Detalhe da pesquisa
1.
Telomerase reverse transcriptase delays aging in cancer-resistant mice.
Cell
; 135(4): 609-22, 2008 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19013273
2.
A synthetic mRNA cell reprogramming method using CYCLIN D1 promotes DNA repair, generating improved genetically stable human induced pluripotent stem cells.
Stem Cells
; 39(7): 866-881, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33621399
3.
AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer.
PLoS Genet
; 14(8): e1007562, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30114189
4.
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice.
Genes Dev
; 23(17): 2060-75, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19679647
5.
Questions and answers in the management of children with medulloblastoma over the time. How did we get here? A systematic review.
Front Oncol
; 13: 1229853, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37456257
6.
Ten Reasons Why People With Down Syndrome are Protected From the Development of Most Solid Tumors -A Review.
Front Genet
; 12: 749480, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34804119
7.
Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres.
Elife
; 72018 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29378675
8.
Generation of mice with longer and better preserved telomeres in the absence of genetic manipulations.
Nat Commun
; 7: 11739, 2016 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27252083
9.
ATRX driver mutation in a composite malignant pheochromocytoma.
Cancer Genet
; 209(6): 272-7, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27209355
10.
Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction.
Nat Commun
; 5: 5863, 2014 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25519492
11.
Localization-dependent and -independent roles of SLX4 in regulating telomeres.
Cell Rep
; 4(5): 853-60, 2013 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23994477
12.
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer.
EMBO Mol Med
; 4(8): 691-704, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22585399
13.
The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence.
Aging Cell
; 10(4): 604-21, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21426483
14.
ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase.
J Cell Biol
; 188(5): 639-52, 2010 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20212315
15.
TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice.
Dev Cell
; 18(5): 775-89, 2010 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20493811
16.
Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites.
Nat Cell Biol
; 12(8): 768-80, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20622869
17.
Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells.
Cell Stem Cell
; 4(2): 141-54, 2009 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19200803
18.
The longest telomeres: a general signature of adult stem cell compartments.
Genes Dev
; 22(5): 654-67, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18283121
19.
Porphyrin derivatives for telomere binding and telomerase inhibition.
Chembiochem
; 6(1): 123-32, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15551357
20.
Zidovudine induces S-phase arrest and cell cycle gene expression changes in human cells.
Mutagenesis
; 20(2): 139-46, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15784690