Detalhe da pesquisa
1.
A Global Map of G Protein Signaling Regulation by RGS Proteins.
Cell
; 183(2): 503-521.e19, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33007266
2.
A Receptor on Acid.
Cell
; 168(3): 339-341, 2017 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28129534
3.
Hitchhiking on the heptahelical highway: structure and function of 7TM receptor complexes.
Nat Rev Mol Cell Biol
; 17(7): 439-50, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27093944
4.
Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature
; 595(7868): 600-605, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34262173
5.
Residue-wise local quality estimation for protein models from cryo-EM maps.
Nat Methods
; 19(9): 1116-1125, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35953671
6.
Atypical Chemokine Receptor 3 "Senses" CXC Chemokine Receptor 4 Activation Through GPCR Kinase Phosphorylation.
Mol Pharmacol
; 104(4): 174-186, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37474305
7.
G protein-coupled receptor interactions with arrestins and GPCR kinases: The unresolved issue of signal bias.
J Biol Chem
; 298(9): 102279, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35863432
8.
Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1.
J Biol Chem
; 298(8): 102209, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35779635
9.
Perturbation of the interactions of calmodulin with GRK5 using a natural product chemical probe.
Proc Natl Acad Sci U S A
; 116(32): 15895-15900, 2019 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31337679
10.
Inhibition of lysosomal phospholipase A2 predicts drug-induced phospholipidosis.
J Lipid Res
; 62: 100089, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34087196
11.
The first DEP domain of the RhoGEF P-Rex1 autoinhibits activity and contributes to membrane binding.
J Biol Chem
; 295(36): 12635-12647, 2020 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32661198
12.
Discovery of Small Molecules That Target the Phosphatidylinositol (3,4,5) Trisphosphate (PIP3)-Dependent Rac Exchanger 1 (P-Rex1) PIP3-Binding Site and Inhibit P-Rex1-Dependent Functions in Neutrophils.
Mol Pharmacol
; 97(3): 226-236, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31900312
13.
A New Paroxetine-Based GRK2 Inhibitor Reduces Internalization of the µ-Opioid Receptor.
Mol Pharmacol
; 97(6): 392-401, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32234810
14.
Phospholipid Component Defines Pharmacokinetic and Pharmacodynamic Properties of Synthetic High-Density Lipoproteins.
J Pharmacol Exp Ther
; 372(2): 193-204, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31776208
15.
Characterization of a hyperphosphorylated variant of G protein-coupled receptor kinase 5 expressed in E. coli.
Protein Expr Purif
; 168: 105547, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31786308
16.
Structural Basis of Lysosomal Phospholipase A2 Inhibition by Zn2.
Biochemistry
; 58(13): 1709-1717, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30830753
17.
Tracking the Cartoon mouse phenotype: Hemopexin domain-dependent regulation of MT1-MMP pericellular collagenolytic activity.
J Biol Chem
; 293(21): 8113-8127, 2018 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29643184
18.
Synthesis of deuterium-labelled amlexanox and its metabolic stability against mouse, rat, and human microsomes.
J Labelled Comp Radiopharm
; 62(5): 202-208, 2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30828860
19.
Determinants of pH profile and acyl chain selectivity in lysosomal phospholipase A2.
J Lipid Res
; 59(7): 1205-1218, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29724779
20.
Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKε and Reveal Mechanisms for Selective Inhibition.
Mol Pharmacol
; 94(4): 1210-1219, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30082428