Detalhe da pesquisa
1.
Gatekeeper mutations activate FGF receptor tyrosine kinases by destabilizing the autoinhibited state.
Proc Natl Acad Sci U S A
; 120(8): e2213090120, 2023 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36791110
2.
Inhibition of RAS-driven signaling and tumorigenesis with a pan-RAS monobody targeting the Switch I/II pocket.
Proc Natl Acad Sci U S A
; 119(43): e2204481119, 2022 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36252024
3.
Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.
Nat Chem Biol
; 18(7): 706-712, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35361990
4.
Two FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase Cγ.
Mol Cell
; 61(1): 98-110, 2016 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26687682
5.
Asymmetric protonation of glutamate residues drives a preferred transport pathway in EmrE.
Proc Natl Acad Sci U S A
; 118(41)2021 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34607959
6.
Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation.
Nat Chem Biol
; 16(3): 267-277, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31959966
7.
Programmed Supramolecular Assemblies Using Orthogonal Pairs of Heterodimeric Coiled Coil Peptides.
Angew Chem Int Ed Engl
; 61(27): e202201895, 2022 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35415953
8.
Site-specific resolution of anionic residues in proteins using solid-state NMR spectroscopy.
J Biomol NMR
; 74(6-7): 355-363, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32514875
9.
Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF.
Nucleic Acids Res
; 46(13): 6841-6856, 2018 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29733359
10.
A CURE Biochemistry Laboratory Module to Study Protein-Protein Interactions by NMR Spectroscopy.
J Chem Educ
; 97(2): 437-442, 2020 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34290452
11.
Magnetization transfer in liposome and proteoliposome samples that mimic the protein and lipid composition of myelin.
NMR Biomed
; 32(7): e4097, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31058381
12.
Multiple frequency saturation pulses reduce CEST acquisition time for quantifying conformational exchange in biomolecules.
J Biomol NMR
; 71(1): 19-30, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29796789
13.
Protonation of a glutamate residue modulates the dynamics of the drug transporter EmrE.
Nat Chem Biol
; 12(3): 141-5, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26751516
14.
A structured loop modulates coupling between the substrate-binding and dimerization domains in the multidrug resistance transporter EmrE.
J Biol Chem
; 290(2): 805-14, 2015 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25406320
15.
Correlating lipid bilayer fluidity with sensitivity and resolution of polytopic membrane protein spectra by solid-state NMR spectroscopy.
Biochim Biophys Acta
; 1848(1 Pt B): 334-41, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24835018
16.
A Miniature Protein Stabilized by a Cation-π Interaction Network.
J Am Chem Soc
; 138(5): 1543-50, 2016 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26812069
17.
Allosteric regulation of SERCA by phosphorylation-mediated conformational shift of phospholamban.
Proc Natl Acad Sci U S A
; 110(43): 17338-43, 2013 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24101520
18.
Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling.
Proc Natl Acad Sci U S A
; 110(39): 15602-7, 2013 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24019500
19.
Intrinsic conformational plasticity of native EmrE provides a pathway for multidrug resistance.
J Am Chem Soc
; 136(22): 8072-80, 2014 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24856154
20.
Structural topology of phospholamban pentamer in lipid bilayers by a hybrid solution and solid-state NMR method.
Proc Natl Acad Sci U S A
; 108(22): 9101-6, 2011 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-21576492