RESUMO
PURPOSE: To investigate the relationship between pelvic incidence (PI) and proximal junctional kyphosis (PJK) in patients treated surgically for adult spinal deformity (ASD) with fusion from thoracolumbar junction to sacrum. METHODS: A consecutive series of ASD patients who underwent fusion from the thoracolumbar junction to the sacrum with a minimum of 2-year follow-up was studied. Patients were divided into low PI (≤ 50°) and high PI (> 50°) groups. We compared radiographic parameters and the rates of PJK, between the two groups. A sub-analysis was performed on patients with a postoperative PI minus lumbar lordosis mismatch between - 10° and 10° (i.e., ideally corrected). RESULTS: Sixty-three patients were included: 19 low PI and 44 high PI. Median follow-up was 34 months (range 24-103). Overall PJK rate was 38%. PJK was observed in 16% of low PI and 48% of high PI patients (p = 0.02). The odds ratio for developing PJK with a high PI compared to a low PI was 4.9 (p = 0.03). There were 32 ideally corrected patients. Eleven of these were in the low PI group, and 21 patients were in the high PI group. The incidence of PJK was 25% for ideally corrected patients. PJK occurred in none of these patients in the low PI group and 38% of patients in the high PI group (p = 0.03). CONCLUSION: When the upper-instrumented vertebra includes the thoracolumbar junction, patients with a PI > 50° are at a significantly higher risk of developing PJK compared to patients with a PI ≤ 50°.
Assuntos
Cifose , Anormalidades Musculoesqueléticas , Fusão Vertebral , Adulto , Humanos , Cifose/diagnóstico por imagem , Cifose/epidemiologia , Cifose/cirurgia , Anormalidades Musculoesqueléticas/complicações , Complicações Pós-Operatórias/diagnóstico por imagem , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Estudos Retrospectivos , Fatores de Risco , Fusão Vertebral/efeitos adversos , Vértebras Torácicas/diagnóstico por imagem , Vértebras Torácicas/cirurgiaRESUMO
PURPOSE: This natural history study reports long-term radiographic and clinical outcomes of patients with diagnosis of AIS with curves between 30° and 50°. Our purpose was to determine if any intervention in the natural history is warranted. METHODS: This was a longitudinal descriptive study at a single institution. We reviewed patient factors, radiographic parameters, and patient-reported outcomes at 20- and 30-year follow-up. RESULTS: A total of 31 patients were included. At skeletal maturity (which was the initial point of measurement), the median age was 17 years (range 12-21), the thoracic Cobb angle was 35° ± 5° (maximum-minimum 27°-47°), and the lumbar Cobb angle was 33° ± 7° (maximum-minimum 18°-45°). The median final follow-up was 35 years (median age 52, range 32-61) when the thoracic Cobb angle was 47° ± 12° (maximum-minimum 31°-74°) and the lumbar Cobb angle was 40° ± 17° (maximum-minimum 19°-69°). At final follow-up, 9 (29%) patients had a structural curve > 50°. Ten (32%) patients had a curve from 40° to 49° and 11 (35%) patients had a curve < 40°. The thoracic Cobb angle had progressed from < 40° to > 50° in 5 patients. Thoracolumbar and lumbar Cobb angles progressed from < 40° to greater than > 50° in 1 and 3 patients, respectively. Few patients had functional limitations according to Roland-Morris, Oswestry, and SF36 scores. Pain scores were minimal at final follow-up. CONCLUSION: All AIS curves between 30° and 50° at skeletal maturity tend to progress. Thoracic curves progress more than lumbar curves during the first 20 years and then progression slows down. The opposite happens with lumbar curves. Therefore, the rate of progression decreases with thoracic curves and increases with lumbar curves. Nevertheless, few patients have functional limitations. Further follow-up is necessary to define the true long-term outcome of moderate curves at maturity.
Assuntos
Escoliose , Adolescente , Adulto , Criança , Humanos , Pessoa de Meia-Idade , Adulto Jovem , Vértebras Lombares/diagnóstico por imagem , Região Lombossacral , Radiografia , Escoliose/diagnóstico por imagem , Vértebras Torácicas/diagnóstico por imagemRESUMO
We have previously investigated electromyographic (EMG) and transcranial motor evoked potential (MEP) abnormalities after mechanical spinal cord injury. We now report thermally generated porcine spinal cord injury, characterized by spinal cord generated hindlimb EMG injury activity and spinal cord motor conduction block (MEP loss). Electrocautery (EC) was delivered to thoracic level dural root sleeves within 6-8 mm of the spinal cord (n = 6). Temperature recordings were made near the spinal cord. EMG and MEP were recorded by multiple gluteobiceps intramuscular electrodes before, during, and after EC. Duration of EC was titrated to an end-point of spinal motor conduction block (MEP loss). In 5/6 roots, ipsilateral EMG injury activity was induced by EC. In 4/5 roots, EMG injury activity was identified before MEP loss. In all roots, a minimum of 20 s EC and a temperature maximum of at least 57 °C at the dural root sleeve were required to induce MEP loss. Unexpectedly, conduction block was preceded by an enhanced MEP in 4/6 trials. EMG injury activity, preceding MEP loss, can be seen during near spinal cord EC. Depolarization and facilitation of lumbar motor neurons by thermally excited descending spinal tracts likely explains both hindlimb EMG and an enhanced MEP signal (seen before conduction block) respectively. A thermal mechanism may play a role in some unexplained MEP losses during intraoperative monitoring. EMG recordings might help to detect abnormal discharges and forewarn the monitorist during both mechanical and thermal injury to the spinal cord.
