Detalhe da pesquisa
1.
Benznidazole treatment leads to DNA damage in Trypanosoma cruzi and the persistence of rare widely dispersed non-replicative amastigotes in mice.
PLoS Pathog
; 19(11): e1011627, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37956215
2.
Local association of Trypanosoma cruzi chronic infection foci and enteric neuropathic lesions at the tissue micro-domain scale.
PLoS Pathog
; 17(8): e1009864, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34424944
3.
Incomplete Recruitment of Protective T Cells Is Associated with Trypanosoma cruzi Persistence in the Mouse Colon.
Infect Immun
; 90(2): e0038221, 2022 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34780279
4.
Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles.
J Enzyme Inhib Med Chem
; 36(1): 1952-1967, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34455887
5.
Shaving Is an Epiphenomenon of Type I and II Anti-CD20-Mediated Phagocytosis, whereas Antigenic Modulation Limits Type I Monoclonal Antibody Efficacy.
J Immunol
; 201(4): 1211-1221, 2018 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29997125
6.
Challenges in Chagas Disease Drug Development.
Molecules
; 25(12)2020 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32560454
7.
Synthesis of diphenoxyadamantane alkylamines with pharmacological interest.
Bioorg Med Chem Lett
; 29(11): 1278-1281, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30981579
8.
Assessing the Effectiveness of Curative Benznidazole Treatment in Preventing Chronic Cardiac Pathology in Experimental Models of Chagas Disease.
Antimicrob Agents Chemother
; 62(10)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30082291
9.
Synthesis, anti-bacterial and anti-protozoal activities of amidinobenzimidazole derivatives and their interactions with DNA and RNA.
J Enzyme Inhib Med Chem
; 33(1): 1323-1334, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30165753
10.
Tetrasubstituted Imidazolium Salts as Potent Antiparasitic Agents against African and American Trypanosomiases.
Molecules
; 23(1)2018 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29337878
11.
Host and parasite genetics shape a link between Trypanosoma cruzi infection dynamics and chronic cardiomyopathy.
Cell Microbiol
; 18(10): 1429-43, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26918803
12.
Biological factors that impinge on Chagas disease drug development.
Parasitology
; 144(14): 1871-1880, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28831944
13.
TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei.
Nucleic Acids Res
; 43(Database issue): D637-44, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25300491
14.
Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.
Bioorg Med Chem
; 24(21): 5162-5171, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27591008
15.
Limited Ability of Posaconazole To Cure both Acute and Chronic Trypanosoma cruzi Infections Revealed by Highly Sensitive In Vivo Imaging.
Antimicrob Agents Chemother
; 59(8): 4653-61, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26014936
16.
Bioluminescence imaging of chronic Trypanosoma cruzi infections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection.
Cell Microbiol
; 16(9): 1285-300, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24712539
17.
Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal-antiplasmodial activity.
Bioorg Med Chem
; 23(16): 5156-67, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25678015
18.
Evidence that transport of iron from the lysosome to the cytosol in African trypanosomes is mediated by a mucolipin orthologue.
Mol Microbiol
; 89(3): 420-32, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23750752
19.
Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines.
Bioorg Med Chem Lett
; 24(23): 5435-8, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25454267
20.
Pathogen imaging applications.
Methods
; 127: 1-2, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28867066