Detalhe da pesquisa
1.
Computational drug repurposing against SARS-CoV-2 reveals plasma membrane cholesterol depletion as key factor of antiviral drug activity.
PLoS Comput Biol
; 18(4): e1010021, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35404937
2.
An Unexpected Enzyme in Vascular Smooth Muscle Cells: Angiotensin II Upregulates Cholesterol-25-Hydroxylase Gene Expression.
Int J Mol Sci
; 24(4)2023 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36835391
3.
Signatures of cell death and proliferation in perturbation transcriptomics data-from confounding factor to effective prediction.
Nucleic Acids Res
; 47(19): 10010-10026, 2019 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31552418
4.
Cannabinoid receptor type 1 (CB1R) inhibits hypothalamic leptin signaling via ß-arrestin1 in complex with TC-PTP and STAT3.
iScience
; 26(7): 107207, 2023 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37534180
5.
Patient-specific Boolean models of signalling networks guide personalised treatments.
Elife
; 112022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164900
6.
Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data.
Nat Commun
; 13(1): 3224, 2022 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35680885
7.
A community challenge for a pancancer drug mechanism of action inference from perturbational profile data.
Cell Rep Med
; 3(1): 100492, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35106508
8.
Modeling in systems biology: Causal understanding before prediction?
Patterns (N Y)
; 2(6): 100280, 2021 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34179849
9.
Characterization of Type 1 Angiotensin II Receptor Activation Induced Dual-Specificity MAPK Phosphatase Gene Expression Changes in Rat Vascular Smooth Muscle Cells.
Cells
; 10(12)2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34944046
10.
Why do pathway methods work better than they should?
FEBS Lett
; 594(24): 4189-4200, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33270910
11.
Transfer of regulatory knowledge from human to mouse for functional genomics analysis.
Biochim Biophys Acta Gene Regul Mech
; 1863(6): 194431, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31525460
12.
Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data.
Genome Biol
; 21(1): 36, 2020 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32051003
13.
Inferring clonal composition from multiple tumor biopsies.
NPJ Syst Biol Appl
; 6(1): 27, 2020 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32843649
14.
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.
Nat Commun
; 10(1): 2674, 2019 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31209238
15.
Angiotensin type 1A receptor regulates ß-arrestin binding of the ß2-adrenergic receptor via heterodimerization.
Mol Cell Endocrinol
; 442: 113-124, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27908837
16.
Predicting human olfactory perception from chemical features of odor molecules.
Science
; 355(6327): 820-826, 2017 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28219971
17.
Correction: Improved Methodical Approach for Quantitative BRET Analysis of G Protein Coupled Receptor Dimerization.
PLoS One
; 11(5): e0156824, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27243812
18.
Improved methodical approach for quantitative BRET analysis of G Protein Coupled Receptor dimerization.
PLoS One
; 9(10): e109503, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25329164
19.
Allosteric interactions within the AT1 angiotensin receptor homodimer: role of the conserved DRY motif.
Biochem Pharmacol
; 84(4): 477-85, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22579851
20.
Mechanisms of angiotensin II-mediated regulation of aldosterone synthase expression in H295R human adrenocortical and rat adrenal glomerulosa cells.
Mol Cell Endocrinol
; 302(2): 244-53, 2009 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-19418629