Detalhe da pesquisa
1.
siRNA screen identifies QPCT as a druggable target for Huntington's disease.
Nat Chem Biol
; 11(5): 347-354, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25848931
2.
Noncanonical-NF-κB activation and DDX3 inhibition reduces the HIV-1 reservoir by elimination of latently infected cells ex-vivo.
Microbiol Spectr
; 12(1): e0318023, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38051053
3.
The FHP01 DDX3X Helicase Inhibitor Exerts Potent Anti-Tumor Activity In Vivo in Breast Cancer Pre-Clinical Models.
Cancers (Basel)
; 13(19)2021 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34638314
4.
Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.
J Neurosci
; 25(43): 9932-9, 2005 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-16251441
5.
A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours.
Nat Commun
; 6: 7227, 2015 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26085373
6.
Reference genes selection for transcriptional profiling in blood of HD patients and R6/2 mice.
J Huntingtons Dis
; 2(2): 185-200, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-25063515
7.
Brain-derived neurotrophic factor in patients with Huntington's disease.
PLoS One
; 6(8): e22966, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21857974
8.
Therapeutic targets for Alzheimer's disease.
Expert Opin Ther Targets
; 13(5): 551-67, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19368497
9.
Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease.
Neurobiol Dis
; 28(1): 133-42, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17702587
10.
Severe deficiency of the fatty acid amide hydrolase (FAAH) activity segregates with the Huntington's disease mutation in peripheral lymphocytes.
Neurobiol Dis
; 27(1): 108-16, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17553686
11.
Early and transient alteration of adenosine A2A receptor signaling in a mouse model of Huntington disease.
Neurobiol Dis
; 23(1): 44-53, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16651003
12.
Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery.
Pharmacol Res
; 52(2): 133-9, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15967378