Assuntos
Eletrocoagulação/efeitos adversos , Eletromiografia/métodos , Potencial Evocado Motor/fisiologia , Traumatismos da Medula Espinal/diagnóstico , 1-Propanol/administração & dosagem , Animais , Pressão Sanguínea , Eletrocoagulação/métodos , Desenho de Equipamento , Modelos Animais , Monitorização Intraoperatória , Músculo Esquelético/patologia , Oximetria/métodos , Traumatismos da Medula Espinal/fisiopatologia , Suínos , TemperaturaRESUMO
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA) are attractive targets for transition to the outpatient setting. We assessed the prevalence of rapid responses and major complications in the inpatient setting following 1 or 2-level ACDFs and CDAs. We evaluated factors that may place patients at greater risk for a rapid response or a postoperative complication. METHODS: This was an institutional review board-approved, retrospective cohort study of adults undergoing 1 or 2-level ACDF or CDA at 1 hospital over a 2-year period (2018 and 2019). Data on patient demographic characteristics, surgical procedures, and comorbidities were collected. Rapid response events were identified by hospital floor staff and involved acute changes in a patient's clinical condition. Complications were events that were life-threatening, required an intervention, or led to delayed hospital discharge. RESULTS: In this study, 1,040 patients were included: 888 underwent ACDF and 152 underwent CDA. Thirty-six patients (3.5%) experienced a rapid response event; 22% occurred >24 hours after extubation. Patients having a rapid response event had a significantly higher risk of developing a complication (risk ratio, 10; p < 0.01) and had a significantly longer hospital stay. Twenty-four patients (2.3%) experienced acute complications; 71% occurred >6 hours after extubation. Patients with a complication were older and more likely to be current or former smokers, have chronic obstructive pulmonary disease, have asthma, and have an American Society of Anesthesiologists (ASA) score of >2. The length of the surgical procedure was significantly longer in patients who developed a complication. All patients who developed dysphagia had a surgical procedure involving C4-C5 or more cephalad. Patients with a rapid response event or complication were more commonly undergoing revision surgical procedures. CONCLUSIONS: Rapid response and complications are uncommon following 1 or 2-level ACDFs or CDAs but portend a longer hospital stay and increased morbidity. Revision surgical procedures place patients at higher risk for rapid responses and complications. Additionally, older patients, patients with chronic obstructive pulmonary disease or asthma, patients who are current or former smokers, and patients who have an ASA score of ≥3 are at increased risk for postoperative complications. LEVEL OF EVIDENCE: Prognostic Level III . See Instructions for Authors for a complete description of levels of evidence.
Assuntos
Asma , Doença Pulmonar Obstrutiva Crônica , Fusão Vertebral , Adulto , Humanos , Fusão Vertebral/efeitos adversos , Fusão Vertebral/métodos , Vértebras Cervicais/cirurgia , Pacientes Internados , Pacientes Ambulatoriais , Estudos Retrospectivos , Discotomia/efeitos adversos , Discotomia/métodos , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/cirurgia , Doença Pulmonar Obstrutiva Crônica/complicações , Asma/complicações , Asma/cirurgiaRESUMO
OBJECTIVE: The purpose is to define the origin of radiculopathy of patients with degenerative lumbar scoliosis-stenosis and to assess the correlation between percentage of initial radicular leg pain relief with selective nerve root injections and lateral canal dimensions. DESIGN: Retrospective clinical study. SETTING AND PATIENTS: Thirty-six consecutive patients (average age 72) from Twin Cities Spine Center with degenerative lumbar scoliosis (average major curve 25°) and radicular symptoms were studied. INTERVENTIONS: Patients underwent 46 selective steroid injections of nerve roots concordant with clinical symptomatology. OUTCOME MEASURES: Radiographic measurements included major and lumbosacral curve Cobb angle. Computerized measurements of magnetic resonance imaging (MRI) included minimum subarticular height and foramen cross-sectional area of the nerve roots that were injected. Initial response from the nerve root injections was also rated. RESULTS: Twenty-five percent of nerve root symptoms were coming from the major curve, 72.2% from the lumbosacral hemicurve and 2.8% from both (P<0.001). The affected nerve roots were more frequently the L4 (34.8%) and L5 (28.3%) nerve roots. A total of 71.7% of radicular symptoms were originating from the concavity of the curve and 28.7% from the convexity (P<0.001). The relief from injections was more than 50% in 75% of the patients at 15 days postinjection. There was no statistical significant correlation (P>0.05) between the lateral canal dimensions and the initial response to injection of anesthetic plus steroid injection. CONCLUSIONS: In degenerative lumbar scoliotic curves, radicular symptoms are attributed mainly to nerve roots exiting from the concavity of the lumbosacral hemicurve. No evidence was found that the rate of initial relief from selective nerve root injections correlates with the degree of stenosis noted in the MRI.
