RESUMO
The dynamics of RNA and protein metabolism (as indicated by the incorporation of labeled precursors) during electrophysiological 'learning" and electrical stimulation of isolated ganglia of the snails Tritonia diomedia and Helix pomatia has been investigated. 'Learning" phenomenon manifested itself in the maintenance of synchronous discharges in the electrical activity of the neurons after cessation of the stimulus. At all the electrical stimulations, fast periodic processes of accumulation-degradation of RNA and protein were observed. Radioautographic studies indicate that these processes begin at first in the glia and then in the neurons. The pattern of incorporation of the precursor into the protein is similar to that into RNA, indicating that short-living RNA is involved into the synthesis of short-living proteins. Aurantin (a mixture of actinomycines) inhibits glial synthesis of RNA to a greater extent than neuronal one,-both at rest and electrical stimulation. On the other side, aurantin hinders or even completely blocks "learning" phenomenon. It is suggested that normal RNA metabolism is necessary for the formation of trace phenomena. No essential differences in the metabolism of RNA, protein and nucleotides were found during "learning" and stimulation.
Assuntos
Encéfalo/metabolismo , RNA/metabolismo , Caramujos/metabolismo , Animais , Encéfalo/efeitos dos fármacos , Flavonoides/farmacologia , Caracois Helix/metabolismo , Especificidade da EspécieRESUMO
An analysis of the results of the treatment of 180 donor wounds following cutting off thick or full-thickness grafts by means of a dermatome in 123 patients with post-burn deformities and contractures is presented. The healing period variants, depending on the thickness of the grafts and on the treatment method, have been found. The authors recommend to cover the donor wounds with thin grafts or with sieve grafts.
Assuntos
Transplante de Pele , Cicatrização , Adolescente , Adulto , Bandagens , Criança , Pré-Escolar , Cicatriz/cirurgia , Contratura/cirurgia , Humanos , Lactente , Pessoa de Meia-Idade , Fatores de Tempo , Transplante AutólogoAssuntos
Química Encefálica , Cerebelo/análise , Córtex Cerebral/análise , Condicionamento Clássico , RNA/análise , Animais , Comportamento Alimentar , Ratos , TempoAssuntos
Química Encefálica , Cerebelo/fisiologia , Córtex Cerebral/fisiologia , Condicionamento Clássico , Hipocampo/fisiologia , Aprendizagem , RNA/fisiologia , Animais , Núcleo Celular/análise , Núcleo Celular/fisiologia , Cerebelo/análise , Córtex Cerebral/análise , Alimentos , Hipocampo/análise , Cinética , Luz , Memória , Neurônios/análise , Neurônios/fisiologia , Ratos , Tempo de ReaçãoRESUMO
The NEMO 3 detector, which has been operating in the Fréjus underground laboratory since February 2003, is devoted to the search for neutrinoless double-beta decay (beta beta 0v). The half-lives of the two neutrino double-beta decay (beta beta 2v) have been measured for 100Mo and 82Se. After 389 effective days of data collection from February 2003 until September 2004 (phase I), no evidence for neutrinoless double-beta decay was found from approximately 7 kg of 100Mo and approximately 1 kg of 82Se. The corresponding limits are T1/2(beta beta0v) > 4.6 x 10(23) yr for 100Mo and T1/2(beta beta 0v) > 1.0 x 10(23) yr for 82Se (90% C.L.). Depending on the nuclear matrix element calculation, the limits for the effective Majorana neutrino mass are
RESUMO
Immunologic examinations of 60 patients suffering from common hard drinking and of 24 chronic alcoholics, stage I, has revealed a clear-cut difference in the levels of circulating immune complexes and theophylline-sensitive lymphocytes in these populations. These data are recommended as additional tests for the differential diagnosis of the initial forms of alcoholism.