Detalhe da pesquisa
1.
Modulation of cofilin phosphorylation by inhibition of the Lim family kinases.
Bioorg Med Chem Lett
; 22(18): 5995-8, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22902653
2.
Long-Acting Tumor-Activated Prodrug of a TGFßR Inhibitor.
J Med Chem
; 64(21): 15787-15798, 2021 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34704759
3.
Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design.
J Med Chem
; 64(19): 14247-14265, 2021 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34543572
4.
Discovery of novel dihydro-9,10-ethano-anthracene carboxamides as glucocorticoid receptor modulators.
Bioorg Med Chem Lett
; 19(8): 2139-43, 2009 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19321341
5.
Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521).
J Med Chem
; 53(9): 3814-30, 2010 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20405922
6.
Multiple and single binding modes of fragment-like kinase inhibitors revealed by molecular modeling, residue type-selective protonation, and nuclear overhauser effects.
J Med Chem
; 51(19): 6225-9, 2008 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18771253
7.
Pyrrolopyridazine MEK inhibitors.
Bioorg Med Chem Lett
; 16(3): 628-32, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16275076
8.
Inhibition of disease progression by a novel retinoid antagonist in animal models of arthritis.
J Rheumatol
; 30(2): 355-63, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12563696
9.
Rational design of RAR-selective ligands revealed by RARbeta crystal stucture.
EMBO Rep
; 5(9): 877-82, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15319780
10.
Aminotriazine 5-HT7 antagonists.
Bioorg Med Chem Lett
; 14(16): 4245-8, 2004 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-15261279