Detalhe da pesquisa
1.
Short-range translocation by a restriction enzyme motor triggers diffusion along DNA.
Nat Chem Biol
; 2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38167920
2.
CRISPR-Cas12a-mediated DNA clamping triggers target-strand cleavage.
Nat Chem Biol
; 18(9): 1014-1022, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35836018
3.
ENDO-Pore: high-throughput linked-end mapping of single DNA cleavage events using nanopore sequencing.
Nucleic Acids Res
; 49(20): e118, 2021 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34417616
4.
Mitochondrial import, health and mtDNA copy number variability seen when using type II and type V CRISPR effectors.
J Cell Sci
; 133(18)2020 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32843580
5.
5' modifications to CRISPR-Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage.
Nucleic Acids Res
; 48(12): 6811-6823, 2020 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32496535
6.
Hexameric assembly of the AAA+ protein McrB is necessary for GTPase activity.
Nucleic Acids Res
; 47(2): 868-882, 2019 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30521042
7.
The H-subunit of the restriction endonuclease CglI contains a prototype DEAD-Z1 helicase-like motor.
Nucleic Acids Res
; 46(5): 2560-2572, 2018 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29471489
8.
CgII cleaves DNA using a mechanism distinct from other ATP-dependent restriction endonucleases.
Nucleic Acids Res
; 45(14): 8435-8447, 2017 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28854738
9.
Length heterogeneity at conserved sequence block 2 in human mitochondrial DNA acts as a rheostat for RNA polymerase POLRMT activity.
Nucleic Acids Res
; 44(16): 7817-29, 2016 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27436287
10.
Structural insights into DNA sequence recognition by Type ISP restriction-modification enzymes.
Nucleic Acids Res
; 44(9): 4396-408, 2016 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26975655
11.
Translocation-coupled DNA cleavage by the Type ISP restriction-modification enzymes.
Nat Chem Biol
; 11(11): 870-7, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26389736
12.
Re-evaluating the kinetics of ATP hydrolysis during initiation of DNA sliding by Type III restriction enzymes.
Nucleic Acids Res
; 43(22): 10870-81, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26538601
13.
Mapping DNA cleavage by the Type ISP restriction-modification enzymes following long-range communication between DNA sites in different orientations.
Nucleic Acids Res
; 43(21): 10430-43, 2015 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26507855
14.
Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes.
Proc Natl Acad Sci U S A
; 111(27): 9798-803, 2014 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24912165
15.
ClpXP protease targets long-lived DNA translocation states of a helicase-like motor to cause restriction alleviation.
Nucleic Acids Res
; 42(19): 12082-91, 2014 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25260590
16.
Characterization of the Type III restriction endonuclease PstII from Providencia stuartii.
Nucleic Acids Res
; 47(21): 11477-11479, 2019 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31624830
17.
DNA cleavage by CgII and NgoAVII requires interaction between N- and R-proteins and extensive nucleotide hydrolysis.
Nucleic Acids Res
; 42(22): 13887-96, 2014 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25429977
18.
Type III restriction endonucleases are heterotrimeric: comprising one helicase-nuclease subunit and a dimeric methyltransferase that binds only one specific DNA.
Nucleic Acids Res
; 42(8): 5139-50, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24510100
19.
DNA cleavage by Type ISP Restriction-Modification enzymes is initially targeted to the 3'-5' strand.
Nucleic Acids Res
; 41(2): 1081-90, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23221632
20.
The Type ISP Restriction-Modification enzymes LlaBIII and LlaGI use a translocation-collision mechanism to cleave non-specific DNA distant from their recognition sites.
Nucleic Acids Res
; 41(2): 1071-80, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23222132