Detalhe da pesquisa
1.
Therapeutic validation of MMR-associated genetic modifiers in a human ex vivo model of Huntington disease.
Am J Hum Genet
; 111(6): 1165-1183, 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38749429
2.
The human motor cortex microcircuit: insights for neurodegenerative disease.
Nat Rev Neurosci
; 21(8): 401-415, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32555340
3.
The Huntington's Disease Gene Discovery.
Mov Disord
; 39(2): 227-234, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38179605
4.
Genetic topography and cortical cell loss in Huntington's disease link development and neurodegeneration.
Brain
; 146(11): 4532-4546, 2023 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37587097
5.
Opportunity cost determines free-operant action initiation latency and predicts apathy.
Psychol Med
; 53(5): 1850-1859, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37310334
6.
Imbalanced basal ganglia connectivity is associated with motor deficits and apathy in Huntington's disease.
Brain
; 145(3): 991-1000, 2022 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34633421
7.
Neurofilament light-associated connectivity in young-adult Huntington's disease is related to neuronal genes.
Brain
; 145(11): 3953-3967, 2022 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35758263
8.
Concern about Tominersen in Patients with Huntington's Disease. Reply.
N Engl J Med
; 390(11): 1059, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38478006
9.
Targeting Huntingtin Expression in Patients with Huntington's Disease.
N Engl J Med
; 380(24): 2307-2316, 2019 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31059641
10.
"On Chorea": 150 Years of the Beginning of Hope.
Mov Disord
; 37(11): 2194-2196, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35686970
11.
An MDS Evidence-Based Review on Treatments for Huntington's Disease.
Mov Disord
; 37(1): 25-35, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34842303
12.
Altered nuclear architecture in blood cells from Huntington's disease patients.
Neurol Sci
; 43(1): 379-385, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33974169
13.
FAN1 modifies Huntington's disease progression by stabilizing the expanded HTT CAG repeat.
Hum Mol Genet
; 28(4): 650-661, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30358836
14.
Tominersen in Adults with Manifest Huntington's Disease.
N Engl J Med
; 389(23): 2203-2205, 2023 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38055260
15.
Relating quantitative 7T MRI across cortical depths to cytoarchitectonics, gene expression and connectomics.
Hum Brain Mapp
; 42(15): 4996-5009, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34272784
16.
Human Huntington's disease pluripotent stem cell-derived microglia develop normally but are abnormally hyper-reactive and release elevated levels of reactive oxygen species.
J Neuroinflammation
; 18(1): 94, 2021 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33874957
17.
Robust Markers and Sample Sizes for Multicenter Trials of Huntington Disease.
Ann Neurol
; 87(5): 751-762, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32105364
18.
Reply to 'Topographical layer imaging as a tool to track neurodegenerative disease spread in M1'.
Nat Rev Neurosci
; 22(1): 69, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33154582
19.
Fronto-striatal circuits for cognitive flexibility in far from onset Huntington's disease: evidence from the Young Adult Study.
J Neurol Neurosurg Psychiatry
; 92(2): 143-149, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33130575
20.
Tracking Huntington's Disease Progression Using Motor, Functional, Cognitive, and Imaging Markers.
Mov Disord
; 36(10): 2282-2292, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34014005