Assuntos
Anti-Inflamatórios/uso terapêutico , Radiculopatia/tratamento farmacológico , Radiculopatia/etiologia , Escoliose/complicações , Raízes Nervosas Espinhais , Estenose Espinal/tratamento farmacológico , Estenose Espinal/etiologia , Esteroides/uso terapêutico , Adulto , Idoso , Anti-Inflamatórios/administração & dosagem , Feminino , Fluoroscopia , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Medição da Dor , Radiculopatia/patologia , Estudos Retrospectivos , Escoliose/patologia , Raízes Nervosas Espinhais/diagnóstico por imagem , Esteroides/administração & dosagem , Resultado do TratamentoRESUMO
STUDY DESIGN: Biomechanical Cadaveric Study. OBJECTIVE: To characterize the pullout strength of calcium phosphate cement augmented screws between 0 and 6 minutes after cement injection. SUMMARY OF BACKGROUND DATA: Earlier studies with calcium phosphate cement on pedicle screws inserted into a metal mold or sawbone have shown that the augmentation strength can be affected by the time between cement injection and screw insertion. However, these studies only compared soft cement to completely hardened cement with extended waiting times. These extended waiting times are impractical in live spinal surgeries. METHODS: Twenty-four pedicle screws were inserted and pulled out axially from cadaveric bone to make revision models. The 24 screw holes were randomly divided into 4 groups, with each group having 6 holes. For each group, identical pedicle screws were inserted at 0, 2, 4, and 6 minutes after injection with bioresorbable calcium phosphate cement (CPC). After 24 hours, the augmented screws were pulled out axially and their pullout strengths were compared. RESULTS: The difference between secondary pullout strength and primary pullout strength increased up to 4 minutes after cement injection but decreased after 6 minutes but without statistical difference among the 4 time settings (P>0.3). CONCLUSIONS: The augmented screws had similar fixation strength regardless of the time between cement mixture and screw insertion as long as they are inserted within 6 minutes. Augmentation power tends to increase up to 4 minutes after cement injection but decreases after 6 minutes.
Assuntos
Cimentos Ósseos , Parafusos Ósseos , Fosfatos de Cálcio , Teste de Materiais , Coluna Vertebral/cirurgia , Feminino , Humanos , Fixadores Internos , MasculinoRESUMO
STUDY DESIGN: Biomechanical cadaveric study. OBJECTIVE: To determine the torque required to remove pedicle screws augmented with polymethyl methacrylate (PMMA) or calcium phosphate cement (CPC); thus, proving the safety of back out of augmented screws in the osteopotoric model, which would be a more dangerous setting than the nonosteoporotic model. SUMMARY OF BACKGROUND DATA: To our knowledge, no earlier study has characterized the safety of backing out pedicle screw augmented with PMMA or CPC. METHODS: Pedicle screws were inserted in 24 osteoporotic vertebrae (48 pedicles). The maximal insertion torque and pullout strength of each screw were recorded. After pullout of the pedicle screws, the vertebrae were then randomized into 2 groups of 12 (24 pedicles) each. PMMA was injected into the pedicles in the first group and CPC was injected into the second group after which the pedicle screws were inserted. The pedicle screws were inserted into the pedicle holes augmented with PMMA or CPC, respectively. Finally, all augmented screws were backed out and the maximal removal torque was recorded using a digital torque wrench. RESULTS: Throughout the study, no incidence of pedicle or lamina fractures was observed. The average insertion torque was 0.5±0.27 and 0.45±0.29 N·m for groups 1 and 2, respectively (P=0.724). The average pullout strength was 723.1±391.7 and 671.2±383.0 N (P=0.950). After cement augmentation, the average removal torque was 0.77±0.31 and 0.81±0.26 N·m for PMMA and CPC, respectively (P=0.494). CONCLUSIONS: The results of this study showed that pedicle screws can be easily and safely backed out after augmentation with PMMA or CPC. The result of CPC, however, may only be valid before any bony ingrowth.
Assuntos
Cimentos Ósseos , Parafusos Ósseos , Fosfatos de Cálcio/administração & dosagem , Remoção de Dispositivo/métodos , Polimetil Metacrilato/administração & dosagem , Idoso , Idoso de 80 Anos ou mais , Fenômenos Biomecânicos/fisiologia , Parafusos Ósseos/efeitos adversos , Remoção de Dispositivo/efeitos adversos , Feminino , Humanos , Vértebras Lombares/fisiologia , Vértebras Lombares/cirurgia , Vértebras Torácicas/fisiologia , Vértebras Torácicas/cirurgiaRESUMO
INTRODUCTION: Surgical site infection (SSI) remains a major complication after adult spinal surgery. We investigated whether adding preoperative nasal decontamination by antiseptic swab (skin and nasal antiseptic povidone-iodine, SNA-PI) to our antimicrobial protocol reduces the SSI rate among our patients undergoing thoracolumbar spinal surgery. METHODS: We retrospectively reviewed all adult thoracolumbar spinal surgeries performed between June 2015 and May 2017 at a single hospital. Patients were divided into those who received nasal decontamination (SNA-PI+) and those who did not (SNA-PI-). SSI rates and responsible pathogens were compared between the cohorts. RESULTS: A total of 1,555 surgeries with nasal decontamination (SNA-PI+) and 1,423 surgeries without (SNA-PI-) were included. The SSI rate in the SNA-PI+ group was 13 of 1,555 (0.8%) versus 10 of 1,423 (0.7%) for SNA-PI- group (P = 0.68). The infection rate was the highest among posterior instrumented fusions in the SNA-PI+ group (1.4%). Methicillin-sensitive Staphylococcus aureus was responsible for 70% of infections in the SNA-PI- group and 38% in the SNA-PI+ group (P = 0.13). CONCLUSIONS: Routine nasal antiseptic swab before spine surgery did not affect the overall rate of SSI in thoracolumbar spinal surgeries. The incidence of methicillin-sensitive S aureus was lower in patients who received nasal decontamination (5/1,555, 0.3%) compared with those who did not (7/1,423, 0.5%); however, this result was not statistically significant (P = 0.57).
