Detalhe da pesquisa
1.
N-Methyl-3-(tetrahydro-2H-pyran-4-yl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamides as a novel class of cannabinoid receptors agonists with low CNS penetration.
Bioorg Med Chem Lett
; 22(12): 3884-9, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22607668
2.
γ-Carbolines: a novel class of cannabinoid agonists with high aqueous solubility and restricted CNS penetration.
Bioorg Med Chem Lett
; 22(4): 1619-24, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22284817
3.
Effector membrane translocation biosensors reveal G protein and ßarrestin coupling profiles of 100 therapeutically relevant GPCRs.
Elife
; 112022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35302493
4.
Molecular Mechanisms of Desensitization Underlying the Differential Effects of Formyl Peptide Receptor 2 Agonists on Cardiac Structure-Function Post Myocardial Infarction.
ACS Pharmacol Transl Sci
; 5(10): 892-906, 2022 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36268126
5.
In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure.
Circ Heart Fail
; 14(3): e007351, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33663236
6.
Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction.
JACC Basic Transl Sci
; 6(8): 676-689, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34466754
7.
N,N-Diethyl-4-[(3-hydroxyphenyl)(piperidin-4-yl)amino] benzamide derivatives: the development of diaryl amino piperidines as potent delta opioid receptor agonists with in vivo anti-nociceptive activity in rodent models.
Bioorg Med Chem Lett
; 19(21): 5994-8, 2009 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19800791
8.
Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment.
JACC Basic Transl Sci
; 4(8): 905-920, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31909300
9.
Novel benzimidazole derivatives as selective CB2 agonists.
Bioorg Med Chem Lett
; 18(13): 3695-700, 2008 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18522867
10.
Discovery of agonists of cannabinoid receptor 1 with restricted central nervous system penetration aimed for treatment of gastroesophageal reflux disease.
J Med Chem
; 56(1): 220-40, 2013 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23227781
11.
A peripherally restricted cannabinoid receptor agonist produces robust anti-nociceptive effects in rodent models of inflammatory and neuropathic pain.
Pain
; 151(2): 337-344, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20696525
12.
New 1,2,3,4-tetrahydropyrrolo[3,4-b]indole derivatives as selective CB2 receptor agonists.
Bioorg Med Chem Lett
; 17(22): 6183-7, 2007 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17884494