Ultrafast thin-disk multi-pass amplifier system providing 1.9 kW of average output power and pulse energies in the 10 mJ range at 1 ps of pulse duration for glass-cleaving applications.

An ultrafast Yb-doped thin-disk multi-pass laser amplifier system with flexible parameters for material processing is reported. We can generate bursts consisting of four pulses at a distance of 20 ns and a total energy of 46.7 mJ at a repetition rate of 25 kHz. In single-pulse operation, 1.5 kW of average output is achieved at 400 kHz when optimizing for a beam quality of M2 = 1.5. Alignment for maximum output power provides 1.9 kW at the same repetition rate. All results are obtained without chirped-pulse amplification in the multi-pass set-up. The application potential of the system is demonstrated exploring its performance in materials processing of dielectrics. Cleaving of 3.8-mm-thick SCHOTT borofloat glass with a velocity of 1200 mm/s is demonstrated with 300 W of input power. Single-pass modification of 30 mm borosilicate glass is enabled with a Bessel beam at 1 kW of average power delivered by four-pulse bursts of an energy of 30 mJ.

Kerr-lens mode-locked thin-disk oscillator with 50% output coupling rate.

Several approaches to power scaling of mode-locked thin-disk oscillators exist. One of these approaches is based on the increased gain provided by multiple passes through the thin-disk laser medium. For the first time, to the best of our knowledge, we applied this approach to a Kerr-lens mode-locked thin-disk oscillator. The so obtained additional gain allowed mode-locked operation with up to 50% output coupling rate. This first demonstration is of particular importance for gain media with inherently low-emission cross sections and paves the way to even more powerful Kerr-lens mode-locked thin-disk oscillators. Moreover, the experimental results indicate an increased self-amplitude modulation related to an overall increase in the soft-aperture Kerr-lens effect.

1 kW, 200 mJ picosecond thin-disk laser system.

We report on a laser system based on thin-disk technology and chirped pulse amplification, providing output pulse energies of 200 mJ at a 5 kHz repetition rate. The amplifier contains a ring-type cavity and two thin Yb:YAG disks, each pumped by diode laser systems providing up to 3.5 kW power at a 969 nm wavelength. The average output power of more than 1 kW is delivered in an excellent output beam characterized by M2=1.1. The output pulses are compressed to 1.1 ps at full power with a pair of dielectric gratings.

Powerful 100-fs-scale Kerr-lens mode-locked thin-disk oscillator.

We have recently demonstrated a simple power scaling procedure for Kerr-lens mode-locked thin-disk oscillators. Here we report on the extension of this scheme to a broadband high-peak-power thin-disk oscillator, delivering 140-fs pulses with a peak and average power of 62 MW and 155 W, respectively. This result shows that reaching the emission bandwidth of the gain material in Kerr-lens mode-locked thin-disk oscillators is feasible without sacrificing output power, efficiency, or stability by relying on high intracavity nonlinearities.

Direct regenerative amplification of femtosecond pulses to the multimillijoule level.

We present a compact femtosecond nonlinear Yb:YAG thin-disk regenerative amplifier delivering pulses carried at a wavelength of 1030 nm with an average power of >200 W at a repetition rate of 100 kHz and an energy noise value of 0.46% (rms) in a beam with a propagation factor of M2<1.4. The amplifier is seeded with bandwidth-limited subpicosecond pulses without temporal stretching. We give estimates for the nonlinear parameters influencing the system and show that chirped mirrors compress the 2 mJ pulses to a near-bandwidth-limited duration of 210 fs.

Ultrafast thin-disk multipass laser amplifier delivering 1.4 kW (4.7 mJ, 1030 nm) average power converted to 820 W at 515 nm and 234 W at 343 nm.

We report on an Yb:YAG thin-disk multipass laser amplifier delivering sub-8 ps pulses at a wavelength of 1030 nm with 1420 W of average output power and 4.7 mJ of pulse energy. The amplifier is seeded by a regenerative amplifier delivering 6.5 ps pulses with 300 kHz of repetition rate and an average power of 115 W. The optical efficiency of the multipass amplifier was measured to be 48% and the beam quality factor was better than M2 = 1.4. Furthermore we report on the external second harmonic generation from 1030 nm to 515 nm using an LBO crystal leading to an output power of 820 W with 2.7 mJ of energy per pulse. This corresponds to a conversion efficiency of 70%. Additionally, 234 W of average power were obtained at the third harmonic with a wavelength of 343 nm.

260-megahertz, megawatt-level thin-disk oscillator.

A Kerr-lens mode-locked (KLM) Yb:YAG thin-disk oscillator delivering 215-fs pulses with 75-W average power and 1.4-MW peak power at a repetition rate of 260 MHz is presented. Self-starting KLM is demonstrated at an output power of 68 W. This is the highest repetition rate of any mode-locked thin-disk oscillators so far. Concepts for scaling the repetition rate up to 1 GHz are discussed.

Energy scaling of Kerr-lens mode-locked thin-disk oscillators.

Geometric scaling of a Kerr-lens mode-locked Yb:YAG thin-disk oscillator yields femtosecond pulses with an average output power of 270 W. The scaled system delivers femtosecond (210-330 fs) pulses with a peak power of 38 MW. These values of average and peak power surpass the performance of any previously reported femtosecond laser oscillator operated in atmospheric air.

1.1 kW average output power from a thin-disk multipass amplifier for ultrashort laser pulses.

