Detalhe da pesquisa
1.
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1ß in type 2 diabetes.
Nat Immunol
; 11(10): 897-904, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20835230
2.
Matrix metalloproteinase-9 reduces islet amyloid formation by degrading islet amyloid polypeptide.
J Biol Chem
; 288(5): 3553-9, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23229548
3.
One year of sitagliptin treatment protects against islet amyloid-associated ß-cell loss and does not induce pancreatitis or pancreatic neoplasia in mice.
Am J Physiol Endocrinol Metab
; 305(4): E475-84, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23736544
4.
ß-cell loss and ß-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition.
Am J Pathol
; 178(6): 2632-40, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21641386
5.
Neprilysin impedes islet amyloid formation by inhibition of fibril formation rather than peptide degradation.
J Biol Chem
; 285(24): 18177-83, 2010 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20400513