Detalhe da pesquisa
1.
The ketone body ß-hydroxybutyrate shifts microglial metabolism and suppresses amyloid-ß oligomer-induced inflammation in human microglia.
FASEB J
; 37(11): e23261, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37878335
2.
Nonphagocytic Activation of NOX2 Is Implicated in Progressive Nonalcoholic Steatohepatitis During Aging.
Hepatology
; 72(4): 1204-1218, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31950520
3.
Shc inhibitor idebenone ameliorates liver injury and fibrosis in dietary NASH in mice.
J Biochem Mol Toxicol
; 35(10): e22876, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34369032
4.
Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition.
Pharmacol Res
; 137: 89-103, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30290222
5.
p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria.
J Biol Chem
; 291(24): 12575-12585, 2016 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27059956
6.
Galectin-3 regulates inflammasome activation in cholestatic liver injury.
FASEB J
; 30(12): 4202-4213, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27630169
7.
Ketogenic diet and BHB rescue the fall of long-term potentiation in an Alzheimer's mouse model and stimulates synaptic plasticity pathway enzymes.
Commun Biol
; 7(1): 195, 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38366025
8.
The TvPirin gene is necessary for haustorium development in the parasitic plant Triphysaria versicolor.
Plant Physiol
; 158(2): 1046-53, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22128136
9.
A single-electron reducing quinone oxidoreductase is necessary to induce haustorium development in the root parasitic plant Triphysaria.
Plant Cell
; 22(4): 1404-19, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20424175
10.
Shc Is Implicated in Calreticulin-Mediated Sterile Inflammation in Alcoholic Hepatitis.
Cell Mol Gastroenterol Hepatol
; 15(1): 197-211, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36122677
11.
Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice.
J Biol Chem
; 285(2): 1153-65, 2010 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19892704
12.
Cetylpyridinium chloride is a potent AMP-activated kinase (AMPK) inducer and has therapeutic potential in cancer.
Mitochondrion
; 50: 19-24, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31654752
13.
Novel mTORC1 Inhibitors Kill Glioblastoma Stem Cells.
Pharmaceuticals (Basel)
; 13(12)2020 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33255358
14.
Novel idebenone analogs block Shc's access to insulin receptor to improve insulin sensitivity.
Biomed Pharmacother
; 132: 110823, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33045613
15.
Trans-specific gene silencing between host and parasitic plants.
Plant J
; 56(3): 389-97, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18643992
16.
Small molecules bind human mTOR protein and inhibit mTORC1 specifically.
Biochem Pharmacol
; 155: 298-304, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30028993
17.
In Vitro Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride.
Environ Health Perspect
; 125(8): 087015, 2017 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28885978
18.
Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system.
PLoS One
; 12(6): e0177761, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28586369
19.
A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.
Cell Metab
; 26(3): 539-546.e5, 2017 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28877457
20.
Identification of small molecules that improve ATP synthesis defects conferred by Leber's hereditary optic neuropathy mutations.
Mitochondrion
; 30: 177-86, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27497748