Detalhe da pesquisa
1.
Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development.
Cell
; 151(6): 1200-13, 2012 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23217707
2.
Structural and functional analysis of the DOT1L-AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis.
Genes Dev
; 32(5-6): 341-346, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29563185
3.
Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev
; 29(22): 2343-8, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26543161
4.
Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Nat Chem Biol
; 14(5): 466-473, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29632410
5.
First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.
Proc Natl Acad Sci U S A
; 114(38): 10125-10130, 2017 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28864533
6.
Chromokinesins NOD and KID Use Distinct ATPase Mechanisms and Microtubule Interactions To Perform a Similar Function.
Biochemistry
; 58(18): 2326-2338, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30973712
7.
The tuberous sclerosis complex subunit TBC1D7 is stabilized by Akt phosphorylation-mediated 14-3-3 binding.
J Biol Chem
; 293(42): 16142-16159, 2018 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30143532
8.
Peptide recognition by heterochromatin protein 1 (HP1) chromoshadow domains revisited: Plasticity in the pseudosymmetric histone binding site of human HP1.
J Biol Chem
; 292(14): 5655-5664, 2017 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28223359
9.
A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1.
Nat Chem Biol
; 12(3): 180-7, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26807715
10.
Family-wide Characterization of Histone Binding Abilities of Human CW Domain-containing Proteins.
J Biol Chem
; 291(17): 9000-13, 2016 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26933034
11.
Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP.
Biochem J
; 473(2): 179-87, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26527736
12.
Crystal structure of DPF3b in complex with an acetylated histone peptide.
J Struct Biol
; 195(3): 365-372, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27402533
13.
Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain.
Nat Chem Biol
; 10(11): 927-9, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25242552
14.
Addendum: A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1.
Nat Chem Biol
; 15(8): 846, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30842648
15.
New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms.
Bioorg Med Chem Lett
; 26(18): 4518-4522, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27485386
16.
Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.
J Biol Chem
; 289(25): 17299-311, 2014 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24778178
17.
Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
EMBO J
; 30(14): 2829-42, 2011 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21685874
18.
Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain.
Nat Chem Biol
; 9(3): 184-91, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23292653
19.
Structural characterization of human cholesterol 7α-hydroxylase.
J Lipid Res
; 55(9): 1925-32, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24927729
20.
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
Nat Chem Biol
; 8(10): 839-47, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22922757