Detalhe da pesquisa
1.
Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer.
Mol Pharmacol
; 98(4): 364-381, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32788222
2.
Phase 1 study of TTC-352 in patients with metastatic breast cancer progressing on endocrine and CDK4/6 inhibitor therapy.
Breast Cancer Res Treat
; 183(3): 617-627, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32696319
3.
G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer.
Breast Cancer Res Treat
; 180(3): 635-646, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32130619
4.
Protein kinase C α enhances migration of breast cancer cells through FOXC2-mediated repression of p120-catenin.
BMC Cancer
; 17(1): 832, 2017 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29216867
5.
Exploring DNA methylation changes in promoter, intragenic, and intergenic regions as early and late events in breast cancer formation.
BMC Cancer
; 15: 816, 2015 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26510686
6.
Extranuclear ERα is associated with regression of T47D PKCα-overexpressing, tamoxifen-resistant breast cancer.
Mol Cancer
; 12: 34, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23634843
7.
Revisiting Estrogen for the Treatment of Endocrine-Resistant Breast Cancer: Novel Therapeutic Approaches.
Cancers (Basel)
; 15(14)2023 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37509308
8.
Retraction Note to: Extranuclear ERα is associated with regression of T47D PKCα-overexpressing, tamoxifen-resistant breast cancer.
Mol Cancer
; 16(1): 121, 2017 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28716023
9.
Endocrine Therapy-Resistant Breast Cancer Cells Are More Sensitive to Ceramide Kinase Inhibition and Elevated Ceramide Levels Than Therapy-Sensitive Breast Cancer Cells.
Cancers (Basel)
; 14(10)2022 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35625985
10.
A Phase Ib Dose Escalation Trial of RO4929097 (a γ-secretase inhibitor) in Combination with Exemestane in Patients with ER + Metastatic Breast Cancer (MBC).
Clin Breast Cancer
; 22(2): 103-114, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34903452
11.
Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer.
Mol Cancer Ther
; 20(1): 11-25, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33177154
12.
Estradiol-induced regression in T47D:A18/PKCalpha tumors requires the estrogen receptor and interaction with the extracellular matrix.
Mol Cancer Res
; 7(4): 498-510, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19372579
13.
Click synthesis of estradiol-cyclodextrin conjugates as cell compartment selective estrogens.
Bioorg Med Chem
; 18(2): 809-21, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20031420
14.
Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib.
J Med Chem
; 63(13): 7186-7210, 2020 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32453591
15.
Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer.
J Med Chem
; 62(24): 11301-11323, 2019 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31746603
16.
Novel Selective Estrogen Receptor Downregulators (SERDs) Developed against Treatment-Resistant Breast Cancer.
J Med Chem
; 60(4): 1325-1342, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28117994
17.
Identification of novel RARbeta2 transcript variants with short 5'-UTRs in normal and cancerous breast epithelial cells.
Oncogene
; 24(7): 1296-301, 2005 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-15558014
18.
Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene.
Cancer Res
; 64(4): 1247-51, 2004 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14973083
19.
Selective Human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer.
J Med Chem
; 59(1): 219-237, 2016 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26681208
20.
The soy isoflavone daidzein improves the capacity of tamoxifen to prevent mammary tumours.
Eur J Cancer
; 41(4): 647-54, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15737570