Dental alterations on panoramic radiographs of patients with osteogenesis imperfecta in relation to clinical diagnosis, severity, and bisphosphonate regimen aspects: a STROBE-compliant case-control study.

OBJECTIVE: This study aimed to assess the prevalence of dental findings on panoramic radiographs (PRs) of patients with osteogenesis imperfecta (OI) and correlate these results with epidemiologic and medical data. STUDY DESIGN: A case-control study was conducted with 24 patients with OI and 48 sex- and age-matched controls. Demographic, clinical, and bisphosphonate regimen-related data were recorded. The outcome variables were the presence or absence of dental alterations in PRs. Mann-Whitney U test, Pearson's χ2 test, and multinomial logistic regression analysis (95% confidence interval) were used (significance level of 5%). RESULTS: OI type 4 demonstrated a high prevalence (62.5%), followed by type 1 (37.5%). With regard to prevalence associated with severity, the moderate form was the most prevalent (P = .028). The mean time of intravenous pamidronate regimen was 6.6 ± 4.4 years. Dentinogenesis imperfecta was observed in 75% of patients with OI, and this group showed a high prevalence of dental abnormalities in comparison with controls (P < .05). Bisphosphonate therapy was associated with ectopic teeth (P = .007) and tooth impaction (P = .033). Pulp obliteration was significant with bisphosphonate treatment over a period of 7 years (P = .026). CONCLUSIONS: This study found a significant prevalence of dental alterations in patients with OI, and certain alterations were associated with bisphosphonate therapy, indicating its influence on the dentin-related physiopathology.

Fatores associados à subestimação materna do peso da criança: um estudo de base populacional / Factors associated with maternal underestimation of child's weight: a population-based study

Objetivo Investigar os fatores associados à subestimação materna do peso de crianças menores de cinco anos de Goiânia, Goiás. Métodos Estudo transversal, de base populacional, domiciliar, com 673 crianças menores de cinco anos de idade. A percepção materna do peso da criança foi obtida pela pergunta: "Atualmente, o que a senhora (mãe) acha do peso do seu filho?", e o estado nutricional da criança foi avaliado pelo índice de massa corporal por idade. Regressão múltipla de Poisson foi realizada a um nível de significância de 5%. Para a análise de concordância, foi utilizado o teste Kappa. Resultados Das crianças estudadas, 1,6% estavam magras, 87,7% eutróficas e 10,7% com excesso de peso. A maioria das mães (66,0%) identificou corretamente o peso de seus filhos; 5,2% superestimaram, e 28,8% subestimaram. Mães de crianças com excesso de peso, idade superior a 24 meses, apresentaram maior prevalência de subestimação, enquanto as mães com excesso de peso e maior escolaridade apresentaram menor subestimação do peso das crianças. A concordância entre a opinião materna sobre o peso da criança e o real estado nutricional da criança foi de 0,12 (p<0,001). CONCLUSÃO Existe uma distorção na percepção materna do peso de crianças menores de cinco anos. A subestimação materna do peso da criança apresentou associação direta com idade e estado nutricional da criança e associação inversa com escolaridade e estado nutricional materno. Sugere-se atenção no atendimento a essas mães com o objetivo de evitar o ganho de peso excessivo nessa idade e prejuízos na saúde da criança. .

Objective To investigate the factors associated with maternal underestimation of weight status of children under five years in Goiânia, Goiás, Brazil. Methods A population-based cross-sectional study involving 673 children under five years of age was carried out. Maternal perception of child's weight was assessed by the question: "What do you think about your child's current weight?". The child's nutritional status was determined in terms of body mass index-for age. Poisson regression was used at 5% significance level. Concordance analysis was performed using the Kappa test. Results Among the children studied, 1.6 % were lean, 87.7% eutrophic, and 10.7% overweight. Most mothers (66.0%) correctly classified the weight of their children, 5.2% overestimated it, and 28.8% underestimated it. Mothers of overweight children and those whose children were older than 24 months had a higher prevalence of underestimation of weight, whereas the overweight mothers and those with higher education level had a lower prevalence of underestimation of weight of their children. The correlation between maternal perception of the chil's weight and the actual child's nutritional status was 0.12 (p<0.001). Conclusion Maternal misperception of weight of children under five years was observed. Maternal underestimation of their child's weight was directly associated with age and nutritional status of the child, and it was inversely associated with maternal education level and nutritional status. More attention should be paid to these mothers in order to prevent excessive weight gain at this age and further harm to children's health. .