Assuntos
Anti-Infecciosos Locais , Infecções Estafilocócicas , Adulto , Humanos , Povidona-Iodo/uso terapêutico , Estudos Retrospectivos , Infecção da Ferida Cirúrgica/epidemiologiaRESUMO
Successful placement of cervical pedicle screws requires accurate identification of both entry point and trajectory. However, literature has not provided consistent recommendations regarding the direction of pedicle screw insertion and entry point location. The objective of this study was to define a guideline regarding the optimal entry point and trajectory in placing subaxial cervical pedicle screws and to evaluate the screw accuracy in cadaver cervical spines. The guideline for entry point and trajectory for each vertebra was established based on the recently published morphometric data. Six fresh frozen cervical spines (C3-C7) were used. There were two men and four women. After posterior exposure, the entry point was determined and the cortical bone of the entry point was removed using a 2-mm burr. Pilot holes were created with a cervical probe based on the guideline using fluoroscopy. After tapping, 3.5-mm screws with appropriate length were inserted. After screw insertion, every vertebra was dissected and inspected for pedicle breach. The pedicle width, height, pedicle transverse angulation and actual screw insertion angle were measured. A total of 60 pedicle screws were inserted. No statistical difference in pedicle width and height was found between the left and right sides for each level. The overall accuracy of pedicle screws was 83.3%. The remaining 13.3% screws had noncritical breach, and 3.3% had critical breach. The critical breach was not caused by the guideline. There was no statistical difference between the pedicle transverse angulation and the actual screw trajectory created using the guideline. There was statistical difference in pedicle width between the breach and non-breach screws. In conclusion, high success rate of subaxial cervical pedicle screw placement can be achieved using the recently proposed operative guideline and oblique views of fluoroscopy. However, careful preoperative planning and good surgical skills are still required to ensure screw placement accuracy and to reduce the risk of neural and vascular injury.
Assuntos
Parafusos Ósseos/normas , Vértebras Cervicais/cirurgia , Avaliação de Resultados em Cuidados de Saúde/métodos , Complicações Pós-Operatórias/prevenção & controle , Fusão Vertebral/instrumentação , Fusão Vertebral/métodos , Idoso , Antropometria , Cadáver , Vértebras Cervicais/anatomia & histologia , Vértebras Cervicais/diagnóstico por imagem , Dissecação/métodos , Feminino , Fluoroscopia/métodos , Fluoroscopia/normas , Humanos , Doença Iatrogênica/prevenção & controle , Masculino , Complicações Pós-Operatórias/diagnóstico por imagem , Complicações Pós-Operatórias/etiologia , Cuidados Pré-Operatórios/métodosRESUMO
Pedicle screws are placed using pilot holes. The trajectory of pilot holes can be verified by pedicle sounding or radiographs. However, a pilot hole alone does not insure that the screw will follow the pilot hole. No studies have characterized the risk of misalignment of a pedicle screw with respect to its pilot hole trajectory. The objective of this study was to measure the misalignment angles between pedicle screws and pilot holes with or without tapping. Six human cadaveric thoracic spines were used. One hundred and forty pilot holes were created with a straight probe. Steel wires were temporarily inserted and their positions were recorded with CT scans. The left pedicles were tapped with 4.5 mm fluted tap and the right pedicles remained untapped. Pedicle screws (5.5 mm) were inserted into the tapped and untapped pedicles followed by CT scans. The trajectories of pilot holes and screws were calculated using three-dimensional vector analysis. A total of 133 pilot holes (95%) were inside pedicles. For the untapped side, 14 out of 68 (20%) screws did not follow the pilot holes and were outside the pedicles. For the tapped side, 2 out of 65 (3%) did not follow and breached the pedicles. The average misalignment angles between the screw and pilot hole trajectory were 7.7 degrees +/- 6.5 degrees and 5.6 degrees +/- 3.2 degrees for the untapped side and tapped side, respectively (P < 0.05). Most pedicle screws had lateral screw breach (13 out of 16) whereas most pilot holes had medial pedicle breach (6 out of 7). Tapping of pilot holes (1 mm undertap) helps align pedicle screws and reduces the risk of screw malposition. Although most pedicle screws had lateral breach, the risk of medial pedicle breach of the pilot holes must be recognized.
Assuntos
Parafusos Ósseos/normas , Doenças da Coluna Vertebral/cirurgia , Fusão Vertebral/instrumentação , Fusão Vertebral/métodos , Coluna Vertebral/cirurgia , Vértebras Torácicas/cirurgia , Idoso , Cadáver , Desenho de Equipamento/métodos , Falha de Equipamento , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/patologia , Complicações Pós-Operatórias/fisiopatologia , Complicações Pós-Operatórias/prevenção & controle , Coluna Vertebral/anatomia & histologia , Coluna Vertebral/diagnóstico por imagem , Vértebras Torácicas/anatomia & histologia , Vértebras Torácicas/diagnóstico por imagem , Tomografia Computadorizada por Raios XRESUMO
STUDY DESIGN: An in vitro biomechanical study using osteoporotic cadaveric vertebrae. OBJECTIVE: To compare the biomechanics of transpedicular and extrapedicular approaches in polymethylmethacrylate vertebroplasty in terms of height restoration, strength, and stiffness. SUMMARY BACKGROUND DATA: Cement is typically injected through a transpedicular approach in both vertebroplasty and kyphoplasty procedures. Previous biomechanical studies were primarily focused on the transpedicular approach. Extrapedicular approach has been recently developed to provide more symmetric cement filling and has good clinical results. However, no biomechanical data are available to compare these 2 techniques. METHODS: Twenty-four osteoporotic vertebral bodies were randomly divided into 2 groups for either transpedicular or extrapedicular vertebroplasty. Six lumbar and 6 thoracic vertebrae were used for each group. Each vertebral body was compressed by 25% of its original height and its strength and stiffness were measured. The vertebral bodies were treated with polymethylmethacrylate using either transpedicular or extrapedicular approach. The height restoration was measured before the treated vertebrae were recompressed to determine posttreatment strength and stiffness. RESULTS: Both techniques increased vertebral strength by approximately 50% of the intact strength. There was no statistical difference in posttreatment strength between these 2 techniques. However, the transpedicular technique had higher stiffness recovery (70% to 80%) from the intact stiffness than the extrapedicular technique (60%). The extrapedicular approach achieved greater height restoration in thoracic vertebrae. CONCLUSIONS: Both extrapedicular and transpedicular techniques increased strength but reduced stiffness compared with the intact condition. The extrapedicular technique achieved greater height restoration possibly attributed to its easier access to the fracture site. These biomechanical data provide useful information when selecting an approach for cement injection in vertebroplasty procedures.