We report on a thin-disk multipass amplifier for ultrashort laser pulses delivering an average output power of 1105 W. The amplifier was seeded by a Trumpf TruMicro5050 laser with a power of 80 W at a wavelength of 1030 nm, pulse duration of 6.5 ps, and repetition rate of 800 kHz. The energy of the amplified pulses is 1.38 mJ with a duration of 7.3 ps. The amplifier exhibits an optical efficiency of 44% and a slope efficiency of 46%. The beam quality was measured to be better than M²=1.25.

Mode-locked Yb:YAG thin-disk oscillator with 41 µJ pulse energy at 145 W average infrared power and high power frequency conversion.

We demonstrate the generation of 1.1 ps pulses containing more than 41 µJ of energy directly out of an Yb:YAG thin-disk without any additional amplification stages. The laser oscillator operates in ambient atmosphere with a 3.5 MHz repetition rate and 145 W of average output power at a fundamental wavelength of 1030 nm. An average output power of 91.5 W at 515 nm was obtained by frequency doubling with a conversion efficiency exceeding 65%. Third harmonic generation resulted in 34 W at 343 nm at 34% efficiency.

Subpicosecond thin-disk laser oscillator with pulse energies of up to 25.9 microjoules by use of an active multipass geometry.

The pulse shaping dynamics of a diode-pumped laser oscillator with active multipass cell was studied experimentally and numerically. We demonstrate the generation of high energy subpicosecond pulses with a pulse energy of up to 25.9 microJ at a pulse duration of 928 fs directly from a thin-disk laser oscillator. These results are achieved by employing a selfimaging active multipass geometry operated in ambient atmosphere. Stable single pulse operation has been obtained with an average output power in excess of 76 W and at a repetition rate of 2.93 MHz. Self starting passive mode locking was accomplished using a semiconductor saturable absorber mirror. The experimental results are compared with numerical simulations, showing good agreement including the appearance of Kelly sidebands. Furthermore, a modified soliton-area theorem for approximating the pulse duration is presented.

Multi-mW, few-cycle mid-infrared continuum spanning from 500 to 2250 cm-1.

The demand for and usage of broadband coherent mid-infrared sources, such as those provided by synchrotron facilities, are growing. Since most organic molecules exhibit characteristic vibrational modes in the wavelength range between 500 and 4000 cm-1, such broadband coherent sources enable micro- or even nano-spectroscopic applications at or below the diffraction limit with a high signal-to-noise ratio1, 2, 3. These techniques have been applied in diverse fields ranging from life sciences, material analysis, and time-resolved spectroscopy. Here we demonstrate a broadband, coherent and intrinsically carrier-envelope-phase-stable source with a spectrum spanning from 500 to 2250 cm-1 (-30 dB) at an average power of 24 mW and a repetition rate of 77 MHz. This performance is enabled by the first mode-locked thin-disk oscillator operating at 2 µm wavelength, providing a tenfold increase in average power over femtosecond oscillators previously demonstrated in this wavelength range4. Multi-octave spectral coverage from this compact and power-scalable system opens up a range of time- and frequency-domain spectroscopic applications.

High-repetition-rate picosecond pump laser based on a Yb:YAG disk amplifier for optical parametric amplification.

We report an optically synchronized picosecond pump laser for optical parametric amplifiers based on an Yb:YAG thin-disk amplifier. At 3 kHz repetition rate, pulse energies of 25 mJ with 1.6 ps pulse duration were achieved with an rms fluctuation in pulse energy of <0.7% by utilizing a broadly intermittent single-energy regime in the deterministic chaos of a continuously pumped regenerative amplifier.

Passively mode-locked Yb:YAG thin-disk laser with pulse energies exceeding 13 microJ by use of an active multipass geometry.

We demonstrate the generation of high-energy picosecond pulses directly from a thin-disk laser oscillator by employing a self-imaging active multipass geometry. Stable single-pulse operation has been obtained with an average output power in excess of 50 W, excluding a cw background of 8%, at a repetition rate of 3.8 MHz. Self-starting passive mode locking was accomplished using a semiconductor saturable absorber mirror. The maximum pulse energy was 13.4 microJ at a pulse duration of 1.36 ps with a time-bandwidth product of 0.34. Single-pass external frequency doubling with a conversion efficiency of 60% yielded >28 W of average power at 515 nm.

Impaired transporter associated with antigen processing (TAP) function attributable to a single amino acid alteration in the peptide TAP subunit TAP1.

The heterodimeric peptide transporter TAP belongs to the ABC transporter family. Sequence comparisons with the P-glycoprotein and cystic fibrosis transmembrane conductance regulator and the functional properties of selective amino acids in these ABC transporters postulated that the glutamic acid at position 263 and the phenylalanine at position 265 of the TAP1 subunit could affect peptide transporter function. To define the role of both amino acids, TAP1 mutants containing a deletion or a substitution to alanine at position 263 or 265 were generated and stably expressed in murine and human TAP1(-/-) cells. The different TAP1 mutants were characterized in terms of expression and function of TAP, MHC class I surface expression, immune recognition, and species-specific differences. The phenotype of murine and human cells expressing human TAP1 mutants with a deletion or substitution of Glu(263) was comparable to that of TAP1(-/-) cells. In contrast, murine and human TAP1 mutant cells containing a deletion or mutation of Phe(265) of the TAP1 subunit exhibit wild-type TAP function. This was associated with high levels of MHC class I surface expression and recognition by specific CTL, which was comparable to that of wild-type TAP1-transfected control cells. Thus, biochemical and functional evidence is presented that the Glu(263) of the TAP1 protein, but not the Phe(265), is critical for proper TAP function.