Detalhe da pesquisa
1.
Activation of cytotoxic lymphocytes through CD6 enhances killing of cancer cells.
Cancer Immunol Immunother
; 73(2): 34, 2024 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38280067
2.
Siponimod Attenuates Neuronal Cell Death Triggered by Neuroinflammation via NFκB and Mitochondrial Pathways.
Int J Mol Sci
; 25(5)2024 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38473703
3.
Role of cellular senescence in the pathogenesis of systemic sclerosis.
Curr Opin Rheumatol
; 34(6): 343-350, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35979691
4.
Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma.
Proc Natl Acad Sci U S A
; 116(9): 3695-3702, 2019 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30755532
5.
Glycoprotein nonmetastatic melanoma protein B: A key mediator and an emerging therapeutic target in autoimmune diseases.
FASEB J
; 34(7): 8810-8823, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32445534
6.
Hypomethylation of STAT1 and HLA-DRB1 is associated with type-I interferon-dependent HLA-DRB1 expression in lupus CD8+ T cells.
Ann Rheum Dis
; 78(4): 519-528, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30674474
7.
Epigenetic Control of Scleroderma: Current Knowledge and Future Perspectives.
Curr Rheumatol Rep
; 21(12): 69, 2019 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31813068
8.
Caffeine inhibits STAT1 signaling and downregulates inflammatory pathways involved in autoimmunity.
Clin Immunol
; 192: 68-77, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29678503
9.
Methyl-CpG-binding protein 2 mediates antifibrotic effects in scleroderma fibroblasts.
Ann Rheum Dis
; 77(8): 1208-1218, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29760157
10.
Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa.
Ann Rheum Dis
; 77(11): 1653-1664, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30021804
11.
CD4+CD28+KIR+CD11ahi T cells correlate with disease activity and are characterized by a pro-inflammatory epigenetic and transcriptional profile in lupus patients.
J Autoimmun
; 86: 19-28, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29066026
12.
Unfolding the pathogenesis of scleroderma through genomics and epigenomics.
J Autoimmun
; 83: 73-94, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28526340
13.
Scleroderma keratinocytes promote fibroblast activation independent of transforming growth factor beta.
Rheumatology (Oxford)
; 56(11): 1970-1981, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28968684
14.
Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma.
Bioorg Med Chem Lett
; 27(8): 1744-1749, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28285914
15.
Scleroderma dermal microvascular endothelial cells exhibit defective response to pro-angiogenic chemokines.
Rheumatology (Oxford)
; 55(4): 745-54, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26705326
16.
Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies.
Ann Rheum Dis
; 74(8): 1612-20, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24812288
17.
Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.
Am J Physiol Cell Physiol
; 307(1): C2-13, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24740541
18.
Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury.
J Pharmacol Exp Ther
; 349(3): 480-6, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24706986
19.
Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis.
Nat Commun
; 15(1): 210, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38172207
20.
Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa.
J Clin Invest
; 134(3)2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38051587