Detalhe da pesquisa
1.
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether.
Cell
; 179(1): 147-164.e20, 2019 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31539493
2.
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.
Cell
; 173(3): 720-734.e15, 2018 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29677515
3.
Regulation of membrane fluidity by RNF145-triggered degradation of the lipid hydrolase ADIPOR2.
EMBO J
; 41(19): e110777, 2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993436
4.
The liquid-to-solid transition of FUS is promoted by the condensate surface.
Proc Natl Acad Sci U S A
; 120(33): e2301366120, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37549257
5.
Genetic variants in the SHISA6 gene are associated with delayed cognitive impairment in two family datasets.
Alzheimers Dement
; 19(2): 611-620, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35490390
6.
Wild-type sTREM2 blocks Aß aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aß aggregation.
J Biol Chem
; 296: 100631, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33823153
7.
Amyloid-ß toxicity modulates tau phosphorylation through the PAX6 signalling pathway.
Brain
; 144(9): 2759-2770, 2021 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34428276
8.
Differential interaction with TREM2 modulates microglial uptake of modified Aß species.
Glia
; 69(12): 2917-2932, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34427354
9.
Inherited and Sporadic Amyotrophic Lateral Sclerosis and Fronto-Temporal Lobar Degenerations arising from Pathological Condensates of Phase Separating Proteins.
Hum Mol Genet
; 28(R2): R187-R196, 2019 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31595953
10.
Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer's-related mice.
Alzheimers Dement
; 17(2): 149-163, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33314529
11.
Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau.
Mol Psychiatry
; 24(9): 1383-1397, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30283031
12.
Heritability and genetic variance of dementia with Lewy bodies.
Neurobiol Dis
; 127: 492-501, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30953760
13.
APOE-ε4 associates with hippocampal volume, learning, and memory across the spectrum of Alzheimer's disease and dementia with Lewy bodies.
Alzheimers Dement
; 14(9): 1137-1147, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29782824
14.
ALS5/SPG11/KIAA1840 mutations cause autosomal recessive axonal Charcot-Marie-Tooth disease.
Brain
; 139(Pt 1): 73-85, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26556829
15.
Characterizing familial corticobasal syndrome due to Alzheimer's disease pathology and PSEN1 mutations.
Alzheimers Dement
; 13(5): 520-530, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27743520
16.
Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
Alzheimers Dement
; 13(7): 727-738, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28183528
17.
ATP-binding cassette transporter A7 (ABCA7) loss of function alters Alzheimer amyloid processing.
J Biol Chem
; 290(40): 24152-65, 2015 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26260791
18.
Withdrawal: Cytosolic proteins regulate α-synuclein dissociation from presynaptic membranes.
J Biol Chem
; 295(39): 13694, 2020 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32978332
19.
Hypermethylation of the CpG-island near the C9orf72 G4C2-repeat expansion in FTLD patients.
Hum Mol Genet
; 23(21): 5630-7, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24908669
20.
Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.
Hum Mol Genet
; 23(23): 6139-46, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24973356