Is nocturnal enuresis a predisposing factor for the overactive bladder?

Background/aim: This study aimed to perform a limited observational study to ascertain whether there is statistical support that nocturnal enuresis (NE) is a predisposing factor in the development of overactive bladder (OAB). Materials and methods: The authors recruited patients diagnosed with OAB over a period of twelve months, and those who declared a history of NE were asked additional questions regarding the features of their NE. Results: A total of 285 patients were diagnosed with overactive bladder, and 98 (34.38%) of them had previously displayed NE symptoms that had diminished before reaching the median age of 9.83. Separation of patients by sex revealed a male majority (58.16%). Additionally, most patients had urban origins (75.51%). The median time span from remission of NE to diagnosis of OAB was 24.79 years, and the median age at which patients began to suffer was 31.80 years. Behavioral factors (smoking, alcohol consumption) and psychological and infectious factors (past history of urinary tract infection) were identified at varying degrees. Conclusion: The presence of NE in a third of the patients who developed over time OAB and the earlier onset of OAB for these patients suggests a causal physiopathological relationship between NE and OAB. The preponderance of urban patients confirms the existence of acquired urban triggering factors of OAB (nutritious, social, or professional).

Urothelial Bladder Carcinoma in Students at a Dental Technical College: A Report of 3 Cases.

Bladder cancer is one of the main types of neoplasia affecting men, with the highest incidence reported toward the end of the seventh decade of life. Unlike other malignancies, bladder cancer is attributable to specific widely occurring carcinogenic risk factors in 60-70% of cases, and numerous professions have been linked to higher rates of the disease. The present study includes the cases of three male graduates (mean age, 23 years) from the same dental technical college, two of whom were students at the Faculty of Dental Medicine of the Iași University of Medicine and Pharmacy (Iași, Romania) at the time of diagnosis. The individuals were occupationally exposed for a mean of 43.66 months. Histopathological examinations following resection indicated the presence of benign lesions (1 case) and malignant lesions of low aggressiveness (2 cases). The patients' outcomes were favorable, and there was no tumor recurrence over a mean observation period of 56 months. The aim of the present study was to highlight the young age at which these patients developed bladder tumors under similar etiological conditions and over short periods of exposure to known occupational risk factors. This shorter time of exposure to risk factors makes it even harder to establish causality with the occurrence of bladder tumors. However, the present cases could lead to a suspicion of a direct association between the exposure and the tumors or an entirely coincidental occurrence.

Bacillus Calmette-Guérin therapy-associated granulomatous prostatitis mimicking prostate cancer on MRI: A case report and literature review.

Granulomatous prostatitis following bacillus Calmette-Guérin (BCG) immunotherapy is a well-known pathological entity, developing following initiation of BCG therapy as a prophylactic measure against the recurrence of non-muscle invasive bladder cancer. In addition, there are certain imaging similarities between granulomatous prostatitis and prostate cancer, including hypoechoic area on transrectal ultrasonography and low T2 signal intensity in some prostate areas on magnetic resonance imaging (MRI). This is the report of a case exhibiting a perfect imaging cross-match between granulomatous prostatitis and potential prostate cancer on repeated MRI exams, adding two supplementary aspects to the already known similarities, namely progressive restricted diffusion and increased contrast enhancement, which are specific to prostate cancer.