Assuntos
Vértebras Lombares/cirurgia , Osteoporose/cirurgia , Polimetil Metacrilato/uso terapêutico , Vértebras Torácicas/cirurgia , Vertebroplastia , Idoso , Idoso de 80 Anos ou mais , Fenômenos Biomecânicos , Cimentos Ósseos/uso terapêutico , Força Compressiva , Feminino , Humanos , Vértebras Lombares/fisiopatologia , Masculino , Osteoporose/fisiopatologia , Estresse Mecânico , Vértebras Torácicas/fisiopatologia , Suporte de CargaRESUMO
Single level axial lumbar interbody fusion (AxiaLIF) using a transsacral rod through a paracoccygeal approach has been developed with promising early clinical results and biomechanical stability. Recently, the transsacral rod has been extended to perform a two-level fusion at both L4-L5 and L5-S1 levels (AxiaLIF II). No biomechanical studies have been conducted on multilevel fusion using the AxiaLIF technique. In this study, the biomechanics of L4-S1 motion segments instrumented with the AxiaLIF II transsacral rod was evaluated. Six human cadaveric lumbosacral spine segments from L4 to S1 were used (age ranges 46-74 years). Unconstrained and non-destructive pure moments in axial torsion, lateral bending, and flexion extension were applied to each specimen following intact, standalone AxiaLIF II, and AxiaLIF II with two posterior fixation options: facet screws and pedicle screws with rods. Range of motion was calculated from the raw data collected with an optical motion tracking system. The two-level transsacral rod was successfully inserted in all the specimens. At L4-L5 level in axial torsion (AT) and flexion extension (FE), none of the surgical treatments showed statistically significant difference between the procedures (all P > 0.05) although facet screws and pedicle screws had higher stability on average. In lateral bending (LB), the two posterior fixation techniques had significantly higher construct stability (P < 0.05) than the standalone rod. No significant difference was found between facet screws and pedicle screws (P = 0.821). At L5-S1 level in AT and LB, none of the surgical treatments were found to be statistically significant (all P > 0.05). In FE, standalone two-level transsacral rod had significantly higher range of motion (ROM) compared with the posterior fixation techniques (P < 0.05). In conclusion, the standalone rod reduced intact ROM significantly. Supplementary fixations including facet screws and pedicle screws are required to achieve higher construct stability for successful fusion. Further clinical studies are essential to evaluate the practical success of this technique.
Assuntos
Fixadores Internos/tendências , Vértebras Lombares/fisiologia , Vértebras Lombares/cirurgia , Amplitude de Movimento Articular/fisiologia , Fusão Vertebral/instrumentação , Fusão Vertebral/métodos , Idoso , Fenômenos Biomecânicos/fisiologia , Parafusos Ósseos/normas , Parafusos Ósseos/tendências , Cadáver , Feminino , Humanos , Processamento de Imagem Assistida por Computador/métodos , Fixadores Internos/normas , Vértebras Lombares/anatomia & histologia , Masculino , Pessoa de Meia-Idade , Óptica e Fotônica/métodos , Sacro/anatomia & histologia , Sacro/fisiologia , Sacro/cirurgia , Doenças da Coluna Vertebral/cirurgia , Estresse Mecânico , Gravação em Vídeo/métodos , Suporte de Carga/fisiologia , Articulação Zigapofisária/anatomia & histologia , Articulação Zigapofisária/fisiologia , Articulação Zigapofisária/cirurgiaRESUMO
Abundant data are available for direct anterior/posterior spine fusion (APF) and some for transforaminal lumbar interbody fusion (TLIF), but only few studies from one institution compares the two techniques. One-hundred and thirty-three patients were retrospectively analyzed, 68 having APF and 65 having TLIF. All patients had symptomatic disc degeneration of the lumbar spine. Only those with one or two-level surgeries were included. Clinical chart and radiologic reviews were done, fusion solidity assessed, and functional outcomes determined by pre- and postoperative SF-36 and postoperative Oswestry Disability Index (ODI), and a satisfaction questionnaire. The minimum follow-up was 24 months. The mean operating room time and hospital length of stay were less in the TLIF group. The blood loss was slightly less in the TLIF group (409 vs. 480 cc.). Intra-operative complications were higher in the APF group, mostly due to vein lacerations in the anterior retroperitoneal approach. Postoperative complications were higher in the TLIF group due to graft material extruding against the nerve root or wound drainage. The pseudarthrosis rate was statistically equal (APF 17.6% and TLIF 23.1%) and was higher than most published reports. Significant improvements were noted in both groups for the SF-36 questionnaires. The mean ODI scores at follow-up were 33.5 for the APF and 39.5 for the TLIF group. The patient satisfaction rate was equal for the two groups.
