeled peak vertical force for falls onto a bare floor. RESULTS.: There was a significant difference in peak vertical force between falls onto the 10.5 cm foam condition compared with the 7.5 cm (P = 0.002) and 4.5 cm (P < 0.001) conditions. Peak vertical force (N) was (mean +/- SD) 5099 +/- 868, 4788 +/- 702, and 4544 +/- 672 for the 4.5, 7.5, and 10.5 cm foam conditions, respectively, and estimated at 6027 +/- 988 for the rigid (bare floor) condition. Compared with the bare floor, these foam floors provided, on average, 24, 20, and 15% force attenuation respectively. CONCLUSION: In a backward fall onto the buttocks, peak impact forces are 6.4 to 9.0 times body weight in a fall onto a bare floor. Reducing floor stiffness using even a thin (4.5 cm) layer of foam may provide 15% vertical force attenuation during a fall onto the buttocks.

Exercise for fall risk reduction in community-dwelling older adults: a systematic review.

PURPOSE: To evaluate the influence of exercise on falls and fall risk reduction in community-dwelling older adults and to present an updated synthesis of outcome measures for the assessment of fall risk in community-dwelling older adults. METHOD: A systematic review was performed, considering English-language articles published from 2000 to 2006 and accessible through MEDLINE, CINAHL, PEDro, EMBASE, and/or AMED. Included were randomized controlled clinical trials (RCTs) that used an exercise or physical activity intervention and involved participants over age 50. Screening and methodological quality for internal validity were conducted by two independent reviewers. RESULTS: The search retrieved 156 abstracts; 22 articles met the internal validity criteria. Both individualized and group exercise programmes were found to be effective in reducing falls and fall risk. The optimal type, frequency, and dose of exercise to achieve a positive effect have not been determined. A variety of outcome measures have been used to measure fall risk, especially for balance. CONCLUSIONS: Falls and fall risk can be reduced with exercise interventions in the community-dwelling elderly, although the most effective exercise variables are unknown. Future studies in populations with comorbidities known to increase fall risk will help determine optimal, condition-specific fall-prevention programmes. Poor balance is a key risk factor for falls; therefore, the best measure of this variable should be selected when evaluating patients at risk of falling.

Accuracy of DXA scanning of the thoracic spine: cadaveric studies comparing BMC, areal BMD and geometric estimates of volumetric BMD against ash weight and CT measures of bone volume.

Biomechanical studies of the thoracic spine often scan cadaveric segments by dual energy X-ray absorptiometry (DXA) to obtain measures of bone mass. Only one study has reported the accuracy of lateral scans of thoracic vertebral bodies. The accuracy of DXA scans of thoracic spine segments and of anterior-posterior (AP) thoracic scans has not been investigated. We have examined the accuracy of AP and lateral thoracic DXA scans by comparison with ash weight, the gold-standard for measuring bone mineral content (BMC). We have also compared three methods of estimating volumetric bone mineral density (vBMD) with a novel standard-ash weight (g)/bone volume (cm3) as measured by computed tomography (CT). Twelve T5-T8 spine segments were scanned with DXA (AP and lateral) and CT. The T6 vertebrae were excised, the posterior elements removed and then the vertebral bodies were ashed in a muffle furnace. We proposed a new method of estimating vBMD and compared it with two previously published methods. BMC values from lateral DXA scans displayed the strongest correlation with ash weight (r=0.99) and were on average 12.8% higher (p<0.001). As expected, BMC (AP or lateral) was more strongly correlated with ash weight than areal bone mineral density (aBMD; AP: r=0.54, or lateral: r=0.71) or estimated vBMD. Estimates of vBMD with either of the three methods were strongly and similarly correlated with volumetric BMD calculated by dividing ash weight by CT-derived volume. These data suggest that readily available DXA scanning is an appropriate surrogate measure for thoracic spine bone mineral and that the lateral scan might be the scan method of choice.

Failure characteristics of the thoracic spine with a posteroanterior load: investigating the safety of spinal mobilization.

STUDY DESIGN: In vitro biomechanical study of human cadaveric thoracic spine segments and one intact cadaver and applied load measurements in human volunteers. OBJECTIVES: To quantify failure load and pattern of midthoracic vertebrae under a posteroanterior load and to compare failure load in vitro with applied load in vivo. SUMMARY OF BACKGROUND DATA: Osteoporosis and back pain are common alone and in combination among older adults. Spinal mobilization techniques have been shown to relieve back pain and improve function in various clinical settings. However, whether controlled spinal mobilization can cause vertebral fracture in individuals with osteoporosis is not known. METHODS: Twelve T5-T8 cadaveric specimens (mean age, 77 years) were scanned using bone densitometry, radiographed, and measured for bone size. The authors measured failure load, failure site, and intervertebral motion (using a precision optoelectronic camera system) when a posteroanterior load was applied at the spinous process of T6 using a servohydraulic material testing machine. Post-test radiography and CT scan were used to verify failure site. These tests were repeated in an intact cadaver using a Tekscan I-Scan sensor to measure applied loads. The authors also quantified in vivo applied loads during posteroanterior mobilization during seven trials by two experienced physiotherapists. RESULTS: Mean (SD) in vitro failure load of 479 N (162 N) was significantly higher than the mean (SD) in vivo applied load of 145 N (38 N) (P = 0.0004). Macroscopic observation revealed a fracture at the T6 spinous process in 11 specimens and one at the T7 spinous process. These fractures were detected by plain radiography in three of 12 cases and by CT scan in six of 12 cases. CONCLUSIONS: The results suggest a reasonable margin between failure load in vitro and applied mobilization load in vivo.