Detalhe da pesquisa
1.
Impaired Autophagic-Lysosomal Fusion in Parkinson's Patient Midbrain Neurons Occurs through Loss of ykt6 and Is Rescued by Farnesyltransferase Inhibition.
J Neurosci
; 43(14): 2615-2629, 2023 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36788031
2.
Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease.
N Engl J Med
; 381(17): 1644-1652, 2019 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31597037
3.
Molecular mechanisms of α-synuclein and GBA1 in Parkinson's disease.
Cell Tissue Res
; 373(1): 51-60, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29064079
4.
Honokiol decreases alpha-synuclein mRNA levels and reveals novel targets for modulating alpha-synuclein expression.
Front Aging Neurosci
; 15: 1179086, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37637959
5.
Rescue of α-synuclein aggregation in Parkinson's patient neurons by synergistic enhancement of ER proteostasis and protein trafficking.
Neuron
; 110(3): 436-451.e11, 2022 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34793693
6.
Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models.
Autophagy
; 18(5): 1127-1151, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35287553
7.
Detection of pathological alpha-synuclein aggregates in human iPSC-derived neurons and tissue.
STAR Protoc
; 2(1): 100372, 2021 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33733241
8.
Enhanced Hyaluronan Signaling and Autophagy Dysfunction by VPS35 D620N.
Neuroscience
; 441: 33-45, 2020 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32540366
9.
Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide.
Neuron
; 97(1): 92-107.e10, 2018 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29290548
10.
Nestin-positive/SOX2-negative cells mediate adult neurogenesis of nigral dopaminergic neurons in mice.
Neurosci Lett
; 615: 50-4, 2016 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26806039
11.
Parkinson's disease and enhanced inflammatory response.
Exp Biol Med (Maywood)
; 240(11): 1387-95, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25769314