[A patient who sufferred pulmonary tuberculosis with syndrome of inappropriate secretion of antidiuretic hormone, after radiotherapy for pulmonary adenocarcinoma].

A 62-year-old man presented in June 2006 with right thoracic pain, cough, and weight loss, which had persisted for 3 months. Chest X-ray showed a mass-like shadow in the right pulmonary apex, suggesting a stage IIIb adenocarcinoma which was confirmed by biopsy. We gave a total radiation dose of 60 Gy, after this which general malaise and weakness were noted. The results of endocrinological examinations suggested syndrome of inappropriate antidiuretic hormone secretion (SIADH). Thoracic CT showed ground-glass opacity (GGO) in both lungs, and we could not rule out pulmonary tuberculosis. A sputum was positive for acid-fast stain and PCR-Tb, suggesting that SIADH was associated with pulmonary tuberculosis. Water restriction, i.v. physiological saline, and antituberculosis therapy relieved hyponatremia and the symptoms.

[A case of adult idiopathic chylothorax with transudative ascites].

A 70-year-old woman presented at a local clinic because of shortness of breath. Since she was found to have pleural effusion, she was referred to our hospital for further evaluation. She had no history of trauma or surgery. Pleural effusion examination revealed a milky-white, chylous, odorless fluid with increased triglycerides. Further evaluation led to a diagnosis of idiopathic chylothorax. Althought she was found to have transudative ascites, abdominal ultrasonography and computed tomography revealed no significant findings including cirrhosis of the liver. As a result of intravenous hyperalimentation with fasting, the chylous pleural fluid became serous and decreased. Ascites disappeared simultaneously, suggesting a possible relationship between the chylothorax and transudative ascites.