Detalhe da pesquisa
1.
The role of cysteines in the structure and function of OGG1.
J Biol Chem
; 296: 100093, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33203705
2.
Mutational signature profiling classifies subtypes of clinically different mismatch-repair-deficient tumours with a differential immunogenic response potential.
Br J Cancer
; 126(11): 1595-1603, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35197584
3.
Cost-Effectiveness and Economic Burden Analyses on All First-Line Treatments of Chronic Lymphocytic Leukemia.
Value Health
; 25(10): 1685-1695, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35537984
4.
Molecular and structural characterization of oxidized ribonucleotide insertion into DNA by human DNA polymerase ß.
J Biol Chem
; 295(6): 1613-1622, 2020 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31892517
5.
Using single-molecule FRET to probe the nucleotide-dependent conformational landscape of polymerase ß-DNA complexes.
J Biol Chem
; 295(27): 9012-9020, 2020 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32385112
6.
Survival trends in chronic lymphocytic leukemia across treatment eras: US SEER database analysis (1985-2017).
Ann Hematol
; 100(10): 2501-2512, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34279676
7.
A pre-catalytic non-covalent step governs DNA polymerase ß fidelity.
Nucleic Acids Res
; 47(22): 11839-11849, 2019 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31732732
8.
Revealing an Internal Stabilization Deficiency in the DNA Polymerase ß K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography.
Biochemistry
; 59(8): 955-963, 2020 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31999437
9.
The double-edged sword of cancer mutations: exploiting neoepitopes for the fight against cancer.
Mutagenesis
; 35(1): 69-78, 2020 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31880305
10.
DNA polymerase beta participates in DNA End-joining.
Nucleic Acids Res
; 46(1): 242-255, 2018 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29161447
11.
I260Q DNA polymerase ß highlights precatalytic conformational rearrangements critical for fidelity.
Nucleic Acids Res
; 46(20): 10740-10756, 2018 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30239932
12.
The nature of the DNA substrate influences pre-catalytic conformational changes of DNA polymerase ß.
J Biol Chem
; 293(39): 15084-15094, 2018 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30068550
13.
The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype.
PLoS Genet
; 12(8): e1006208, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27513445
14.
Probing DNA Base-Dependent Leaving Group Kinetic Effects on the DNA Polymerase Transition State.
Biochemistry
; 57(26): 3925-3933, 2018 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29889506
15.
Heterozygosity for a hypomorphic Polß mutation reduces the expansion frequency in a mouse model of the Fragile X-related disorders.
PLoS Genet
; 11(4): e1005181, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25886163
16.
A Change in the Rate-Determining Step of Polymerization by the K289M DNA Polymerase ß Cancer-Associated Variant.
Biochemistry
; 56(15): 2096-2105, 2017 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28326765
17.
Remote Mutations Induce Functional Changes in Active Site Residues of Human DNA Polymerase ß.
Biochemistry
; 56(18): 2363-2371, 2017 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28402631
18.
Defective Nucleotide Release by DNA Polymerase ß Mutator Variant E288K Is the Basis of Its Low Fidelity.
Biochemistry
; 56(41): 5550-5559, 2017 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28945359
19.
DNA Polymerase ß Cancer-Associated Variant I260M Exhibits Nonspecific Selectivity toward the ß-γ Bridging Group of the Incoming dNTP.
Biochemistry
; 56(40): 5449-5456, 2017 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28862868
20.
Tumor-associated mutations in a conserved structural motif alter physical and biochemical properties of human RAD51 recombinase.
Nucleic Acids Res
; 43(2): 1098-111, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25539919