Detalhe da pesquisa
1.
Disruption of cellular proteostasis by H1N1 influenza A virus causes α-synuclein aggregation.
Proc Natl Acad Sci U S A
; 117(12): 6741-6751, 2020 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152117
2.
Disrupted-in-schizophrenia 1 protein aggregates in cerebrospinal fluid are elevated in patients with first-episode psychosis.
Psychiatry Clin Neurosci
; 77(12): 665-671, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37668563
3.
Disrupted-in-schizophrenia 1 overexpression disrupts hippocampal coding and oscillatory synchronization.
Hippocampus
; 29(9): 802-816, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30723982
4.
DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites.
J Biol Chem
; 291(2): 613-29, 2016 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26553875
5.
Intra-nasal dopamine alleviates cognitive deficits in tgDISC1 rats which overexpress the human DISC1 gene.
Neurobiol Learn Mem
; 146: 12-20, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29107702
6.
Neuropeptide precursor VGF is genetically associated with social anhedonia and underrepresented in the brain of major mental illness: its downregulation by DISC1.
Hum Mol Genet
; 23(22): 5859-65, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24934694
7.
Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits.
Hum Mol Genet
; 21(20): 4406-18, 2012 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22798627
8.
50-kHz ultrasonic vocalizations do not signal social anhedonia in transgenic DISC1 rats.
Brain Behav
; 13(5): e2984, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37016810
9.
Social anhedonia as a Disrupted-in-Schizophrenia 1-dependent phenotype.
Sci Rep
; 12(1): 10182, 2022 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35715502
10.
Disrupted-in-schizophrenia 1 Protein Misassembly Impairs Cognitive Flexibility and Social Behaviors in a Transgenic Rat Model.
Neuroscience
; 493: 41-51, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35461978
11.
Viruses as 'Truffle Hounds': Molecular Tools for Untangling Brain Cellular Pathology.
Trends Neurosci
; 44(5): 352-365, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33317827
12.
Disrupted in Schizophrenia 1 regulates the processing of reelin in the perinatal cortex.
Schizophr Res
; 215: 506-513, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28433501
13.
Oligomer assembly of the C-terminal DISC1 domain (640-854) is controlled by self-association motifs and disease-associated polymorphism S704C.
Biochemistry
; 48(32): 7746-55, 2009 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19583211
14.
Anxiogenic-like behavior and deficient attention/working memory in rats expressing the human DISC1 gene.
Pharmacol Biochem Behav
; 179: 73-79, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30779934
15.
Disrupted-in-schizophrenia 1 functional polymorphisms and D2 /D3 receptor availability: A [11 C]-(+)-PHNO imaging study.
Genes Brain Behav
; 18(8): e12596, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31264367
16.
Dysregulation of a specific immune-related network of genes biologically defines a subset of schizophrenia.
Transl Psychiatry
; 9(1): 156, 2019 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31150013
17.
Quantitative Proteomics of Synaptosomal Fractions in a Rat Overexpressing Human DISC1 Gene Indicates Profound Synaptic Dysregulation in the Dorsal Striatum.
Front Mol Neurosci
; 11: 26, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29467617
18.
Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein.
PLoS One
; 13(1): e0191162, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29324815
19.
Simultaneous effects on parvalbumin-positive interneuron and dopaminergic system development in a transgenic rat model for sporadic schizophrenia.
Sci Rep
; 6: 34946, 2016 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27721451
20.
Peripheral DISC1 protein levels as a trait marker for schizophrenia and modulating effects of nicotine.
Behav Brain Res
; 275: 176-82, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25218871