Assuntos
Disco Intervertebral/cirurgia , Doenças da Coluna Vertebral/cirurgia , Fusão Vertebral/métodos , Adolescente , Adulto , Idoso , Feminino , Humanos , Tempo de Internação , Vértebras Lombares , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Complicações Pós-Operatórias , Estudos Retrospectivos , Inquéritos e Questionários , Resultado do TratamentoRESUMO
OBJECT: Porcine spinal cords were mechanically injured at the thoracic level while recording muscle-derived electrically stimulated transcranial motor evoked potentials (TcMEPs) and electromyography (EMG) readings from the same electrode derivations. The authors postulated that midthoracic spinal cord injury caused by diverse methods can trigger hindlimb EMG activity. Early detection of hindlimb EMG activity may permit avoidance of motor conduction block (TcMEP loss). METHODS: Twelve pigs underwent midthoracic spinal cord exposure. Spinal cord sectioning was performed to define dorsal column versus lateral spinal cord contribution to muscle-derived electrically stimulated spinal cord motor evoked potentials (SC MEPs) and TcMEPs (in 2 pigs). A bipolar needle stimulator was placed within intramedullary sites to 1) acquire electrically stimulated motor evoked potentials in the hindlimbs, and 2) induce mechanically stimulated hindlimb EMG activity at sites responsive to electrical stimulation (in 2 pigs). Transcranial MEPs and EMG recordings were observed during spinal cord distraction (in 3 pigs), slow and rapid extradural spinal cord compression with a metal caliper (in 3 pigs), and rapid extradural spinal cord compression with a spring-loaded clip (in 2 pigs). RESULTS: Lateral cord (but not dorsal column) sectioning abolished both SC MEPs and TcMEPs. Intramedullary electrical and mechanical stimulation within the lateral (but not dorsal) cord elicited ipsilateral hindlimb MEPs and EMG activity ("EMG injury discharge"), respectively. Distraction inconsistently produced EMG injury discharges concomitant with TcMEP loss. Rapid extradural spinal cord compression with a metal caliper or spring-loaded clip consistently induced EMG injury discharges (in 4 of 4 pigs); slow compression did not elicit EMG activity. Brief extradural spring-loaded clip compressions (1-2 seconds) elicited EMG injury discharges without TcMEP loss; 14-second clip compression effected EMG injury discharges and TcMEP loss, which recovered after clip removal. CONCLUSIONS: Electromyographic activity (referred to as "EMG injury discharges" in the present study) can be elicited both by intramedullary manipulation and rapidly applied transaxial spinal cord compression. Preliminary observations suggest that these EMG injury discharges precede and may anticipate TcMEP loss. Presumably, rapid deformation of spinal motor tracts (which appear to lie within the lateral porcine spinal cord) generates descending volleys which can bring to firing threshold lumbar motor neurons (and recording of EMG injury discharges). Intraoperative neuromonitoring of high-risk spinal surgeries at the spinal cord level may benefit from the addition of EMG recording to tests of spinal cord motor conduction such as TcMEP. Further clinical trials are required to examine EMG efficacy in this context.
Assuntos
Eletromiografia , Potencial Evocado Motor/fisiologia , Tratos Piramidais/lesões , Traumatismos da Medula Espinal/diagnóstico , Traumatismos da Medula Espinal/fisiopatologia , Animais , Modelos Animais de Doenças , Estimulação Elétrica , Membro Posterior , Suínos , Vértebras TorácicasRESUMO
STUDY DESIGN: Retrospective comparative study of 2 approaches to multilevel fusion for cervical spondylosis in consecutive patients at a single institution. OBJECTIVE: To provide justification for a concomitant posterior approach in multilevel cervical fusion for spondylosis by demonstrating decreased pseudarthrosis and reoperation rates. SUMMARY OF BACKGROUND DATA: Among the factors that affect cervical rates is the number of levels, such that increasing the number of levels leads to lower fusion rates. Because of this, modifications have been sought to improve union in multilevel procedures. One option is an antero-posterior (AP) approach or circumferential arthrodesis. METHODS: Seventy-eight consecutive patients who underwent multilevel cervical fusion at a single institution and with minimum 2-year follow-up data were divided into an anterior-only group (anterior: n=55), and an AP group (AP: n=23). Union was assessed by surgical exploration, computerized tomography scan, and flexion-extension radiographs. The groups were compared in terms of pseudarthrosis rates and reoperation rates. RESULTS: Using chi(2) analysis, there was a significant difference in pseudarthrosis rates (anterior 38% vs. AP 0%; P<0.001), and reoperation rate for pseudarthrosis (anterior 22% vs. AP 0%; P=0.01). There were no differences in overall (anterior 36% vs. AP 30%; P=0.62) and early (anterior 15% vs. AP 26%; P=0.13) reoperation rates, but late reoperations were increased in the anterior group (24% vs. AP 4%; P=0.043). CONCLUSIONS: A concomitant posterior fusion significantly reduced the incidence of pseudarthrosis (0% vs. 38%) and pseudarthrosis-related reoperations (0% vs. 22%) compared with traditional anterior-only fusion. However, this did not translate to a difference in overall reoperation rates. The majority of reoperations in the AP group (86%) were performed within 6 months, whereas those in the anterior-only group (65%) were performed later, which was generally when a pseudarthrosis became evident.
