Detalhe da pesquisa
1.
Rcn1, the fission yeast homolog of human DSCR1, regulates arsenite tolerance independently from calcineurin.
Genes Cells
; 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38715219
2.
ACAGT-007a, an anti-cancer compound that modulates ERK MAPK signaling, induces nuclear enrichment of phosphorylated ERK in T3M4 pancreatic cancer cells.
Genes Cells
; 28(6): 457-465, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-36945130
3.
Sequestration of the PKC ortholog Pck2 in stress granules as a feedback mechanism of MAPK signaling in fission yeast.
J Cell Sci
; 134(2)2021 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33277379
4.
Fission Yeast PUF Proteins Puf3 and Puf4 Are Novel Regulators of PI4P5K Signaling.
Biol Pharm Bull
; 46(2): 163-169, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36724944
5.
Down-regulation of dual-specificity phosphatase 6, a negative regulator of oncogenic ERK signaling, by ACA-28 induces apoptosis in NIH/3T3 cells overexpressing HER2/ErbB2.
Genes Cells
; 26(2): 109-116, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33249692
6.
Chemical genetic analysis of FTY720- and Ca2+ -sensitive mutants reveals a functional connection between FTY720 and membrane trafficking.
Genes Cells
; 25(9): 637-645, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32682352
7.
Discovery of new benzhydrol biscarbonate esters as potent and selective apoptosis inducers of human melanomas bearing the activated ERK pathway: SAR studies on an ERK MAPK signaling modulator, ACA-28.
Bioorg Chem
; 103: 104137, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32763519
8.
Distinct modes of stress granule assembly mediated by the KH-type RNA-binding protein Rnc1.
Genes Cells
; 23(9): 778-785, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-30014536
9.
Restricted distribution of mrg-1 mRNA in C. elegans primordial germ cells through germ granule-independent regulation.
Genes Cells
; 20(11): 932-42, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26537333
10.
Broad chromosomal domains of histone modification patterns in C. elegans.
Genome Res
; 21(2): 227-36, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21177964
11.
ACA-28, an ERK MAPK Signaling Modulator, Exerts Anticancer Activity through ROS Induction in Melanoma and Pancreatic Cancer Cells.
Oxid Med Cell Longev
; 2024: 7683793, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38500550
12.
The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny.
PLoS Genet
; 6(9): e1001091, 2010 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20824077
13.
Atg1, a key regulator of autophagy, functions to promote MAPK activation and cell death upon calcium overload in fission yeast.
Microb Cell
; 10(6): 133-140, 2023 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37275474
14.
ACA-28, an anticancer compound, induces Pap1 nuclear accumulation via ROS-dependent and -independent mechanisms in fission yeast.
MicroPubl Biol
; 20232023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37720683
15.
Autophagy-related genes genetically interact with Pmk1 MAPK signaling in fission yeast.
MicroPubl Biol
; 20222022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35996690
16.
ACAGT-007a, an ERK MAPK Signaling Modulator, in Combination with AKT Signaling Inhibition Induces Apoptosis in KRAS Mutant Pancreatic Cancer T3M4 and MIA-Pa-Ca-2 Cells.
Cells
; 11(4)2022 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35203351
17.
Ellagic Acid Combined with Tacrolimus Showed Synergistic Cell Growth Inhibition in Fission Yeast.
Biocontrol Sci
; 27(1): 31-39, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35314558
18.
ERK: A Double-Edged Sword in Cancer. ERK-Dependent Apoptosis as a Potential Therapeutic Strategy for Cancer.
Cells
; 10(10)2021 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34685488
19.
Distinct spatiotemporal distribution of Hsp90 under high-heat and mild-heat stress conditions in fission yeast.
MicroPubl Biol
; 20212021 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34036246
20.
More than Just an Immunosuppressant: The Emerging Role of FTY720 as a Novel Inducer of ROS and Apoptosis.
Oxid Med Cell Longev
; 2018: 4397159, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29785244