Detalhe da pesquisa
1.
BET bromodomain inhibitors regulate keratinocyte plasticity.
Nat Chem Biol
; 17(3): 280-290, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33462494
2.
Constitutive androstane receptor 1 is constitutively bound to chromatin and 'primed' for transactivation in hepatocytes.
Mol Pharmacol
; 95(1): 97-105, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30361333
3.
Computational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion.
Nucleic Acids Res
; 42(7): 4180-95, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24464994
4.
Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver.
Nucleic Acids Res
; 41(11): 5639-54, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23598998
5.
Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques.
Nucleic Acids Res
; 41(22): e206, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24214958
6.
Target genes of Topoisomerase IIß regulate neuronal survival and are defined by their chromatin state.
Proc Natl Acad Sci U S A
; 109(16): E934-43, 2012 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22474351
7.
Ha-ras and ß-catenin oncoproteins orchestrate metabolic programs in mouse liver tumors.
Int J Cancer
; 135(7): 1574-85, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24535843
8.
Wdr5 is essential for fetal erythropoiesis and hematopoiesis.
Exp Hematol Oncol
; 12(1): 39, 2023 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37061728
9.
Unaltered hepatic wound healing response in male rats with ancestral liver injury.
Nat Commun
; 14(1): 6353, 2023 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37816736
10.
Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies.
J Med Chem
; 65(7): 5317-5333, 2022 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35352560
11.
Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2.
PLoS Genet
; 4(9): e1000170, 2008 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18773085
12.
Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion.
Life Sci Alliance
; 2(5)2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31615920
13.
IRF2 is a master regulator of human keratinocyte stem cell fate.
Nat Commun
; 10(1): 4676, 2019 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31611556
14.
[The many faces of constitutive heterochromatin]. / L'hétérochromatine constitutive dans tous ses états.
Med Sci (Paris)
; 24(8-9): 720-4, 2008.
Artigo
em Francês
| MEDLINE | ID: mdl-18789218
15.
Chromatin dynamics underlying latent responses to xenobiotics.
Toxicol Res (Camb)
; 7(4): 606-617, 2018 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30090610
16.
Xenobiotic CAR Activators Induce Dlk1-Dio3 Locus Noncoding RNA Expression in Mouse Liver.
Toxicol Sci
; 158(2): 367-378, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28541575
17.
Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1.
ACS Med Chem Lett
; 8(2): 151-156, 2017 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28197303
18.
Evaluation of 5-methylcytosine and 5-hydroxymethylcytosine as potential biomarkers for characterisation of chemical allergens.
Toxicology
; 340: 17-26, 2016 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26732893
19.
Reciprocal changes in DNA methylation and hydroxymethylation and a broad repressive epigenetic switch characterize FMR1 transcriptional silencing in fragile X syndrome.
Clin Epigenetics
; 8: 15, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26855684
20.
Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer.
Cancer Res
; 76(10): 3097-108, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27197233