Detalhe da pesquisa
1.
Partial response or better at six months is prognostic of superior progression-free survival in Waldenström macroglobulinaemia patients treated with ibrutinib.
Br J Haematol
; 192(3): 542-550, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33207010
2.
Genomic evolution of ibrutinib-resistant clones in Waldenström macroglobulinaemia.
Br J Haematol
; 189(6): 1165-1170, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32103491
3.
CXCR4 WHIM-like frameshift and nonsense mutations promote ibrutinib resistance but do not supplant MYD88(L265P) -directed survival signalling in Waldenström macroglobulinaemia cells.
Br J Haematol
; 168(5): 701-7, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25371371
4.
MYD88 mutated and wild-type Waldenström's Macroglobulinemia: characterization of chromosome 6q gene losses and their mutual exclusivity with mutations in CXCR4.
Haematologica
; 103(9): e408-e411, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29599202
5.
CXCL13 levels are elevated in patients with Waldenström macroglobulinemia, and are predictive of major response to ibrutinib.
Haematologica
; 102(11): e452-e455, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28798070
6.
A new role for the SRC family kinase HCK as a driver of SYK activation in MYD88 mutated lymphomas.
Blood Adv
; 6(11): 3332-3338, 2022 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35255496
7.
The BCL2 antagonist ABT-199 triggers apoptosis, and augments ibrutinib and idelalisib mediated cytotoxicity in CXCR4 Wild-type and CXCR4 WHIM mutated Waldenstrom macroglobulinaemia cells.
Br J Haematol
; 170(1): 134-8, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25582069
8.
Expression of the prosurvival kinase HCK requires PAX5 and mutated MYD88 signaling in MYD88-driven B-cell lymphomas.
Blood Adv
; 4(1): 141-153, 2020 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31935288
9.
SYK is activated by mutated MYD88 and drives pro-survival signaling in MYD88 driven B-cell lymphomas.
Blood Cancer J
; 10(1): 12, 2020 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32005797
10.
Insights into the genomic landscape of MYD88 wild-type Waldenström macroglobulinemia.
Blood Adv
; 2(21): 2937-2946, 2018 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30401751
11.
Comparative genomics of CXCR4MUT and CXCR4WT single cells in Waldenström's macroglobulinemia.
Blood Adv
; 4(18): 4550-4553, 2020 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32956451