Detalhe da pesquisa
1.
ThermoBRET: A Ligand-Engagement Nanoscale Thermostability Assay Applied to GPCRs.
Chembiochem
; 25(2): e202300459, 2024 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37872746
2.
Accuracy of routine external ventricular drain placement following a mixed reality-guided twist-drill craniostomy.
Neurosurg Focus
; 56(1): E11, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38163351
3.
Platform Reagents Enable Synthesis of Ligand-Directed Covalent Probes: Study of Cannabinoid Receptor 2 in Live Cells.
J Am Chem Soc
; 145(28): 15094-15108, 2023 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37401816
4.
How dimensions can guide surgical planning and training: a systematic review of Kambin's triangle.
Neurosurg Focus
; 54(1): E6, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36587400
5.
Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs.
Nat Chem Biol
; 16(3): 240-249, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32080630
6.
Spine surgery under awake spinal anesthesia: an Egyptian experience during the COVID-19 pandemic.
Neurosurg Focus
; 51(6): E6, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34852322
7.
Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells.
J Am Chem Soc
; 142(40): 16953-16964, 2020 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32902974
8.
Investigating the Influence of Tracer Kinetics on Competition-Kinetic Association Binding Assays: Identifying the Optimal Conditions for Assessing the Kinetics of Low-Affinity Compounds.
Mol Pharmacol
; 96(3): 378-392, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31436538
9.
Pharmacological Characterization of a Novel 5-Hydroxybenzothiazolone-Derived ß 2-Adrenoceptor Agonist with Functional Selectivity for Anabolic Effects on Skeletal Muscle Resulting in a Wider Cardiovascular Safety Window in Preclinical Studies.
J Pharmacol Exp Ther
; 369(2): 188-199, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30819762
10.
Fevipiprant (QAW039), a Slowly Dissociating CRTh2 Antagonist with the Potential for Improved Clinical Efficacy.
Mol Pharmacol
; 89(5): 593-605, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26916831
11.
Long Receptor Residence Time of C26 Contributes to Super Agonist Activity at the Human ß2 Adrenoceptor.
Mol Pharmacol
; 89(4): 467-75, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26772612
12.
Comparing the cardiovascular therapeutic indices of glycopyrronium and tiotropium in an integrated rat pharmacokinetic, pharmacodynamic and safety model.
Toxicol Appl Pharmacol
; 287(1): 9-16, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26026369
13.
Observed drug-receptor association rates are governed by membrane affinity: the importance of establishing "micro-pharmacokinetic/pharmacodynamic relationships" at the ß2-adrenoceptor.
Mol Pharmacol
; 85(4): 608-17, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24476583
14.
Early Experience with Prone Lateral Interbody Fusion in Deformity Correction: A Single-Institution Experience.
J Clin Med
; 13(8)2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38673552
15.
Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists.
ACS Cent Sci
; 10(5): 956-968, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38799662
16.
A 13-Year-Old Girl With Unilateral Visual Changes.
J Investig Med High Impact Case Rep
; 11: 23247096221150635, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36738077
17.
Novel Merging of CT and MRI to Allow for Safe Navigation into Kambin's Triangle for Percutaneous Lumbar Interbody Fusion-Initial Case Series Investigating Safety and Efficacy.
Oper Neurosurg (Hagerstown)
; 24(3): 331-340, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36701664
18.
Development of a membrane-based Gi-CASE biosensor assay for profiling compounds at cannabinoid receptors.
Front Pharmacol
; 14: 1158091, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37637423
19.
Associations between urbanicity and spinal cord astrocytoma management and outcomes.
Cancer Epidemiol
; 86: 102431, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37478632
20.
Two-Year Clinical and Radiographic Outcomes for Percutaneous Lumbar Interbody Fusion With an Expandable Titanium Cage Through Kambin's Triangle Without Facetectomy.
Int J Spine Surg
; 17(6): 760-770, 2023 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37553259