Detalhe da pesquisa
1.
AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress.
Blood
; 125(13): 2120-30, 2015 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25631767
2.
A classification system for clinical relevance of somatic variants identified in molecular profiling of cancer.
Genet Med
; 18(2): 128-36, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25880439
3.
Carnitine transporter CT2 (SLC22A16) is over-expressed in acute myeloid leukemia (AML) and target knockdown reduces growth and viability of AML cells.
Apoptosis
; 20(8): 1099-108, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25998464
4.
Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells.
Apoptosis
; 20(7): 948-59, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25832785
5.
Distinct patterns of clonal evolution in patients with concurrent myelo- and lymphoproliferative neoplasms.
Blood
; 132(20): 2201-2205, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30249785
6.
A randomized phase II study of cediranib alone versus cediranib in combination with dasatinib in docetaxel resistant, castration resistant prostate cancer patients.
Invest New Drugs
; 32(5): 1005-16, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24788563
7.
New sources of drugs for hematologic malignancies.
Blood
; 117(25): 6747-55, 2011 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21511957
8.
An international consensus on effective, inclusive, and career-spanning short-format training in the life sciences and beyond.
PLoS One
; 18(11): e0293879, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37943810
9.
The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma.
Blood
; 115(23): 4824-33, 2010 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20348394
10.
The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells.
Blood
; 116(18): 3593-603, 2010 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-20644115
11.
Design, synthesis, and in vitro characterization of novel hybrid peptidomimetic inhibitors of STAT3 protein.
Bioorg Med Chem
; 19(5): 1823-38, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21216604
12.
Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma.
Mol Cancer
; 9: 238, 2010 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20831814
13.
Assessing the Diagnostic Yield of Targeted Next-Generation Sequencing for Melanoma and Gastrointestinal Tumors.
J Mol Diagn
; 22(4): 467-475, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32036084
14.
Latency and interval therapy affect the evolution in metastatic colorectal cancer.
Sci Rep
; 10(1): 581, 2020 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31953485
15.
Somatic Tumor Variant Filtration Strategies to Optimize Tumor-Only Molecular Profiling Using Targeted Next-Generation Sequencing Panels.
J Mol Diagn
; 21(2): 261-273, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30576869
16.
Improving validation methods for molecular diagnostics: application of Bland-Altman, Deming and simple linear regression analyses in assay comparison and evaluation for next-generation sequencing.
J Clin Pathol
; 71(2): 117-124, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28747393
17.
Minimally Invasive Real-Time Detection of Actionable Mutations in Patients With Metastatic Solid Tumors Using Fine-Needle and Liquid Biopsies.
JCO Precis Oncol
; 2: 1-20, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35135130
18.
Integration of Technical, Bioinformatic, and Variant Assessment Approaches in the Validation of a Targeted Next-Generation Sequencing Panel for Myeloid Malignancies.
Arch Pathol Lab Med
; 141(6): 759-775, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28557600
19.
Comparison of Next-Generation Sequencing Panels and Platforms for Detection and Verification of Somatic Tumor Variants for Clinical Diagnostics.
J Mol Diagn
; 18(6): 842-850, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27770852
20.
Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial.
Genome Med
; 8(1): 109, 2016 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27782854