Detalhe da pesquisa
1.
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement.
Cell
; 172(1-2): 305-317.e10, 2018 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29328918
2.
Extracellular ATP activates hyaluronan synthase 2 (HAS2) in epidermal keratinocytes via P2Y2, Ca2+ signaling, and MAPK pathways.
Biochem J
; 475(10): 1755-1772, 2018 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29626161
3.
Single-Molecule Unbinding Forces between the Polysaccharide Hyaluronan and Its Binding Proteins.
Biophys J
; 114(12): 2910-2922, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29925027
4.
Human Keratinocytes Respond to Extracellular UTP by Induction of Hyaluronan Synthase 2 Expression and Increased Hyaluronan Synthesis.
J Biol Chem
; 292(12): 4861-4872, 2017 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28188289
5.
Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3.
J Biol Chem
; 290(18): 11479-90, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25795779
6.
Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis.
Glycobiology
; 26(7): 710-22, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26887390
7.
Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes.
J Biol Chem
; 289(26): 18569-81, 2014 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24847057
8.
Rab10-mediated endocytosis of the hyaluronan synthase HAS3 regulates hyaluronan synthesis and cell adhesion to collagen.
J Biol Chem
; 289(12): 8375-89, 2014 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24509846
9.
Decreased hyaluronidase 1 expression is associated with early disease recurrence in human endometrial cancer.
Gynecol Oncol
; 137(1): 152-9, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25584766
10.
Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GlcNAc concentration than HAS2 and HAS3.
J Biol Chem
; 288(8): 5973-83, 2013 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23303191
11.
Hyaluronan production enhances shedding of plasma membrane-derived microvesicles.
Exp Cell Res
; 319(13): 2006-2018, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23732660
12.
Isothiocyanate analogs targeting CD44 receptor as an effective strategy against colon cancer.
Med Chem Res
; 23(8): 3836-3851, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25013352
13.
Hyaluronan in cytosol--microinjection-based probing of its existence and suggested functions.
Glycobiology
; 23(2): 222-31, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23086746
14.
Mannose reduces hyaluronan and leukocytes in wound granulation tissue and inhibits migration and hyaluronan-dependent monocyte binding.
Wound Repair Regen
; 21(2): 247-55, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23464634
15.
Cellular content of UDP-N-acetylhexosamines controls hyaluronan synthase 2 expression and correlates with O-linked N-acetylglucosamine modification of transcription factors YY1 and SP1.
J Biol Chem
; 286(38): 33632-40, 2011 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21795679
16.
HAS3-induced accumulation of hyaluronan in 3D MDCK cultures results in mitotic spindle misorientation and disturbed organization of epithelium.
Histochem Cell Biol
; 137(2): 153-64, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22159845
17.
Synthesis and fragmentation of hyaluronan in renal ischaemia.
Nephrol Dial Transplant
; 27(10): 3771-81, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22529164
18.
Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal squamous carcinoma cells.
J Biol Chem
; 285(30): 23276-84, 2010 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20463012
19.
Methyl-beta-cyclodextrin suppresses hyaluronan synthesis by down-regulation of hyaluronan synthase 2 through inhibition of Akt.
J Biol Chem
; 285(30): 22901-10, 2010 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20501660
20.
Regulation of the hyaluronan synthase 2 gene by convergence in cyclic AMP response element-binding protein and retinoid acid receptor signaling.
J Biol Chem
; 284(27): 18270-81, 2009 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19416972