Detalhe da pesquisa
1.
Reduced synaptic depression in human neurons carrying homozygous disease-causing STXBP1 variant L446F.
Hum Mol Genet
; 33(11): 991-1000, 2024 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38484778
2.
High-throughput assay for regulated secretion of neuropeptides in mouse and human neurons.
J Biol Chem
; 300(6): 107321, 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38677517
3.
Maximal Fusion Capacity and Efficient Replenishment of the Dense Core Vesicle Pool in Hippocampal Neurons.
J Neurosci
; 43(45): 7616-7625, 2023 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37852790
4.
Reduced dynamin-1 levels in neurons lacking MUNC18-1.
J Cell Sci
; 135(22)2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36245272
5.
Power and optimal study design in iPSC-based brain disease modelling.
Mol Psychiatry
; 28(4): 1545-1556, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36385170
6.
Neuromodulator release in neurons requires two functionally redundant calcium sensors.
Proc Natl Acad Sci U S A
; 118(18)2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33903230
7.
SALM1 controls synapse development by promoting F-actin/PIP2-dependent Neurexin clustering.
EMBO J
; 38(17): e101289, 2019 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31368584
8.
CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles.
PLoS Biol
; 18(8): e3000826, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32776935
9.
Munc18-1 is essential for neuropeptide secretion in neurons.
J Neurosci
; 2021 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34103363
10.
Pool size estimations for dense-core vesicles in mammalian CNS neurons.
EMBO J
; 37(20)2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30185408
11.
Loss of MUNC18-1 leads to retrograde transport defects in neurons.
J Neurochem
; 157(3): 450-466, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33259669
12.
Homozygous STXBP1 variant causes encephalopathy and gain-of-function in synaptic transmission.
Brain
; 143(2): 441-451, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31855252
13.
Presynaptic inhibition upon CB1 or mGlu2/3 receptor activation requires ERK/MAPK phosphorylation of Munc18-1.
EMBO J
; 35(11): 1236-50, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27056679
14.
SNAP-25 gene family members differentially support secretory vesicle fusion.
J Cell Sci
; 130(11): 1877-1889, 2017 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28404788
15.
Protein instability, haploinsufficiency, and cortical hyper-excitability underlie STXBP1 encephalopathy.
Brain
; 141(5): 1350-1374, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29538625
16.
Phosphorylation of synaptotagmin-1 controls a post-priming step in PKC-dependent presynaptic plasticity.
Proc Natl Acad Sci U S A
; 113(18): 5095-100, 2016 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27091977
17.
Early Golgi Abnormalities and Neurodegeneration upon Loss of Presynaptic Proteins Munc18-1, Syntaxin-1, or SNAP-25.
J Neurosci
; 37(17): 4525-4539, 2017 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28348137
18.
Dense-core vesicle biogenesis and exocytosis in neurons lacking chromogranins A and B.
J Neurochem
; 144(3): 241-254, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29178418
19.
Munc18-1 mutations that strongly impair SNARE-complex binding support normal synaptic transmission.
EMBO J
; 31(9): 2156-68, 2012 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22446389
20.
Reduced Protein Stability of 11 Pathogenic Missense STXBP1/MUNC18-1 Variants and Improved Disease Prediction.
Biol Psychiatry
; 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490366