Detalhe da pesquisa
1.
Novel quinazolin-4(3H)-one based Cyclin K degraders regulate alternative polyadenylation activity.
Biochem Biophys Res Commun
; 676: 6-12, 2023 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37480690
2.
Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice.
Angew Chem Int Ed Engl
; 60(17): 9279-9283, 2021 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33433953
3.
Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome InhibitorsâPart II.
J Med Chem
; 66(2): 1484-1508, 2023 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36630286
4.
Total syntheses of (+)-polygalolideâ a and (+)-polygalolideâ b: elucidation of the absolute stereochemistry and biogenetic implications.
Chemistry
; 18(31): 9682-90, 2012 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22760948
5.
Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors.
J Med Chem
; 65(13): 9350-9375, 2022 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35727231
6.
Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome.
J Med Chem
; 64(9): 6262-6272, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33949190
7.
Discovery of 3-Benzyl-1-( trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors.
J Med Chem
; 61(17): 7710-7728, 2018 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30067358