Detalhe da pesquisa
1.
Enhanced amyloid-ß generation by γ-secretase complex in DRM microdomains with reduced cholesterol levels.
Hum Mol Genet
; 29(3): 382-393, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31841137
2.
Suppression of amyloid-ß secretion from neurons by cis-9, trans-11-octadecadienoic acid, an isomer of conjugated linoleic acid.
J Neurochem
; 159(3): 603-617, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34379812
3.
RIMB-1/RIM-Binding Protein and UNC-10/RIM Redundantly Regulate Presynaptic Localization of the Voltage-Gated Calcium Channel in Caenorhabditis elegans.
J Neurosci
; 39(44): 8617-8631, 2019 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31530643
4.
SYD-1C, UNC-40 (DCC) and SAX-3 (Robo) function interdependently to promote axon guidance by regulating the MIG-2 GTPase.
PLoS Genet
; 11(4): e1005185, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25876065
5.
Cytoplasmic fragment of Alcadein α generated by regulated intramembrane proteolysis enhances amyloid ß-protein precursor (APP) transport into the late secretory pathway and facilitates APP cleavage.
J Biol Chem
; 290(2): 987-95, 2015 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25406318
6.
Axonal transport of Frizzled5 by Alcadein α-containing vesicles is associated with kinesin-1.
Mol Biol Cell
; 34(11): ar110, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37585286
7.
Accumulation of amyloid-ß in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging.
Neurobiol Aging
; 123: 63-74, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36638682
8.
Brain p3-Alcß peptide restores neuronal viability impaired by Alzheimer's amyloid ß-peptide.
EMBO Mol Med
; 15(5): e17052, 2023 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36994913
9.
The Liprin homology domain is essential for the homomeric interaction of SYD-2/Liprin-α protein in presynaptic assembly.
J Neurosci
; 31(45): 16261-8, 2011 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22072677
10.
SYD-2 Liprin-alpha organizes presynaptic active zone formation through ELKS.
Nat Neurosci
; 9(12): 1479-87, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17115037
11.
Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP.
J Neurochem
; 109(2): 465-75, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19222704
12.
The cytoplasmic region of the amyloid ß-protein precursor (APP) is necessary and sufficient for the enhanced fast velocity of APP transport by kinesin-1.
FEBS Lett
; 592(16): 2716-2724, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30055048
13.
Phosphorylation of KLC1 modifies interaction with JIP1 and abolishes the enhanced fast velocity of APP transport by kinesin-1.
Mol Biol Cell
; 28(26): 3857-3869, 2017 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29093025
14.
Effects and mechanisms of prolongevity induced by Lactobacillus gasseri SBT2055 in Caenorhabditis elegans.
Aging Cell
; 15(2): 227-36, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26710940
15.
Suppression of the caspase cleavage of beta-amyloid precursor protein by its cytoplasmic phosphorylation.
FEBS Lett
; 567(2-3): 248-52, 2004 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15178331
16.
Increased levels of plasma p3-alcα35, a major fragment of Alcadeinα by γ-secretase cleavage, in Alzheimer's disease.
J Alzheimers Dis
; 39(4): 861-70, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24305499
17.
Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport.
Mol Biol Cell
; 25(22): 3569-80, 2014 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25165140
18.
Mechanism of intramembrane cleavage of alcadeins by γ-secretase.
PLoS One
; 8(4): e62431, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23658629
19.
Liprin-α/SYD-2 determines the size of dense projections in presynaptic active zones in C. elegans.
J Cell Biol
; 203(5): 849-63, 2013 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24322429
20.
Intracellular trafficking of the amyloid ß-protein precursor (APP) regulated by novel function of X11-like.
PLoS One
; 6(7): e22108, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21818298