Detalhe da pesquisa
1.
Use of toxicogenomics in drug safety evaluation: Current status and an industry perspective.
Regul Toxicol Pharmacol
; 96: 18-29, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29679677
2.
Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling.
Nucleic Acids Res
; 40(5): 1928-43, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22075993
3.
Real-World Safety and Effectiveness of Voretigene Neparvovec: Results up to 2 Years from the Prospective, Registry-Based PERCEIVE Study.
Biomolecules
; 14(1)2024 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38254722
4.
HIF mediated and DNA damage independent histone H2AX phosphorylation in chronic hypoxia.
Biol Chem
; 394(4): 519-28, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23241668
5.
Vitamin C is dispensable for oxygen sensing in vivo.
Blood
; 117(20): 5485-93, 2011 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21346252
6.
Congenital erythrocytosis associated with gain-of-function HIF2A gene mutations and erythropoietin levels in the normal range.
Haematologica
; 98(10): 1624-32, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23716564
7.
Endogenous myoglobin in breast cancer is hypoxia-inducible by alternative transcription and functions to impair mitochondrial activity: a role in tumor suppression?
J Biol Chem
; 286(50): 43417-28, 2011 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21930697
8.
Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events.
Proc Natl Acad Sci U S A
; 106(33): 14004-9, 2009 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19666490
9.
Human nephrosclerosis triggers a hypoxia-related glomerulopathy.
Am J Pathol
; 176(2): 594-607, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20019191
10.
2-year outcomes of ranibizumab versus laser therapy for the treatment of very low birthweight infants with retinopathy of prematurity (RAINBOW extension study): prospective follow-up of an open label, randomised controlled trial.
Lancet Child Adolesc Health
; 5(10): 698-707, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34391532
11.
The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability.
Mol Cell Biol
; 27(10): 3758-68, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17353276
12.
Histone deacetylase inhibitors synergize p300 autoacetylation that regulates its transactivation activity and complex formation.
Cancer Res
; 67(5): 2256-2264, 2007 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17332356
13.
Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1 alpha-deficient mouse embryonic fibroblasts.
Carcinogenesis
; 29(12): 2306-16, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18842680
14.
Regulated function of the prolyl-4-hydroxylase domain (PHD) oxygen sensor proteins.
Antioxid Redox Signal
; 9(9): 1329-38, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17627474
15.
Determination and modulation of prolyl-4-hydroxylase domain oxygen sensor activity.
Methods Enzymol
; 435: 43-60, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17998048
16.
Induction of the hypoxia-inducible factor system by low levels of heat shock protein 90 inhibitors.
Cancer Res
; 65(23): 11094-100, 2005 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16322259
17.
The Utility of Gene Expression Profiling from Tissue Samples to Support Drug Safety Assessments.
ILAR J
; 58(1): 69-79, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28575330
18.
Integration of oxygen signaling at the consensus HRE.
Sci STKE
; 2005(306): re12, 2005 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16234508
19.
Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element.
Biochem J
; 387(Pt 3): 711-7, 2005 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15563275
20.
Controlled Mycobacterium tuberculosis infection in mice under treatment with anti-IL-17A or IL-17F antibodies, in contrast to TNFα neutralization.
Sci Rep
; 6: 36923, 2016 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27853279