Detalhe da pesquisa
1.
Toll-like receptors TLR2 and TLR4 block the replication of pancreatic ß cells in diet-induced obesity.
Nat Immunol
; 20(6): 677-686, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31110312
2.
The orphan nuclear receptor SHP regulates ER stress response by inhibiting XBP1s degradation.
Genes Dev
; 33(15-16): 1083-1094, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31296559
3.
Hepatic SEL1L-HRD1 ER-associated degradation regulates systemic iron homeostasis via ceruloplasmin.
Proc Natl Acad Sci U S A
; 120(2): e2212644120, 2023 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36595688
4.
Cellular abundance of sodium phosphate cotransporter SLC20A1/PiT1 and phosphate uptake are controlled post-transcriptionally by ESCRT.
J Biol Chem
; 298(6): 101945, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35447110
5.
Hepatic Sel1L-Hrd1 ER-associated degradation (ERAD) manages FGF21 levels and systemic metabolism via CREBH.
EMBO J
; 37(22)2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30389665
6.
ER-associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity.
Blood
; 136(26): 2975-2986, 2020 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33150381
7.
High-Resolution Metabolomics with Acyl-CoA Profiling Reveals Widespread Remodeling in Response to Diet.
Mol Cell Proteomics
; 14(6): 1489-500, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25795660
8.
Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival.
Proc Natl Acad Sci U S A
; 111(5): E582-91, 2014 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24453213
9.
Genetic Screening of Haploid Neural Stem Cells Reveals that Nfkbia and Atp2b4 are Key Regulators of Oxidative Stress in Neural Precursors.
Adv Sci (Weinh)
; : e2309292, 2024 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38666459
10.
Proteomic screens of SEL1L-HRD1 ER-associated degradation substrates reveal its role in glycosylphosphatidylinositol-anchored protein biogenesis.
Nat Commun
; 15(1): 659, 2024 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38253565
11.
SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex.
Nat Commun
; 15(1): 1440, 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38365914
12.
Hypomorphic variants of SEL1L-HRD1 ER-associated degradation are associated with neurodevelopmental disorders.
J Clin Invest
; 134(2)2024 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37943610
13.
Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4.
J Biol Chem
; 287(29): 24378-86, 2012 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22645141
14.
Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity.
J Biol Chem
; 287(17): 13561-71, 2012 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22396530
15.
Mechanisms of inflammatory responses in obese adipose tissue.
Annu Rev Nutr
; 32: 261-86, 2012 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22404118
16.
BCL2 is a major regulator of haploidy maintenance in murine embryonic stem cells.
Cell Prolif
; 56(12): e13498, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37144356
17.
SEL1L-HRD1 interaction is prerequisite for the formation of a functional HRD1 ERAD complex.
bioRxiv
; 2023 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37333389
18.
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
Nat Commun
; 14(1): 3132, 2023 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37253728
19.
Haploid-genetic screening of trophectoderm specification identifies Dyrk1a as a repressor of totipotent-like status.
Sci Adv
; 9(51): eadi5683, 2023 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38117886
20.
Rif1 and Hmgn3 regulate the conversion of murine trophoblast stem cells.
Cell Rep
; 38(13): 110570, 2022 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35354046