Detalhe da pesquisa
1.
Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study.
Hepatology
; 78(2): 397-415, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37386786
2.
Direct coculture of human pluripotent stem cell-derived cardiac progenitor cells with epicardial cells induces cardiomyocyte proliferation and reduces sarcomere organization.
J Mol Cell Cardiol
; 162: 144-157, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34560089
3.
A phase II, randomized, open-label, 52-week study of seladelpar in patients with primary biliary cholangitis.
J Hepatol
; 77(2): 353-364, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35367282
4.
Developmental lineage of human pluripotent stem cell-derived cardiac fibroblasts affects their functional phenotype.
FASEB J
; 35(9): e21799, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34339055
5.
Seladelpar improved measures of pruritus, sleep, and fatigue and decreased serum bile acids in patients with primary biliary cholangitis.
Liver Int
; 42(1): 112-123, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34403559
6.
Pharmacokinetics of AXA1665, a Novel Composition of Amino Acids, in Comparison With Protein Supplement: A Single-Dose, Open-Label, Randomized Study in Healthy Subjects.
Clin Pharmacol Drug Dev
; 12(7): 718-730, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36789635
7.
Advances in Manufacturing Cardiomyocytes from Human Pluripotent Stem Cells.
Annu Rev Chem Biomol Eng
; 13: 255-278, 2022 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35320695
8.
A guide to senolytic intervention in neurodegenerative disease.
Mech Ageing Dev
; 200: 111585, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34627838
9.
The Pharmacodynamics, Pharmacokinetics, and Safety of Arhalofenate in Combination with Febuxostat When Treating Hyperuricemia Associated with Gout.
J Rheumatol
; 44(3): 374-379, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27980008
10.
Seladelpar (MBX-8025), a selective PPAR-δ agonist, in patients with primary biliary cholangitis with an inadequate response to ursodeoxycholic acid: a double-blind, randomised, placebo-controlled, phase 2, proof-of-concept study.
Lancet Gastroenterol Hepatol
; 2(10): 716-726, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28818518
11.
A Randomized, Double-Blind, Active- and Placebo-Controlled Efficacy and Safety Study of Arhalofenate for Reducing Flare in Patients With Gout.
Arthritis Rheumatol
; 68(8): 2027-34, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26989892