Assuntos
Vértebras Cervicais/cirurgia , Complicações Pós-Operatórias/epidemiologia , Fusão Vertebral/métodos , Espondilose/cirurgia , Adulto , Vértebras Cervicais/diagnóstico por imagem , Vértebras Cervicais/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Avaliação de Resultados em Cuidados de Saúde , Complicações Pós-Operatórias/prevenção & controle , Pseudoartrose/epidemiologia , Pseudoartrose/prevenção & controle , Radiografia , Reoperação/estatística & dados numéricos , Estudos Retrospectivos , Prevenção Secundária , Fusão Vertebral/estatística & dados numéricos , Espondilose/diagnóstico por imagem , Espondilose/patologia , Fatores de Tempo , Resultado do TratamentoRESUMO
STUDY DESIGN: This is a retrospective cohort study. OBJECTIVE: To compare posterolateral versus transforaminal interbody fusion (PLF vs. PLF+TLIF) of the L4/5 segment regarding rates of subsequent surgery, clinical and radiographic parameters, and patient satisfaction. SUMMARY OF BACKGROUND DATA: Surgical treatment of lumbar stenosis, decompression with or without fusion, is an efficacious treatment in select patients. Reoperation is thought to be a problem after lumbar fusion. Despite multiple studies, the fusion method that minimizes the need for subsequent surgery has yet to be determined. MATERIALS AND METHODS: A retrospective cohort study was conducted on 89 patients who had an isolated L4/5 decompression and fusion, from January 2006 to 2012. All patients had stenosis and degenerative spondylolisthesis at the L4/5 level. All surgeries were performed at a single center, using either PLF (31 patients) or PLF+TLIF (58 patients) techniques. Preoperative and postoperative patient-reported outcome measures (Oswestry disability index, visual analog scale back pain, visual analog scale leg pain) and radiographic parameters (L4/5 lordosis and overall lumbar lordosis) were measured. Patient satisfaction was acquired via a questionnaire. Chart reviews and patient questionnaires were used to determine the incidence of subsequent lumbar surgery over a minimum follow-up of 5 years. RESULTS: At an average of 8.7 years follow-up, 2 of 31 patients in the PLF group had subsequent lumbar surgery, compared with 16 of 58 patients in the PLF+TLIF group (6% vs. 28%; P=0.02). There were no significant differences between groups with respect to sex, age, body mass index, tobacco, perioperative measures, patient-reported outcomes, or radiographic parameters (P>0.05). CONCLUSIONS: Both PLF and PLF+TLIF are effective fusion methods for L4/5 stenosis and spondylolisthesis. In this study, patients treated with PLF were less likely to undergo a subsequent lumbar surgery. More research is needed to determine which factors influence whether PLF or PLF+TLIF should be used in these patients. LEVEL OF EVIDENCE: Level III.
Assuntos
Vértebras Lombares/cirurgia , Fusão Vertebral/métodos , Feminino , Humanos , Estimativa de Kaplan-Meier , Vértebras Lombares/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Qualidade de VidaRESUMO
BACKGROUND: Prior biomechanical studies of transforaminal lumbar interbody fusion were primarily focused on various posterior instrumentation options, comparison with other fusion techniques, and cage positioning inside disc space. Few studies investigated the biomechanics of various cage designs in terms of construct stability. METHODS: Twelve lumbar motion segments were used in this study. The experimental procedure has two steps: multidirectional flexibility test and cyclic test. In the multidirectional flexibility test, all twelve specimens were tested following intact and five different cages (straight or banana shaped). The straight cages had biconvex or flat profile. In the cyclic test, the twelve specimens were randomly divided into two groups for biconvex and flat cages. Three thousand cycles in axial torsion, lateral bending and flexion extension were applied sequentially and cage migration was measured. FINDINGS: On average, the cage and posterior fixation reduced the range of motion of the intact condition by 40%, 69% and 75% in axial torsion, lateral bending and flexion extension, respectively. There was no statistical difference in construct stability among all five cages. The cage migration (biconvex vs flat) under cyclic loading was less than 0.2mm and no statistical difference was found. INTERPRETATION: The experimental results suggest that the geometry of cages, including shape (banana or straight), length, and surface profile (biconvex or flat), does not affect construct stability when the cages are used in conjunction with posterior fixation. With posterior fixation and surface serration, cage migration was minimal under cyclic loading for both biconvex and flat cages.
