Detalhe da pesquisa
1.
Two-long terminal repeat (LTR) DNA circles are a substrate for HIV-1 integrase.
J Biol Chem
; 294(20): 8286-8295, 2019 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30971426
2.
Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration.
Retrovirology
; 12: 24, 2015 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25808736
3.
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives.
Antimicrob Agents Chemother
; 58(10): 6101-10, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25092689
4.
Quantitative analysis of the time-course of viral DNA forms during the HIV-1 life cycle.
Retrovirology
; 10: 87, 2013 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23938039
5.
TL-532, a novel specific Toll-like receptor 3 agonist rationally designed for targeting cancers: discovery process and biological characterization.
Microb Cell
; 10(6): 117-132, 2023 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37275475
6.
A Chemically Defined TLR3 Agonist with Anticancer Activity.
Oncoimmunology
; 12(1): 2227510, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37389102
7.
Chromosomal tethering and proviral integration.
Biochim Biophys Acta
; 1799(3-4): 207-16, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-19683084
8.
Impact of Y143 HIV-1 integrase mutations on resistance to raltegravir in vitro and in vivo.
Antimicrob Agents Chemother
; 54(1): 491-501, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19901095
9.
AsiDNA Treatment Induces Cumulative Antitumor Efficacy with a Low Probability of Acquired Resistance.
Neoplasia
; 21(9): 863-871, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31362243
10.
Preclinical Studies Comparing Efficacy and Toxicity of DNA Repair Inhibitors, Olaparib, and AsiDNA, in the Treatment of Carboplatin-Resistant Tumors.
Front Oncol
; 9: 1097, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31781480
11.
High-mobility group box 1 protein induces HIV-1 expression from persistently infected cells.
AIDS
; 21(3): 283-92, 2007 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-17255735
12.
Activation of sPLA2-IIA and PGE2 production by high mobility group protein B1 in vascular smooth muscle cells sensitized by IL-1beta.
FASEB J
; 20(10): 1727-9, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16807371
13.
Micronuclei Frequency in Tumors Is a Predictive Biomarker for Genetic Instability and Sensitivity to the DNA Repair Inhibitor AsiDNA.
Cancer Res
; 77(16): 4207-4216, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28588010
14.
The DNA Repair Inhibitor Dbait Is Specific for Malignant Hematologic Cells in Blood.
Mol Cancer Ther
; 16(12): 2817-2827, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28947503
15.
Drug-Driven Synthetic Lethality: Bypassing Tumor Cell Genetics with a Combination of AsiDNA and PARP Inhibitors.
Clin Cancer Res
; 23(4): 1001-1011, 2017 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27559053
16.
Opposite transcriptional regulation of integrated vs unintegrated HIV genomes by the NF-κB pathway.
Sci Rep
; 6: 25678, 2016 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27167871
17.
Dual and Opposite Effects of hRAD51 Chemical Modulation on HIV-1 Integration.
Chem Biol
; 22(6): 712-23, 2015 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26051216
18.
Comparison Between Several Integrase-defective Lentiviral Vectors Reveals Increased Integration of an HIV Vector Bearing a D167H Mutant.
Mol Ther Nucleic Acids
; 3: e213, 2014 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25462529
19.
Impact of the Ku complex on HIV-1 expression and latency.
PLoS One
; 8(7): e69691, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23922776
20.
Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection.
J Exp Med
; 208(9): 1823-34, 2011 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-21859844