Detalhe da pesquisa
1.
A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency.
Proc Natl Acad Sci U S A
; 117(40): 24802-24812, 2020 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32958664
2.
Sunitinib inhibits RNase L by destabilizing its active dimer conformation.
Biochem J
; 477(17): 3387-3399, 2020 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32830849
3.
Immunotherapy based on bispecific T-cell engager with hIgG1 Fc sequence as a new therapeutic strategy in multiple myeloma.
Cancer Sci
; 106(5): 512-21, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25664501
4.
Identification of Small Molecule Inhibitors of RNase L by Fragment-Based Drug Discovery.
J Med Chem
; 65(2): 1445-1457, 2022 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34841869
5.
The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery.
Nat Commun
; 12(1): 488, 2021 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33473130
6.
Repurposing clinically approved drugs for COVID-19 treatment targeting SARS-CoV-2 papain-like protease.
Int J Biol Macromol
; 188: 137-146, 2021 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34364941
7.
Novel CD7-specific nanobody-based immunotoxins potently enhanced apoptosis of CD7-positive malignant cells.
Oncotarget
; 7(23): 34070-83, 2016 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27083001
8.
Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling.
Cancer Cell
; 29(5): 639-652, 2016 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27132469
9.
HMGB1 Promotes Mitochondrial Dysfunction-Triggered Striatal Neurodegeneration via Autophagy and Apoptosis Activation.
PLoS One
; 10(11): e0142901, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26565401