Assuntos
Fixadores Internos , Vértebras Lombares/cirurgia , Região Lombossacral/cirurgia , Desenho de Prótese/métodos , Fusão Vertebral/instrumentação , Fusão Vertebral/métodos , Idoso , Fenômenos Biomecânicos , Cadáver , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Modelos Biológicos , Desenho de Prótese/instrumentaçãoRESUMO
STUDY DESIGN: A study documenting major complications encountered in revision procedures for lumbar cage pseudoarthrosis. OBJECTIVE: To document the perioperative complications associated with revision surgery for threaded cylindrical cage pseudoarthrosis. SUMMARY OF BACKGROUND DATA: Pseudoarthrosis after cylindrical cage placement manifests as persistent or recurrent pain and disability after surgery. Revision strategies include isolated posterior stabilization and posterior bone grafting, versus circumferential revision where an attempt is made to remove the cages anteriorly, followed by posterior stabilization and fusion. Potential complications associated with these revision procedures have not been adequately documented in the past. METHODS: Forty-seven consecutive patients with the diagnosis of cylindrical cage pseudoarthrosis were surgically treated with either a circumferential revision (AP) or an isolated posterior instrumented fusion (P). All intraoperative and postoperative complications were documented. Radiographic interbody fusion rates and preoperative and postoperative visual analog scale (VAS) scores were documented. RESULTS: Three of the AP patients, all with anterior cage placement at L5-S1, had iliac vein lacerations requiring repair. A fourth patient had a ureteral injury requiring subsequent nephrectomy. Three patients who underwent circumferential revision and 2 patients who had an isolated posterior procedure had postoperative complications, including 2 infections (1 AP and 1 P), 1 radiculopathy (P), and 2 patients with prolonged ileus (both AP). There was a statistically significant decrease in overall VAS scores postoperatively for the 2 groups using the paired t test (P<0.0001). There was no difference in either the preoperative (P=0.22) or 2-year postoperative (P=0.30) VAS scores between the AP and P groups [rank-sum (Mann-Whitney) t tests]. Interbody fusion was achieved in 79% (30 of 38 levels) in the AP group. The interbody fusion rate was 37% (8 of 22) for the P group. CONCLUSIONS: Circumferential revision including cage removal, structural allograft placement, and posterior stabilization is associated with increased perioperative complications. Although an anterior approach showed increased interbody fusion rates, this technique did not lead to more superior clinical outcomes based on VAS scores. It remains to be shown by larger prospective studies if there is a true difference in outcome between these 2 groups that will justify the increased perioperative morbidity associated with attempted cage removal.
Assuntos
Artrodese/efeitos adversos , Vértebras Lombares/cirurgia , Pseudoartrose/cirurgia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Assistência Perioperatória/efeitos adversos , Reoperação/efeitos adversos , Fusão Vertebral/efeitos adversos , Resultado do Tratamento , Adulto JovemRESUMO
STUDY DESIGN: This is a retrospective cohort study. OBJECTIVE: This study aimed to determine whether the Fusion Risk Score (FRS) is valid for perioperative complications. SUMMARY OF BACKGROUND DATA: The FRS was previously formulated from a retrospective review of 364 fusion surgeries in patients over age 65. Patient demographics, comorbidities, surgical approach, levels, and osteotomies are incorporated in a weighted manner. This score correlated well with the risk of perioperative complications, operative time, estimated blood loss during surgery, and length of hospital stay. MATERIALS AND METHODS: A new cohort of patients was studied. Subjects were 65 years old or older and had undergone routine elective thoracic or lumbar fusion surgery. The FRS was calculated for each subject to estimate risk (low, medium, or high) for perioperative complications. Actual incidences of major complications in the first 90 days after the surgery were noted and statistically compared with the predicted risk. The FRS was compared with intensive care unit admittance, estimated blood loss, operative time, and hospital length of stay to determine whether the score was predictive. RESULTS: In total, 51% of our patients were at low risk (FRS, 1-3) for perioperative complications; 43% were at medium risk (FRS, 4-9); and 7% were at high risk (FRS, over 9). A total of 8% in the low-risk group, 23% in the medium-risk group, and 67% in the high-risk group actually developed significant perioperative complications. Medium-risk and high-risk patients experienced proportionally more perioperative complications than did low-risk patients; the difference was highly statistically significant. CONCLUSIONS: This study validated the association between the FRS and complications in the first 90 days after thoracolumbar spinal fusion surgery on the basis of patient and surgery characteristics. It also predicts the risk of intensive care unit admission, operative time, blood loss, and hospital length of stay.
Assuntos
Vértebras Lombares/cirurgia , Fusão Vertebral , Vértebras Torácicas/cirurgia , Idoso , Idoso de 80 Anos ou mais , Perda Sanguínea Cirúrgica , Humanos , Unidades de Terapia Intensiva , Tempo de Internação , Complicações Pós-Operatórias/etiologia , Valor Preditivo dos Testes , Medição de Risco , Fatores de Risco , Fusão Vertebral/efeitos adversosRESUMO
STUDY DESIGN: This study retrospectively reviewed recurrences of surgical site infections (SSI) in spinal patients treated with vacuum-assisted closure (VAC) technology. OBJECTIVE: Identify patient and treatment factors associated with recurrence of SSI after VAC treatment. SUMMARY OF BACKGROUND DATA: Patients treated with VAC can achieve healing of deep spine wound infections; however, some patients develop a recurrent infection. Risk factors associated with a recurrence have not been identified. MATERIALS AND METHODS: One hundred and eleven patients with SSI after spine surgery from 2002 to 2010 were studied. They had been treated with irrigation and debridement, placement of VAC, and IV antibiotics. They subsequently were taken to surgery for primary closure of their wound. Patients with SSI who healed after the initial infection treatment were compared with patients who experienced recurrence. Patient and treatment factors that were studied included smoking status, body mass index, obesity status, diagnosis of diabetes, fusion surgery, methicillin-resistant Staphylococcus aureus, or polybacteria infection, number of irrigation and debridement treatments before closure, duration of IV antibiotic treatment, and duration of treatment time with VAC. Patients with SSI who healed after the initial treatment were compared with patients who experienced recurrence. RESULTS: Fourteen patients had at least one recurrence of wound infection. None of the patient or treatment factors was associated with the recurrence of a SSI. CONCLUSIONS: Among spine surgery patients with a SSI treated with the VAC system, those factors which predispose a patient to develop a recurrent SSI remain unknown. LEVEL OF STUDY: Level IV.